STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
covSPutative histidine kinase CovS; Best Blastp Hit: emb|CAB65452.1| (AJ012051) VicK protein [Streptococcus pyogenes]. (450 aa)    
Predicted Functional Partners:
covR
Putative response regulator CovR; Best Blastp Hit: emb|CAB65451.1| (AJ012051) VicR protein [Streptococcus pyogenes].
 0.999
covX
Conserved hypothetical protein CovX (VicX); Best Blastp Hit: emb|CAB65440.1| (AJ012049) VicX protein [Streptococcus pneumoniae].
  
  
 0.934
gcrR
Response regulator GcrR for glucan-binding protein C; Best Blastp Hit: dbj|BAA85986.1| (AB024522) gcrR [Streptococcus mutans].
 
 0.927
SMU_1146c
Putative response regulator; Similar to RumR and ScnR; Best Blastp Hit: pir||T09003 response regulator homolog scnR - Streptococcus pyogenes >gi|2502067|gb|AAB92599.1| (AF026542) ScnR [Streptococcus pyogenes].
 
 0.868
SMU_1038c
Putative response regulator; Best Blastp Hit: dbj|BAB04539.1| (AP001509) two-component response regulator [Bacillus halodurans].
 
 0.825
ciaR
Best Blastp Hit: emb|CAB54564.1| (AJ005926) response regulator [Streptococcus pneumoniae].
 
 0.819
scnR
Best Blastp Hit: pir||T09003 response regulator homolog scnR - Streptococcus pyogenes >gi|2502067|gb|AAB92599.1| (AF026542) ScnR [Streptococcus pyogenes].
 
 0.819
SMU_659
Best Blastp Hit: emb|CAA11808.1| (AJ224003) response regulator [Carnobacterium divergens].
 
 0.801
SMU_927
Putative response regulator; Best Blastp Hit: pir||D70624 probable two-component regulatory protein - Mycobacterium tuberculosis (strain H37RV) >gi|1869995|emb|CAB06846.1| (Z92539) hypothetical protein Rv1033c [Mycobacterium tuberculosis] >gi|2979514|gb|AAC06144.1| (U88959) response regulator homolog TrcR [Mycobacterium tuberculosis].
 
 0.767
SMU_1008
Putative response regulator; Best Blastp Hit: gb|AAD10258.1| (AF036964) putative response regulator [Lactobacillus sakei].
 
 0.744
Your Current Organism:
Streptococcus mutans
NCBI taxonomy Id: 210007
Other names: S. mutans UA159, Streptococcus mutans UA159, Streptococcus mutans str. UA159
Server load: low (18%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.