STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
gshABPutative glutamate-cysteine ligase; Synthesizes glutathione from L-glutamate and L-cysteine via gamma-L-glutamyl-L-cysteine. (754 aa)    
Predicted Functional Partners:
pepN
Aminopeptidase N, PepN; Best Blastp Hit: emb|CAB50785.1| (AJ007700) aminopeptidase N [Streptococcus thermophilus].
     
 0.908
ilvE
Best Blastp Hit: gb|AAF34406.1|AF164204_1 (AF164204) branched-chain amino acid aminotransferase [Lactococcus lactis subsp. cremoris] >gi|7620382|gb|AAF64593.1|AF169649_1 (AF169649) branched-chain aminotransferase IlvE [Lactococcus lactis].
     
 0.907
gltB
NADPH-dependent glutamate synthase (small subunit); Best Blastp Hit: dbj|BAA12742.1| (D85230) small subunit of NADH-dependent glutamate synthase [Plectonema boryanum].
     
 0.870
glnA
Best Blastp Hit: gb|AAC44800.1| (U61271) glutamine synthetase type 1 [Streptococcus agalactiae].
  
 
 0.866
cysK
Putative cysteine synthetase A; Best Blastp Hit: dbj|BAA88310.1| (AB028865) O-acetylserine lyase [Streptococcus suis]; Belongs to the cysteine synthase/cystathionine beta- synthase family.
    
 0.858
gshR
Glutathione reductase; Best Blastp Hit: dbj|BAA76640.1| (AB019579) glutathione reductase (GR) [Streptococcus mutans].
  
   
 0.840
SMU_913
Best Blastp Hit: dbj|BAB05820.1| (AP001514) NADP-specific glutamate dehydrogenase [Bacillus halodurans]; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
    
 0.813
metC
Best Blastp Hit: sp|Q08432|PATB_BACSU PUTATIVE AMINOTRANSFERASE B >gi|421526|pir||S32934 aminotransferase patB - Bacillus subtilis >gi|1934779|emb|CAB07910.1| (Z93933) aminotransferase [Bacillus subtilis] >gi|1934787|emb|CAB07924.1| (Z93934) aminotransferase [Bacillus subtilis] >gi|2231218|gb|AAB61979.1| (U63302) PatB [Bacillus subtilis] >gi|2635640|emb|CAB15133.1| (Z99120) aminotransferase [Bacillus subtilis].
   
 
  0.811
SMU_140
Putative glutathione reductase; Best Blastp Hit: emb|CAA73495.1| (Y13052) ORF454 [Staphylococcus sciuri].
  
   
 0.808
gltA
Best Blastp Hit: dbj|BAB05447.1| (AP001513) glutamate synthase (large subunit) [Bacillus halodurans].
     
 0.805
Your Current Organism:
Streptococcus mutans
NCBI taxonomy Id: 210007
Other names: S. mutans UA159, Streptococcus mutans UA159, Streptococcus mutans str. UA159
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