STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
amyAIntracellular alpha-amylase; Best Blastp Hit: gb|AAC35010.1| (AF055987) intracellular a-amylase [Streptococcus mutans]. (486 aa)    
Predicted Functional Partners:
pulA
Putative pullulanase; Best Blastp Hit: prf||1808262A thermostable pullulanase [Bacillus stearothermophilus]; Belongs to the glycosyl hydrolase 13 family.
 
 
 0.972
glgB
Putative 1,4-alpha-glucan branching enzyme; Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position; Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.
  
 
 0.970
glgP
Putative glycogen phosphorylase; Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.
  
 0.966
ccpA
Catabolite control protein A, CcpA; Global transcriptional regulator of carbon catabolite repression (CCR) and carbon catabolite activation (CCA), which ensures optimal energy usage under diverse conditions.
  
  
 0.930
malQ
Best Blastp Hit: sp|P29851|MALQ_STRPN 4-ALPHA-GLUCANOTRANSFERASE (AMYLOMALTASE) (DISPROPORTIONATING ENZYME) (D-ENZYME) >gi|153704|gb|AAA26923.1| (J01796) amylomaltase [Streptococcus pneumoniae].
  
 
 0.925
phsG
Glycogen phosphorylase; Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.
  
 0.919
SMU_2046c
Conserved hypothetical protein.
  
 
 0.906
ptsG
Putative PTS system, glucose-specific IIABC component; Best Blastp Hit: gb|AAD00281.1| (U78600) putative ptsG## protein [Streptococcus mutans].
  
  
 0.653
SMU_16
Putative amino acid permease; Best Blastp Hit: pir||D69814 metabolite transporter homolog yfnA - Bacillus subtilis >gi|2633047|emb|CAB12553.1| (Z99107) similar to metabolite transporter [Bacillus subtilis] >gi|2633058|emb|CAB12563.1| (Z99108) similar to metabolite transporter [Bacillus subtilis].
   
 0.614
SMU_2104
Best Blastp Hit: pir||F69769 conserved hypothetical protein ydaO - Bacillus subtilis >gi|1881242|dbj|BAA19269.1| (AB001488) FUNCTION UNKNOWN, WEAK SIMILARITY TO YEEF_ECOLI. [Bacillus subtilis] >gi|2632732|emb|CAB12239.1| (Z99106) similar to hypothetical proteins [Bacillus subtilis].
   
 0.614
Your Current Organism:
Streptococcus mutans
NCBI taxonomy Id: 210007
Other names: S. mutans UA159, Streptococcus mutans UA159, Streptococcus mutans str. UA159
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.