STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SMU_1486cBest Blastp Hit: pir||E72330 conserved hypothetical protein - Thermotoga maritima (strain MSB8) >gi|4981334|gb|AAD35886.1|AE001748_2 (AE001748) conserved hypothetical protein [Thermotoga maritima]; Belongs to the PHP hydrolase family. HisK subfamily. (244 aa)    
Predicted Functional Partners:
hisD
Putative histidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine.
  
 
 0.938
hisC
Best Blastp Hit: sp|Q02135|HIS8_LACLA HISTIDINOL-PHOSPHATE AMINOTRANSFERASE (IMIDAZOLE ACETOL-PHOSPHATE TRANSAMINASE) >gi|2565139|gb|AAB81901.1| (U92974) HisC [Lactococcus lactis]; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
  
 
 0.924
SMU_1485c
Putative endonuclease; Best Blastp Hit: emb|CAB72623.1| (AL139074) putative endonuclease [Campylobacter jejuni].
       0.777
SMU_1484c
Conserved hypothetical protein; Best Blastp Hit: emb|CAB72624.1| (AL139074) hypothetical protein Cj0140 [Campylobacter jejuni].
       0.775
hisB
Best Blastp Hit: dbj|BAB07300.1| (AP001519) imidazoleglycerol-phosphate dehydratase [Bacillus halodurans].
  
  
 0.635
hisI
Putative phosphoribosyl-ATP pyrophosphatase / phosphoribosyl-AMP cyclohydrolase; Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP.
  
  
 0.634
SMU_1482c
Conserved hypothetical protein; Best Blastp Hit: gb|AAD28224.1|AF121254_6 (AF121254) unknown [Enterococcus faecium].
  
    0.594
SMU_1483c
Conserved hypothetical protein; Best Blastp Hit: dbj|BAB04222.1| (AP001508) unknown conserved protein in others [Bacillus halodurans].
       0.573
SMU_1487
Best Blastp Hit: pir||D72115 conserved hypothetical protein CP0630 [imported] - Chlamydophila pneumoniae (strains CWL029 and AR39) >gi|4376408|gb|AAD18296.1| (AE001600) Hypothetical Protein [Chlamydophila pneumoniae] >gi|7189544|gb|AAF38445.1| (AE002221) conserved hypothetical protein [Chlamydophila pneumoniae AR39] >gi|8978516|dbj|BAA98353.1| (AP002545) hypothetical protein [Chlamydophila pneumoniae].
       0.537
SMU_561c
Putative hydrolase (MutT family); Best Blastp Hit: dbj|BAA33629.1| (AB012957) unknown [Vibrio cholerae].
 
     0.497
Your Current Organism:
Streptococcus mutans
NCBI taxonomy Id: 210007
Other names: S. mutans UA159, Streptococcus mutans UA159, Streptococcus mutans str. UA159
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.