node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
PA0490 | ppgL | PA0490 | PA4204 | Hypothetical protein; Product name confidence: Class 4 (Homologs of previously reported genes of unknown function, or no similarity to any previously reported sequences). | Periplasmic gluconolactonase, PpgL; Product name confidence: Class 1: Function experimentally demonstrated in P. aeruginosa. | 0.455 |
PA0853 | ppgL | PA0853 | PA4204 | Probable oxidoreductase; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene). | Periplasmic gluconolactonase, PpgL; Product name confidence: Class 1: Function experimentally demonstrated in P. aeruginosa. | 0.461 |
PA0989 | PA2858 | PA0989 | PA2858 | Hypothetical protein; Product name confidence: Class 4 (Homologs of previously reported genes of unknown function, or no similarity to any previously reported sequences). | Conserved hypothetical protein; Product name confidence: Class 4 (Homologs of previously reported genes of unknown function, or no similarity to any previously reported sequences). | 0.880 |
PA0989 | ppgL | PA0989 | PA4204 | Hypothetical protein; Product name confidence: Class 4 (Homologs of previously reported genes of unknown function, or no similarity to any previously reported sequences). | Periplasmic gluconolactonase, PpgL; Product name confidence: Class 1: Function experimentally demonstrated in P. aeruginosa. | 0.587 |
PA1225 | ddlA | PA1225 | PA4201 | Probable NAD(P)H dehydrogenase; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene). | D-alanine-D-alanine ligase A; Cell wall formation. | 0.700 |
PA1225 | nmoA | PA1225 | PA4202 | Probable NAD(P)H dehydrogenase; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene). | Hypothetical protein; Nitronate monooxygenase that uses molecular oxygen to catalyze the oxidative denitrification of alkyl nitronates. The toxin propionate 3-nitronate (P3N) is the best substrate (and the presumed physiological substrate), but this enzyme is also active on other primary and secondary nitronates such as propyl-1-nitronate, ethylnitronate, pentyl-1-nitronate, butyl-1-nitronate and propyl-2- nitronate. Is likely involved in the degradation of P3N, that allows P.aeruginosa PAO1 to grow on 3-nitropropionate/P3N as the sole nitrogen source. Also functions in the detoxificat [...] | 0.820 |
PA1225 | nmoR | PA1225 | PA4203 | Probable NAD(P)H dehydrogenase; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene). | Probable transcriptional regulator; Represses its own transcription and the expression of nmoA, a nitronate monooxygenase. The nmoA-nmoR intergenic region is the sole direct binding site of NmoR across the P.aeruginosa PAO1 genome. Other genes seem also to be under negative control of NmoR, especially PA1225 and the hemO gene; Belongs to the LysR transcriptional regulatory family. | 0.830 |
PA1225 | ppgL | PA1225 | PA4204 | Probable NAD(P)H dehydrogenase; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene). | Periplasmic gluconolactonase, PpgL; Product name confidence: Class 1: Function experimentally demonstrated in P. aeruginosa. | 0.802 |
PA2265 | gcd | PA2265 | PA2290 | Gluconate dehydrogenase; Product name confidence: Class 2 (High similarity to functionally studied protein). | Glucose dehydrogenase; Product name confidence: Class 2 (High similarity to functionally studied protein). | 0.911 |
PA2265 | ppgL | PA2265 | PA4204 | Gluconate dehydrogenase; Product name confidence: Class 2 (High similarity to functionally studied protein). | Periplasmic gluconolactonase, PpgL; Product name confidence: Class 1: Function experimentally demonstrated in P. aeruginosa. | 0.500 |
PA2858 | PA0989 | PA2858 | PA0989 | Conserved hypothetical protein; Product name confidence: Class 4 (Homologs of previously reported genes of unknown function, or no similarity to any previously reported sequences). | Hypothetical protein; Product name confidence: Class 4 (Homologs of previously reported genes of unknown function, or no similarity to any previously reported sequences). | 0.880 |
