STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
adhAAlcohol dehydrogenase; Product name confidence: Class 2 (High similarity to functionally studied protein). (342 aa)    
Predicted Functional Partners:
adhC
Alcohol dehydrogenase class III; Product name confidence: Class 2 (High similarity to functionally studied protein); Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily.
  
 
0.953
exaA
Quinoprotein ethanol dehydrogenase; Catalyzes the oxidation of primary alcohols to the corresponding aldehydes, except for methanol, which is a very poor substrate. ExaA is also able to use secondary alcohols as well as amino alcohols like ethanolamine and l-amino-2-propanol, and aldehydes as substrates; Belongs to the bacterial PQQ dehydrogenase family.
   
 
 0.950
exaC
NAD+ dependent aldehyde dehydrogenase ExaC; Product name confidence: Class 1: Function experimentally demonstrated in P. aeruginosa; Belongs to the aldehyde dehydrogenase family.
 
 
 0.944
ccoN2
Cytochrome c oxidase, cbb3-type, CcoN subunit; Product name confidence: Class 1: Function experimentally demonstrated in P. aeruginosa; Belongs to the heme-copper respiratory oxidase family.
   
  
 0.922
PA2275
Probable alcohol dehydrogenase (Zn-dependent); Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene).
  
  
 
0.920
PA5475
Hypothetical protein; Catalyzes the transfer of an acetyl group from acetyl coenzyme A (AcCoA) to an acceptor substrate and releases both CoA and the acetylated product. It prefers the antibiotic chloramphenicol.
  
  
 0.917
PA1027
Probable aldehyde dehydrogenase; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene); Belongs to the aldehyde dehydrogenase family.
 
 
 0.909
PA4022
Probable aldehyde dehydrogenase; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene); Belongs to the aldehyde dehydrogenase family.
 
 
 0.909
PA4899
Probable aldehyde dehydrogenase; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene); Belongs to the aldehyde dehydrogenase family.
 
 
 0.909
alkB2
Alkane-1-monooxygenase 2; Catalyzes the hydroxylation of n-alkanes in the presence of a NADH-rubredoxin reductase and rubredoxin. It preferably hydroxylases C12-C20 hydrocarbons; Belongs to the fatty acid desaturase type 1 family. AlkB subfamily.
     
 0.905
Your Current Organism:
Pseudomonas aeruginosa
NCBI taxonomy Id: 208964
Other names: P. aeruginosa PAO1, Pseudomonas aeruginosa PAO1, Pseudomonas sp. PAO1
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