STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
rncPutative ribonuclease III; Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity). Belongs to the ribonuclease III family. (231 aa)    
Predicted Functional Partners:
rl19
50S ribosomal protein L19; This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.
 
 
 0.974
rplM
50S ribosomal protein L13; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.
   
 
 0.945
rpsI
Best Blastp Hit: sp|P07842|RS9_BACST 30S RIBOSOMAL PROTEIN S9 (BS10) >gi|70924|pir||R3BS9 ribosomal protein S9 - Bacillus stearothermophilus; Belongs to the universal ribosomal protein uS9 family.
   
 
 0.933
rl22
50S ribosomal protein L22; This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity).
   
 
 0.924
rl33
Best Blastp Hit: sp|P23375|RL33_BACST 50S RIBOSOMAL PROTEIN L33 >gi|477793|pir||B48396 ribosomal protein L33 - Bacillus stearothermophilus >gi|240272|gb|AAB20569.1| BstL33=50S ribosomal subunit protein [Bacillus stearothermophilus, Peptide, 49 aa] >gi|243175|gb|AAB21086.1| ribosomal protein L33 [Bacillus stearothermophilus, Peptide, 49 aa] >gi|228174|prf||1718186B ribosomal protein L33 [Bacillus stearothermophilus]; Belongs to the bacterial ribosomal protein bL33 family.
   
 
 0.917
rpsP
30S ribosomal protein S16; Best Blastp Hit: dbj|BAB06202.1| (AP001515) ribosomal protein S16 (BS17) [Bacillus halodurans]; Belongs to the bacterial ribosomal protein bS16 family.
 
 
 0.909
rpsO
30S ribosomal protein S15; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
   
 
 0.905
rpmA
Best Blastp Hit: sp|P05657|RL27_BACSU 50S RIBOSOMAL PROTEIN L27 (BL30) (BL24) >gi|80371|pir||C21895 ribosomal protein L27 - Bacillus subtilis >gi|40186|emb|CAA26492.1| (X02656) homologous to E.coli ribosomal protein L27 [Bacillus subtilis] >gi|2635259|emb|CAB14754.1| (Z99118) ribosomal protein L27 (BL24) [Bacillus subtilis]; Belongs to the bacterial ribosomal protein bL27 family.
  
 
 0.905
rs6
30S ribosomal protein S6; Binds together with S18 to 16S ribosomal RNA.
   
 
 0.892
rpmF
50S ribosomal protein L32; Best Blastp Hit: gi|15903984|ref|NP_359534.1| (NC_003098) 50S Ribosomal protein L32 [Streptococcus pneumoniae R6]; Belongs to the bacterial ribosomal protein bL32 family.
  
   0.892
Your Current Organism:
Streptococcus mutans
NCBI taxonomy Id: 210007
Other names: S. mutans UA159, Streptococcus mutans UA159, Streptococcus mutans str. UA159
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