STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
manABest Blastp Hit: sp|Q59935|MANA_STRMU MANNOSE-6-PHOSPHATE ISOMERASE (PHOSPHOMANNOSE ISOMERASE) (PMI) (PHOSPHOHEXOMUTASE) >gi|451216|dbj|BAA04021.1| (D16594) Mannosephosphate Isomerase [Streptococcus mutans]. (316 aa)    
Predicted Functional Partners:
scrK
Putative fructokinase; Best Blastp Hit: sp|Q07211|SCRK_STRMU FRUCTOKINASE >gi|287459|dbj|BAA02467.1| (D13175) fructokinase [Streptococcus mutans].
 
 
 0.978
pgi
Glucose-6-phosphate isomerase; Best Blastp Hit: gb|AAD33517.1|AF132127_2 (AF132127) glucose-6-phosphate isomerase [Streptococcus mutans].
 
 
 0.970
ptnA
Putative PTS system, mannose-specific component IIAB; Best Blastp Hit: gb|AAD46485.1|AF130465_1 (AF130465) mannose-specific phosphotransferase system component IIAB [Streptococcus salivarius].
 
 
 0.957
nagB
Putative N-acetylglucosamine-6-phosphate isomerase; Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion.
     
 0.953
pfk
6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
  
 
 0.951
ptnC
Putative PTS system, mannose-specific component IIC; Best Blastp Hit: gb|AAD46486.1|AF130465_2 (AF130465) mannose-specific phosphotransferase system component IIC [Streptococcus salivarius].
 
 
  0.937
SMU_103
Putative PTS system, IIA component; Best Blastp Hit: gb|AAD46485.1|AF130465_1 (AF130465) mannose-specific phosphotransferase system component IIAB [Streptococcus salivarius].
    
 0.935
mtlD
Best Blastp Hit: sp|Q02418|MTLD_STRMU MANNITOL-1-PHOSPHATE 5-DEHYDROGENASE >gi|282315|pir||C44798 mannitol-1-phosphate 5-dehydrogenase (EC 1.1.1.17) mtlD - Streptococcus mutans >gi|153746|gb|AAA26942.1| (AF210133) mannitol-phosphate dehydrogenase [Streptococcus mutans].
  
 
 0.935
SMU_308
Best Blastp Hit: pir||T51721 sorbitol-6-phosphate 2-dehydrogenase (EC 1.1.1.140) [imported] - Streptococcus mutans >gi|4928282|gb|AAD33518.1|AF132127_3 (AF132127) sorbitol-6-phosphate dehydrogenase [Streptococcus mutans]; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
   
 
 0.933
SMU_1879
Putative PTS system, mannose-specific component IID; Best Blastp Hit: gb|AAD46487.1|AF130465_3 (AF130465) mannose-specific phosphotransferase system component IID [Streptococcus salivarius].
 
  
  0.931
Your Current Organism:
Streptococcus mutans
NCBI taxonomy Id: 210007
Other names: S. mutans UA159, Streptococcus mutans UA159, Streptococcus mutans str. UA159
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.