STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
azuAzurin precursor; Transfers electrons from cytochrome c551 to cytochrome oxidase. (148 aa)    
Predicted Functional Partners:
nirM
Cytochrome c-551 precursor; Electron donor for cytochrome cd1 in nitrite and nitrate respiration.
   
  
 0.956
nirS
Nitrite reductase precursor; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa).
   
 
 0.942
ccpR
Cytochrome c551 peroxidase precursor; Catalyzes the peroxidative oxidation of azurin and cytochrome c551. Likely to provide protection against toxic peroxides.
   
  
 0.901
oprC
Putative copper transport outer membrane porin OprC precursor; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa).
  
 
 0.865
PA4429
Probable cytochrome c1 precursor; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene).
  
  
 0.811
PA2807
Hypothetical protein; Product name confidence: Class 4 (Homologs of previously reported genes of unknown function, or no similarity to any previously reported sequences).
      
 0.787
oprG
Outer membrane protein OprG precursor; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa).
   
  
 0.745
oprI
Outer membrane lipoprotein OprI precursor; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa).
   
    0.715
algP
Alginate regulatory protein AlgP; The promoter for a critical alginate biosynthetic gene, AlgD, encoding GDP-mannose dehydrogenase, is activated only under conditions reminiscent of the cystic fibrosis lung (i.e. under high osmolarity), and at least two regulatory genes, AlgP and AlgQ, have been implicated in this activation process.
   
  
 0.714
oprF
Major porin and structural outer membrane porin OprF precursor; Has porin activity, forming small water-filled channels. Also has a structural role in determining cell shape and ability to grow in low-osmolarity medium; Belongs to the outer membrane OOP (TC 1.B.6) superfamily.
   
  
 0.700
Your Current Organism:
Pseudomonas aeruginosa
NCBI taxonomy Id: 208964
Other names: P. aeruginosa PAO1, Pseudomonas aeruginosa PAO1, Pseudomonas sp. PAO1
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