Export your current network:
... as a vector graphic:
SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc
... as short tabular text output:
TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)
... as tabular text output:
TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)
... as an XML summary:
structured XML interaction data, according to the 'PSI-MI' data standard
... protein node degrees:
node degree of proteins in your network (given the current score cut-off)
... network coordinates:
a flat-file format describing the coordinates and colors of nodes in the network
... protein sequences:
MFA: multi-fasta format - containing the aminoacid sequences in the network
... protein annotations:
a tab-delimited file describing the names, domains and descriptions of proteins in your network
... functional annotations:
a tab-delimited file containing all known functional terms of protiens in your network
Browse interactions in tabular form:
| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| glyA | purA | SMU_1082 | SMU_268 | Putative serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. | 0.835 |
| glyA | purB | SMU_1082 | SMU_59 | Putative serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Adenylosuccinate lyase; Best Blastp Hit: dbj|BAB04344.1| (AP001509) adenylosuccinate lyase [Bacillus halodurans]. | 0.805 |
| glyA | purC | SMU_1082 | SMU_29 | Putative serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Best Blastp Hit: sp|Q07296|PUR7_STRPN PHOSPHORIBOSYLAMINOIMIDAZOLE-SUCCINOCARBOXAMIDE SYNTHASE (SAICAR SYNTHETASE) >gi|625868|pir||A36941 phosphoribosylaminoimidazolesuccinocarboxamide synthase (EC 6.3.2.6) - Streptococcus pneumoniae >gi|295192|gb|AAA03540.1| (L15190) SAICAR synthetase [Streptococcus pneumoniae] >gi|663281|gb|AAA69512.1| (M36180) SAICAR synthetase [Streptococcus pneumoniae]. | 0.683 |
| glyA | purD | SMU_1082 | SMU_48 | Putative serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Putative phosphoribosylamine-glycine ligase; Best Blastp Hit: sp|Q9ZF44|PUR2_LACLA PHOSPHORIBOSYLAMINE--GLYCINE LIGASE (GARS) (GLYCINAMIDE RIBONUCLEOTIDE SYNTHETASE) (PHOSPHORIBOSYLGLYCINAMIDE SYNTHETASE) >gi|3892883|emb|CAA04374.1| (AJ000883) purD [Lactococcus lactis]. | 0.739 |
| glyA | purF | SMU_1082 | SMU_32 | Putative serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Phosphoribosylpyrophosphate amidotransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family. | 0.785 |
| glyA | purH | SMU_1082 | SMU_37 | Putative serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Best Blastp Hit: dbj|BAB04352.1| (AP001509) phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase [Bacillus halodurans]. | 0.992 |
| glyA | purL | SMU_1082 | SMU_30 | Putative serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Putative phosphoribosylformylglycinamidine synthase, (FGAM synthase); Best Blastp Hit: pir||C69492 phosphoribosylformylglycinamidine synthase (EC 6.3.5.3) component II - Archaeoglobus fulgidus >gi|2648599|gb|AAB89311.1| (AE000969) phosphoribosylformylglycinamidine synthase II (purL) [Archaeoglobus fulgidus]. | 0.946 |
| glyA | purM | SMU_1082 | SMU_34 | Putative serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Best Blastp Hit: gb|AAC16901.1| (AF016634) phosphoribosylformylglycinamide cyclo-ligase [Lactococcus lactis subsp. cremoris]. | 0.511 |
| glyA | purN | SMU_1082 | SMU_35 | Putative serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Putative phosphoribosylglycinamide formyltransferase (GART); Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate. | 0.961 |
| purA | glyA | SMU_268 | SMU_1082 | Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. | Putative serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.835 |
| purA | purB | SMU_268 | SMU_59 | Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. | Adenylosuccinate lyase; Best Blastp Hit: dbj|BAB04344.1| (AP001509) adenylosuccinate lyase [Bacillus halodurans]. | 0.998 |
| purA | purC | SMU_268 | SMU_29 | Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. | Best Blastp Hit: sp|Q07296|PUR7_STRPN PHOSPHORIBOSYLAMINOIMIDAZOLE-SUCCINOCARBOXAMIDE SYNTHASE (SAICAR SYNTHETASE) >gi|625868|pir||A36941 phosphoribosylaminoimidazolesuccinocarboxamide synthase (EC 6.3.2.6) - Streptococcus pneumoniae >gi|295192|gb|AAA03540.1| (L15190) SAICAR synthetase [Streptococcus pneumoniae] >gi|663281|gb|AAA69512.1| (M36180) SAICAR synthetase [Streptococcus pneumoniae]. | 0.872 |
| purA | purD | SMU_268 | SMU_48 | Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. | Putative phosphoribosylamine-glycine ligase; Best Blastp Hit: sp|Q9ZF44|PUR2_LACLA PHOSPHORIBOSYLAMINE--GLYCINE LIGASE (GARS) (GLYCINAMIDE RIBONUCLEOTIDE SYNTHETASE) (PHOSPHORIBOSYLGLYCINAMIDE SYNTHETASE) >gi|3892883|emb|CAA04374.1| (AJ000883) purD [Lactococcus lactis]. | 0.877 |
| purA | purE | SMU_268 | SMU_50 | Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. | Putative phosphoribosylaminoimidazole carboxylase, catalytic subunit; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). | 0.863 |
| purA | purF | SMU_268 | SMU_32 | Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. | Phosphoribosylpyrophosphate amidotransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family. | 0.663 |
| purA | purH | SMU_268 | SMU_37 | Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. | Best Blastp Hit: dbj|BAB04352.1| (AP001509) phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase [Bacillus halodurans]. | 0.991 |
| purA | purL | SMU_268 | SMU_30 | Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. | Putative phosphoribosylformylglycinamidine synthase, (FGAM synthase); Best Blastp Hit: pir||C69492 phosphoribosylformylglycinamidine synthase (EC 6.3.5.3) component II - Archaeoglobus fulgidus >gi|2648599|gb|AAB89311.1| (AE000969) phosphoribosylformylglycinamidine synthase II (purL) [Archaeoglobus fulgidus]. | 0.977 |
| purA | purM | SMU_268 | SMU_34 | Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. | Best Blastp Hit: gb|AAC16901.1| (AF016634) phosphoribosylformylglycinamide cyclo-ligase [Lactococcus lactis subsp. cremoris]. | 0.789 |
| purA | purN | SMU_268 | SMU_35 | Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. | Putative phosphoribosylglycinamide formyltransferase (GART); Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate. | 0.662 |
| purB | glyA | SMU_59 | SMU_1082 | Adenylosuccinate lyase; Best Blastp Hit: dbj|BAB04344.1| (AP001509) adenylosuccinate lyase [Bacillus halodurans]. | Putative serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.805 |
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