STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
FDHFormate dehydrogenase; Catalyzes the NAD(+)-dependent oxidation of formate to carbon dioxide. Formate oxidation is the final step in the methanol oxidation pathway in methylotrophic microorganisms. Has a role in the detoxification of exogenous formate in non-methylotrophic organisms. (370 aa)    
Predicted Functional Partners:
CTHT_0070110
S-formylglutathione hydrolase; Serine hydrolase involved in the detoxification of formaldehyde.
     
 0.959
CTHT_0010500
Formyltetrahydrofolate deformylase-like protein.
    
  0.902
CTHT_0048880
Formamidase-like protein.
   
 
  0.900
CTHT_0012510
Malate synthase; Belongs to the malate synthase family.
  
 
 0.855
CTHT_0032190
Malate dehydrogenase.
  
 0.844
CTHT_0070260
Malate dehydrogenase.
  
 0.844
CTHT_0012530
Fumarate hydratase-like protein.
  
 
 0.840
CTHT_0062150
Malic enzyme-like protein.
    
 0.827
CTHT_0073000
Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.
   
 
 0.808
CTHT_0044390
Phosphoenolpyruvate carboxykinase-like protein.
   
 
  0.805
Your Current Organism:
Chaetomium thermophilum
NCBI taxonomy Id: 759272
Other names: C. thermophilum var. thermophilum DSM 1495, Chaetomium thermophilum var. thermophilum DSM 1495
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