PA2858 | ppgL | PA2858 | PA4204 | Conserved hypothetical protein; Product name confidence: Class 4 (Homologs of previously reported genes of unknown function, or no similarity to any previously reported sequences). | Periplasmic gluconolactonase, PpgL; Product name confidence: Class 1: Function experimentally demonstrated in P. aeruginosa. | 0.588 |
ddlA | PA1225 | PA4201 | PA1225 | D-alanine-D-alanine ligase A; Cell wall formation. | Probable NAD(P)H dehydrogenase; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene). | 0.700 |
ddlA | nmoA | PA4201 | PA4202 | D-alanine-D-alanine ligase A; Cell wall formation. | Hypothetical protein; Nitronate monooxygenase that uses molecular oxygen to catalyze the oxidative denitrification of alkyl nitronates. The toxin propionate 3-nitronate (P3N) is the best substrate (and the presumed physiological substrate), but this enzyme is also active on other primary and secondary nitronates such as propyl-1-nitronate, ethylnitronate, pentyl-1-nitronate, butyl-1-nitronate and propyl-2- nitronate. Is likely involved in the degradation of P3N, that allows P.aeruginosa PAO1 to grow on 3-nitropropionate/P3N as the sole nitrogen source. Also functions in the detoxificat [...] | 0.855 |
ddlA | nmoR | PA4201 | PA4203 | D-alanine-D-alanine ligase A; Cell wall formation. | Probable transcriptional regulator; Represses its own transcription and the expression of nmoA, a nitronate monooxygenase. The nmoA-nmoR intergenic region is the sole direct binding site of NmoR across the P.aeruginosa PAO1 genome. Other genes seem also to be under negative control of NmoR, especially PA1225 and the hemO gene; Belongs to the LysR transcriptional regulatory family. | 0.690 |
ddlA | ppgL | PA4201 | PA4204 | D-alanine-D-alanine ligase A; Cell wall formation. | Periplasmic gluconolactonase, PpgL; Product name confidence: Class 1: Function experimentally demonstrated in P. aeruginosa. | 0.781 |
gcd | PA2265 | PA2290 | PA2265 | Glucose dehydrogenase; Product name confidence: Class 2 (High similarity to functionally studied protein). | Gluconate dehydrogenase; Product name confidence: Class 2 (High similarity to functionally studied protein). | 0.911 |
gcd | ppgL | PA2290 | PA4204 | Glucose dehydrogenase; Product name confidence: Class 2 (High similarity to functionally studied protein). | Periplasmic gluconolactonase, PpgL; Product name confidence: Class 1: Function experimentally demonstrated in P. aeruginosa. | 0.619 |
nmoA | PA1225 | PA4202 | PA1225 | Hypothetical protein; Nitronate monooxygenase that uses molecular oxygen to catalyze the oxidative denitrification of alkyl nitronates. The toxin propionate 3-nitronate (P3N) is the best substrate (and the presumed physiological substrate), but this enzyme is also active on other primary and secondary nitronates such as propyl-1-nitronate, ethylnitronate, pentyl-1-nitronate, butyl-1-nitronate and propyl-2- nitronate. Is likely involved in the degradation of P3N, that allows P.aeruginosa PAO1 to grow on 3-nitropropionate/P3N as the sole nitrogen source. Also functions in the detoxificat [...] | Probable NAD(P)H dehydrogenase; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene). | 0.820 |
nmoA | ddlA | PA4202 | PA4201 | Hypothetical protein; Nitronate monooxygenase that uses molecular oxygen to catalyze the oxidative denitrification of alkyl nitronates. The toxin propionate 3-nitronate (P3N) is the best substrate (and the presumed physiological substrate), but this enzyme is also active on other primary and secondary nitronates such as propyl-1-nitronate, ethylnitronate, pentyl-1-nitronate, butyl-1-nitronate and propyl-2- nitronate. Is likely involved in the degradation of P3N, that allows P.aeruginosa PAO1 to grow on 3-nitropropionate/P3N as the sole nitrogen source. Also functions in the detoxificat [...] | D-alanine-D-alanine ligase A; Cell wall formation. | 0.855 |