STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
gltBNADPH-dependent glutamate synthase (small subunit); Best Blastp Hit: dbj|BAA12742.1| (D85230) small subunit of NADH-dependent glutamate synthase [Plectonema boryanum]. (478 aa)    
Predicted Functional Partners:
gltA
Best Blastp Hit: dbj|BAB05447.1| (AP001513) glutamate synthase (large subunit) [Bacillus halodurans].
 0.999
glnA
Best Blastp Hit: gb|AAC44800.1| (U61271) glutamine synthetase type 1 [Streptococcus agalactiae].
  
 
 0.965
SMU_913
Best Blastp Hit: dbj|BAB05820.1| (AP001514) NADP-specific glutamate dehydrogenase [Bacillus halodurans]; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
  
 0.960
cnhA
Putative carbon-nitrogen hydrolase; Best Blastp Hit: pir||E69863 conserved hypothetical protein ykrU - Bacillus subtilis >gi|2633728|emb|CAB13230.1| (Z99111) similar to hypothetical proteins [Bacillus subtilis].
  
 0.926
pyrAB
Carbamoylphosphate synthetase, large subunit; Best Blastp Hit: emb|CAA03928.1| (AJ000109) carbamoylphosphate synthetase [Lactococcus lactis].
  
 
 0.921
glmS
Glucosamine-fructose-6-phosphate aminotransferase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
    
 0.916
purF
Phosphoribosylpyrophosphate amidotransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.
  
 
 0.916
pyrK
Putative dihydroorotate dehydrogenase, electron transfer subunit; Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD(+).
 
 
 0.908
pyrA
Best Blastp Hit: emb|CAB89872.1| (AJ132624) carbamoyl phosphate synthetase small subunit [Lactococcus lactis]; Belongs to the CarA family.
  
 
 0.908
gshAB
Putative glutamate-cysteine ligase; Synthesizes glutathione from L-glutamate and L-cysteine via gamma-L-glutamyl-L-cysteine.
     
 0.870
Your Current Organism:
Streptococcus mutans
NCBI taxonomy Id: 210007
Other names: S. mutans UA159, Streptococcus mutans UA159, Streptococcus mutans str. UA159
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