STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
defPutative polypeptide deformylase; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions. (204 aa)    
Predicted Functional Partners:
rl22
50S ribosomal protein L22; This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity).
   
   0.932
ropA
Peptidyl-prolyl isomerase RopA (trigger factor); Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase; Belongs to the FKBP-type PPIase family. Tig subfamily.
  
 
 0.865
rs20
Putative 30S ribosomal protein S20; Binds directly to 16S ribosomal RNA.
  
 
 0.852
rplU
50S ribosomal protein L21; This protein binds to 23S rRNA in the presence of protein L20; Belongs to the bacterial ribosomal protein bL21 family.
 
 
 0.852
rl17
Best Blastp Hit: sp|P20277|RL17_BACSU 50S RIBOSOMAL PROTEIN L17 (BL15) (BL21) >gi|80370|pir||F32307 ribosomal protein L17 - Bacillus subtilis >gi|142464|gb|AAA22218.1| (M26414) ribosomal protein L17 [Bacillus subtilis] >gi|1044992|gb|AAB06827.1| (L47971) ribosomal protein L17 [Bacillus subtilis] >gi|2632411|emb|CAB11920.1| (Z99104) ribosomal protein L17 (BL15) [Bacillus subtilis].
   
   0.845
rpsU
Best Blastp Hit: pir||T43742 ribosomal protein S21 [imported] - Listeria monocytogenes >gi|5689043|dbj|BAA82793.1| (AB023064) 30S ribosomal protein S21 [Listeria monocytogenes]; Belongs to the bacterial ribosomal protein bS21 family.
  
 
 0.844
rpsO
30S ribosomal protein S15; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
 
   0.843
rpsP
30S ribosomal protein S16; Best Blastp Hit: dbj|BAB06202.1| (AP001515) ribosomal protein S16 (BS17) [Bacillus halodurans]; Belongs to the bacterial ribosomal protein bS16 family.
 
   0.831
rplD
50S ribosomal protein L4; Forms part of the polypeptide exit tunnel.
  
 
   0.829
rpsD
30S ribosomal protein S4; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
  
   0.829
Your Current Organism:
Streptococcus mutans
NCBI taxonomy Id: 210007
Other names: S. mutans UA159, Streptococcus mutans UA159, Streptococcus mutans str. UA159
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