node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
PA0856 | PA3611 | PA0856 | PA3611 | Hypothetical protein; Product name confidence: Class 4 (Homologs of previously reported genes of unknown function, or no similarity to any previously reported sequences). | Hypothetical protein; Product name confidence: Class 4 (Homologs of previously reported genes of unknown function, or no similarity to any previously reported sequences). | 0.489 |
PA3611 | PA0856 | PA3611 | PA0856 | Hypothetical protein; Product name confidence: Class 4 (Homologs of previously reported genes of unknown function, or no similarity to any previously reported sequences). | Hypothetical protein; Product name confidence: Class 4 (Homologs of previously reported genes of unknown function, or no similarity to any previously reported sequences). | 0.489 |
PA3611 | PA3612 | PA3611 | PA3612 | Hypothetical protein; Product name confidence: Class 4 (Homologs of previously reported genes of unknown function, or no similarity to any previously reported sequences). | Conserved hypothetical protein; Product name confidence: Class 4 (Homologs of previously reported genes of unknown function, or no similarity to any previously reported sequences). | 0.982 |
PA3611 | algW | PA3611 | PA4446 | Hypothetical protein; Product name confidence: Class 4 (Homologs of previously reported genes of unknown function, or no similarity to any previously reported sequences). | AlgW protein; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa). | 0.489 |
PA3611 | dsbC | PA3611 | PA3737 | Hypothetical protein; Product name confidence: Class 4 (Homologs of previously reported genes of unknown function, or no similarity to any previously reported sequences). | Thiol:disulfide interchange protein DsbC; Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process; Belongs to the thioredoxin family. DsbC subfamily. | 0.429 |
PA3611 | exsB | PA3611 | PA1712 | Hypothetical protein; Product name confidence: Class 4 (Homologs of previously reported genes of unknown function, or no similarity to any previously reported sequences). | Exoenzyme S synthesis protein B; Involved in the synthesis of the type III secretion system (T3SS), also called injectisome, which is used to inject bacterial effector proteins into eukaryotic host cells. Pilot protein that is required for the proper localization of the secretin PscC in the outer membrane. Necessary for full in vivo virulence ; Belongs to the ExsB/YscW family. | 0.697 |
PA3611 | gmhA | PA3611 | PA4425 | Hypothetical protein; Product name confidence: Class 4 (Homologs of previously reported genes of unknown function, or no similarity to any previously reported sequences). | Sedoheptulose 7-phosphate isomerase GmhA; Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate; Belongs to the SIS family. GmhA subfamily. | 0.459 |
PA3611 | potD | PA3611 | PA3610 | Hypothetical protein; Product name confidence: Class 4 (Homologs of previously reported genes of unknown function, or no similarity to any previously reported sequences). | Polyamine transport protein PotD; Product name confidence: Class 2 (High similarity to functionally studied protein). | 0.889 |
PA3611 | xcpQ | PA3611 | PA3105 | Hypothetical protein; Product name confidence: Class 4 (Homologs of previously reported genes of unknown function, or no similarity to any previously reported sequences). | General secretion pathway protein D; Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins (Probable). This subunit forms the outer membrane channel (By similarity). Among its substrates are PrpL, elastase LasB, chitin binding protein D (CbpD), aminopeptidase PaAP, and metalloprotease ImpA. Belongs to the bacterial secretin family. GSP D subfamily. | 0.806 |
PA3612 | PA3611 | PA3612 | PA3611 | Conserved hypothetical protein; Product name confidence: Class 4 (Homologs of previously reported genes of unknown function, or no similarity to any previously reported sequences). | Hypothetical protein; Product name confidence: Class 4 (Homologs of previously reported genes of unknown function, or no similarity to any previously reported sequences). | 0.982 |
PA3612 | potD | PA3612 | PA3610 | Conserved hypothetical protein; Product name confidence: Class 4 (Homologs of previously reported genes of unknown function, or no similarity to any previously reported sequences). | Polyamine transport protein PotD; Product name confidence: Class 2 (High similarity to functionally studied protein). | 0.929 |
algW | PA3611 | PA4446 | PA3611 | AlgW protein; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa). | Hypothetical protein; Product name confidence: Class 4 (Homologs of previously reported genes of unknown function, or no similarity to any previously reported sequences). | 0.489 |
dsbC | PA3611 | PA3737 | PA3611 | Thiol:disulfide interchange protein DsbC; Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process; Belongs to the thioredoxin family. DsbC subfamily. | Hypothetical protein; Product name confidence: Class 4 (Homologs of previously reported genes of unknown function, or no similarity to any previously reported sequences). | 0.429 |
dsbC | gmhA | PA3737 | PA4425 | Thiol:disulfide interchange protein DsbC; Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process; Belongs to the thioredoxin family. DsbC subfamily. | Sedoheptulose 7-phosphate isomerase GmhA; Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate; Belongs to the SIS family. GmhA subfamily. | 0.471 |
exsB | PA3611 | PA1712 | PA3611 | Exoenzyme S synthesis protein B; Involved in the synthesis of the type III secretion system (T3SS), also called injectisome, which is used to inject bacterial effector proteins into eukaryotic host cells. Pilot protein that is required for the proper localization of the secretin PscC in the outer membrane. Necessary for full in vivo virulence ; Belongs to the ExsB/YscW family. | Hypothetical protein; Product name confidence: Class 4 (Homologs of previously reported genes of unknown function, or no similarity to any previously reported sequences). | 0.697 |
gmhA | PA3611 | PA4425 | PA3611 | Sedoheptulose 7-phosphate isomerase GmhA; Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate; Belongs to the SIS family. GmhA subfamily. | Hypothetical protein; Product name confidence: Class 4 (Homologs of previously reported genes of unknown function, or no similarity to any previously reported sequences). | 0.459 |
gmhA | dsbC | PA4425 | PA3737 | Sedoheptulose 7-phosphate isomerase GmhA; Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate; Belongs to the SIS family. GmhA subfamily. | Thiol:disulfide interchange protein DsbC; Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process; Belongs to the thioredoxin family. DsbC subfamily. | 0.471 |
potD | PA3611 | PA3610 | PA3611 | Polyamine transport protein PotD; Product name confidence: Class 2 (High similarity to functionally studied protein). | Hypothetical protein; Product name confidence: Class 4 (Homologs of previously reported genes of unknown function, or no similarity to any previously reported sequences). | 0.889 |
potD | PA3612 | PA3610 | PA3612 | Polyamine transport protein PotD; Product name confidence: Class 2 (High similarity to functionally studied protein). | Conserved hypothetical protein; Product name confidence: Class 4 (Homologs of previously reported genes of unknown function, or no similarity to any previously reported sequences). | 0.929 |
xcpQ | PA3611 | PA3105 | PA3611 | General secretion pathway protein D; Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins (Probable). This subunit forms the outer membrane channel (By similarity). Among its substrates are PrpL, elastase LasB, chitin binding protein D (CbpD), aminopeptidase PaAP, and metalloprotease ImpA. Belongs to the bacterial secretin family. GSP D subfamily. | Hypothetical protein; Product name confidence: Class 4 (Homologs of previously reported genes of unknown function, or no similarity to any previously reported sequences). | 0.806 |