STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SMU_483Putative phosphoprotein phosphatase (pppL protein); Best Blastp Hit: emb|CAA10712.1| (AJ132604) pppL protein [Lactococcus lactis]. (247 aa)    
Predicted Functional Partners:
pknB
Putative serine/threonine protein kinase; Best Blastp Hit: emb|CAA10713.1| (AJ132604) hypothetical protein [Lactococcus lactis].
 
 
 0.999
fmt
Putative methionyl-tRNA formyltransferase; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus; Belongs to the Fmt family.
  
   0.918
adhD
Best Blastp Hit: pir||I40794 dihydrolipoamide dehydrogenase (EC 1.8.1.4) - Clostridium magnum >gi|472330|gb|AAA21748.1| (L31844) dihydrolipoamide dehydrogenase [Clostridium magnum].
  
 0.913
sunL
Putative RNA-binding Sun protein; Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA.
  
  
 0.844
priA
Primosomal replication factor Y (primosomal protein N'); Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA; Belongs to the helicase family. PriA subfamily.
  
    0.703
SMU_488
Putative hydrolase; Best Blastp Hit: emb|CAB85142.1| (AL162757) conserved hypothetical protein [Neisseria meningitidis].
   
 
 0.700
glpF
Putative glycerol uptake facilitator protein; Best Blastp Hit: sp|P22094|YDP1_LACLC HYPOTHETICAL 30.9 KDA PROTEIN IN PEPX 5'REGION (ORF1) >gi|280238|pir||B43747 hypothetical protein (pepXP 5' region) - Lactococcus lactis subsp. cremoris >gi|280244|pir||B43748 hypothetical protein (pepX 5' region) - Lactococcus lactis subsp. lactis >gi|149527|gb|AAA25231.1| (M58315) putative [Lactococcus lactis] >gi|455286|gb|AAA25206.1| (M35865) ORF1 (put.); putative [Lactococcus lactis]; Belongs to the MIP/aquaporin (TC 1.A.8) family.
    
   0.646
dnaJ
Heat shock protein DnaJ (HSP-40); Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions betwe [...]
  
   0.639
SMU_382c
Putative oxidoreductase; Best Blastp Hit: pir||S75995 hypothetical protein - Synechocystis sp. (strain PCC 6803) >gi|1001355|dbj|BAA10842.1| (D64006) auxin-induced protein [Synechocystis sp.].
    
   0.567
SMU_66
Conserved hypothetical protein; Best Blastp Hit: gb|AAG07403.1|AE004818_9 (AE004818) hypothetical protein [Pseudomonas aeruginosa].
    
   0.554
Your Current Organism:
Streptococcus mutans
NCBI taxonomy Id: 210007
Other names: S. mutans UA159, Streptococcus mutans UA159, Streptococcus mutans str. UA159
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.