node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
alr | dadX | PA4930 | PA5302 | Biosynthetic alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. Provides the D-alanine required for cell wall biosynthesis. Belongs to the alanine racemase family. | Catabolic alanine racemase; Isomerizes L-alanine to D-alanine which is then oxidized to pyruvate by DadA. | 0.914 |
alr | ddlA | PA4930 | PA4201 | Biosynthetic alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. Provides the D-alanine required for cell wall biosynthesis. Belongs to the alanine racemase family. | D-alanine-D-alanine ligase A; Cell wall formation. | 0.980 |
alr | ddlB | PA4930 | PA4410 | Biosynthetic alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. Provides the D-alanine required for cell wall biosynthesis. Belongs to the alanine racemase family. | D-alanine--D-alanine ligase; Cell wall formation. | 0.956 |
alr | ftsW | PA4930 | PA4413 | Biosynthetic alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. Provides the D-alanine required for cell wall biosynthesis. Belongs to the alanine racemase family. | Cell division protein FtsW; Peptidoglycan polymerase that is essential for cell division. Belongs to the SEDS family. FtsW subfamily. | 0.579 |
alr | murC | PA4930 | PA4411 | Biosynthetic alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. Provides the D-alanine required for cell wall biosynthesis. Belongs to the alanine racemase family. | UDP-N-acetylmuramate--alanine ligase; Cell wall formation; Belongs to the MurCDEF family. | 0.724 |
alr | murD | PA4930 | PA4414 | Biosynthetic alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. Provides the D-alanine required for cell wall biosynthesis. Belongs to the alanine racemase family. | UDP-N-acetylmuramoylalanine--D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA); Belongs to the MurCDEF family. | 0.683 |
alr | murF | PA4930 | PA4416 | Biosynthetic alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. Provides the D-alanine required for cell wall biosynthesis. Belongs to the alanine racemase family. | UDP-N-acetylmuramoylalanyl-D-glutamyl-2, 6-diaminopimelate--D-alanyl-D-alanyl ligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily. | 0.982 |
aroQ2 | ddlA | PA0245 | PA4201 | 3-dehydroquinate dehydratase; Catalyzes a trans-dehydration via an enolate intermediate. Belongs to the type-II 3-dehydroquinase family. | D-alanine-D-alanine ligase A; Cell wall formation. | 0.855 |
aroQ2 | ddlB | PA0245 | PA4410 | 3-dehydroquinate dehydratase; Catalyzes a trans-dehydration via an enolate intermediate. Belongs to the type-II 3-dehydroquinase family. | D-alanine--D-alanine ligase; Cell wall formation. | 0.829 |
dadX | alr | PA5302 | PA4930 | Catabolic alanine racemase; Isomerizes L-alanine to D-alanine which is then oxidized to pyruvate by DadA. | Biosynthetic alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. Provides the D-alanine required for cell wall biosynthesis. Belongs to the alanine racemase family. | 0.914 |
dadX | ddlA | PA5302 | PA4201 | Catabolic alanine racemase; Isomerizes L-alanine to D-alanine which is then oxidized to pyruvate by DadA. | D-alanine-D-alanine ligase A; Cell wall formation. | 0.966 |
dadX | ddlB | PA5302 | PA4410 | Catabolic alanine racemase; Isomerizes L-alanine to D-alanine which is then oxidized to pyruvate by DadA. | D-alanine--D-alanine ligase; Cell wall formation. | 0.958 |
dadX | ftsW | PA5302 | PA4413 | Catabolic alanine racemase; Isomerizes L-alanine to D-alanine which is then oxidized to pyruvate by DadA. | Cell division protein FtsW; Peptidoglycan polymerase that is essential for cell division. Belongs to the SEDS family. FtsW subfamily. | 0.487 |
dadX | murC | PA5302 | PA4411 | Catabolic alanine racemase; Isomerizes L-alanine to D-alanine which is then oxidized to pyruvate by DadA. | UDP-N-acetylmuramate--alanine ligase; Cell wall formation; Belongs to the MurCDEF family. | 0.572 |
dadX | murD | PA5302 | PA4414 | Catabolic alanine racemase; Isomerizes L-alanine to D-alanine which is then oxidized to pyruvate by DadA. | UDP-N-acetylmuramoylalanine--D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA); Belongs to the MurCDEF family. | 0.548 |
dadX | murF | PA5302 | PA4416 | Catabolic alanine racemase; Isomerizes L-alanine to D-alanine which is then oxidized to pyruvate by DadA. | UDP-N-acetylmuramoylalanyl-D-glutamyl-2, 6-diaminopimelate--D-alanyl-D-alanyl ligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily. | 0.956 |
ddlA | alr | PA4201 | PA4930 | D-alanine-D-alanine ligase A; Cell wall formation. | Biosynthetic alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. Provides the D-alanine required for cell wall biosynthesis. Belongs to the alanine racemase family. | 0.980 |
ddlA | aroQ2 | PA4201 | PA0245 | D-alanine-D-alanine ligase A; Cell wall formation. | 3-dehydroquinate dehydratase; Catalyzes a trans-dehydration via an enolate intermediate. Belongs to the type-II 3-dehydroquinase family. | 0.855 |
ddlA | dadX | PA4201 | PA5302 | D-alanine-D-alanine ligase A; Cell wall formation. | Catabolic alanine racemase; Isomerizes L-alanine to D-alanine which is then oxidized to pyruvate by DadA. | 0.966 |
ddlA | ddlB | PA4201 | PA4410 | D-alanine-D-alanine ligase A; Cell wall formation. | D-alanine--D-alanine ligase; Cell wall formation. | 0.913 |