node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
SMU_1771c | syv | SMU_1771c | SMU_1770 | Hypothetical protein; Best Blastp Hit: pir||D69451 conserved hypothetical protein AF1613 - Archaeoglobus fulgidus >gi|2648944|gb|AAB89634.1| (AE000991) conserved hypothetical protein [Archaeoglobus fulgidus]. | Putative valyl-tRNA synthetase; Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA- dependent manner; Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily. | 0.762 |
alaS | argS | SMU_650 | SMU_2098 | Putative alanyl-tRNA synthetase (alanine--tRNA ligase); Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain. | Putative arginyl-tRNA synthase; Best Blastp Hit: gb|AAF86984.1|AF282249_3 (AF282249) ArgS [Lactococcus lactis subsp. lactis]. | 0.402 |
alaS | guaA | SMU_650 | SMU_1066 | Putative alanyl-tRNA synthetase (alanine--tRNA ligase); Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain. | Putative GMP synthase; Catalyzes the synthesis of GMP from XMP. | 0.580 |
alaS | ileS | SMU_650 | SMU_558 | Putative alanyl-tRNA synthetase (alanine--tRNA ligase); Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain. | isoleucine-tRNA synthetase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily. | 0.769 |
alaS | proS | SMU_650 | SMU_1783 | Putative alanyl-tRNA synthetase (alanine--tRNA ligase); Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain. | Putative prolyl-tRNA synthetase; Catalyzes the attachment of proline to tRNA(Pro) in a two- step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and inv [...] | 0.477 |
alaS | sygA | SMU_650 | SMU_445 | Putative alanyl-tRNA synthetase (alanine--tRNA ligase); Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain. | Best Blastp Hit: dbj|BAB05089.1| (AP001511) glycyl-tRNA synthetase (alpha subunit) [Bacillus halodurans]. | 0.566 |
alaS | syl | SMU_650 | SMU_1943 | Putative alanyl-tRNA synthetase (alanine--tRNA ligase); Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain. | Putative leucyl-tRNA synthetase; Best Blastp Hit: dbj|BAB07000.1| (AP001518) leucyl-tRNA synthetase [Bacillus halodurans]; Belongs to the class-I aminoacyl-tRNA synthetase family. | 0.733 |
alaS | sys | SMU_650 | SMU_1886 | Putative alanyl-tRNA synthetase (alanine--tRNA ligase); Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain. | Putative seryl-tRNA synthetase; Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L- seryl-tRNA(Sec), which will be further converted into selenocysteinyl- tRNA(Sec). | 0.555 |
alaS | syv | SMU_650 | SMU_1770 | Putative alanyl-tRNA synthetase (alanine--tRNA ligase); Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain. | Putative valyl-tRNA synthetase; Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA- dependent manner; Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily. | 0.821 |
argS | alaS | SMU_2098 | SMU_650 | Putative arginyl-tRNA synthase; Best Blastp Hit: gb|AAF86984.1|AF282249_3 (AF282249) ArgS [Lactococcus lactis subsp. lactis]. | Putative alanyl-tRNA synthetase (alanine--tRNA ligase); Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain. | 0.402 |
argS | guaA | SMU_2098 | SMU_1066 | Putative arginyl-tRNA synthase; Best Blastp Hit: gb|AAF86984.1|AF282249_3 (AF282249) ArgS [Lactococcus lactis subsp. lactis]. | Putative GMP synthase; Catalyzes the synthesis of GMP from XMP. | 0.943 |
argS | ileS | SMU_2098 | SMU_558 | Putative arginyl-tRNA synthase; Best Blastp Hit: gb|AAF86984.1|AF282249_3 (AF282249) ArgS [Lactococcus lactis subsp. lactis]. | isoleucine-tRNA synthetase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily. | 0.911 |
argS | proS | SMU_2098 | SMU_1783 | Putative arginyl-tRNA synthase; Best Blastp Hit: gb|AAF86984.1|AF282249_3 (AF282249) ArgS [Lactococcus lactis subsp. lactis]. | Putative prolyl-tRNA synthetase; Catalyzes the attachment of proline to tRNA(Pro) in a two- step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and inv [...] | 0.952 |
argS | sygA | SMU_2098 | SMU_445 | Putative arginyl-tRNA synthase; Best Blastp Hit: gb|AAF86984.1|AF282249_3 (AF282249) ArgS [Lactococcus lactis subsp. lactis]. | Best Blastp Hit: dbj|BAB05089.1| (AP001511) glycyl-tRNA synthetase (alpha subunit) [Bacillus halodurans]. | 0.487 |
argS | syl | SMU_2098 | SMU_1943 | Putative arginyl-tRNA synthase; Best Blastp Hit: gb|AAF86984.1|AF282249_3 (AF282249) ArgS [Lactococcus lactis subsp. lactis]. | Putative leucyl-tRNA synthetase; Best Blastp Hit: dbj|BAB07000.1| (AP001518) leucyl-tRNA synthetase [Bacillus halodurans]; Belongs to the class-I aminoacyl-tRNA synthetase family. | 0.918 |
argS | sys | SMU_2098 | SMU_1886 | Putative arginyl-tRNA synthase; Best Blastp Hit: gb|AAF86984.1|AF282249_3 (AF282249) ArgS [Lactococcus lactis subsp. lactis]. | Putative seryl-tRNA synthetase; Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L- seryl-tRNA(Sec), which will be further converted into selenocysteinyl- tRNA(Sec). | 0.893 |
argS | syv | SMU_2098 | SMU_1770 | Putative arginyl-tRNA synthase; Best Blastp Hit: gb|AAF86984.1|AF282249_3 (AF282249) ArgS [Lactococcus lactis subsp. lactis]. | Putative valyl-tRNA synthetase; Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA- dependent manner; Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily. | 0.856 |
guaA | alaS | SMU_1066 | SMU_650 | Putative GMP synthase; Catalyzes the synthesis of GMP from XMP. | Putative alanyl-tRNA synthetase (alanine--tRNA ligase); Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain. | 0.580 |
guaA | argS | SMU_1066 | SMU_2098 | Putative GMP synthase; Catalyzes the synthesis of GMP from XMP. | Putative arginyl-tRNA synthase; Best Blastp Hit: gb|AAF86984.1|AF282249_3 (AF282249) ArgS [Lactococcus lactis subsp. lactis]. | 0.943 |
guaA | ileS | SMU_1066 | SMU_558 | Putative GMP synthase; Catalyzes the synthesis of GMP from XMP. | isoleucine-tRNA synthetase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily. | 0.585 |