node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
SMU_1309c | SMU_506 | SMU_1309c | SMU_506 | Best Blastp Hit: pir||T37628 glycerol dehydrogenase - fission yeast (Schizosaccharomyces pombe) >gi|2398802|emb|CAB11766.1| (Z99091) glycerol dehydrogenase [Schizosaccharomyces pombe]. | Putative type II restriction endonuclease; Recognizes the double-stranded unmethylated sequence GATC and cleaves before G-1; Belongs to the type II restriction enzyme DpnII family. | 0.453 |
SMU_503c | SMU_505 | SMU_503c | SMU_505 | Hypothetical protein. | Putative adenine-specific DNA methylase; Best Blastp Hit: sp|P09358|MT22_STRPN MODIFICATION METHYLASE DPNII 2 (ADENINE-SPECIFIC METHYLTRANSFERASE DPNII 2) (M.DPNII 2) >gi|6978344|gb|AAA88581.2| (M14339) DNA adenine methyltransferase [Streptococcus pneumoniae]; Belongs to the N(4)/N(6)-methyltransferase family. | 0.436 |
SMU_503c | SMU_506 | SMU_503c | SMU_506 | Hypothetical protein. | Putative type II restriction endonuclease; Recognizes the double-stranded unmethylated sequence GATC and cleaves before G-1; Belongs to the type II restriction enzyme DpnII family. | 0.436 |
SMU_503c | dam | SMU_503c | SMU_504 | Hypothetical protein. | Putative site-specific DNA-methyltransferase; Best Blastp Hit: sp|P50179|ML21_LACLC MODIFICATION METHYLASE LLADCHI A (ADENINE-SPECIFIC METHYLTRANSFERASE LLADCHI A) (M.LLADCHI A) (LLAII) >gi|794256|gb|AAB06311.1| (U16027) modification methylase LlaDCHIA [Lactococcus lactis]. | 0.436 |
SMU_505 | SMU_503c | SMU_505 | SMU_503c | Putative adenine-specific DNA methylase; Best Blastp Hit: sp|P09358|MT22_STRPN MODIFICATION METHYLASE DPNII 2 (ADENINE-SPECIFIC METHYLTRANSFERASE DPNII 2) (M.DPNII 2) >gi|6978344|gb|AAA88581.2| (M14339) DNA adenine methyltransferase [Streptococcus pneumoniae]; Belongs to the N(4)/N(6)-methyltransferase family. | Hypothetical protein. | 0.436 |
SMU_505 | SMU_506 | SMU_505 | SMU_506 | Putative adenine-specific DNA methylase; Best Blastp Hit: sp|P09358|MT22_STRPN MODIFICATION METHYLASE DPNII 2 (ADENINE-SPECIFIC METHYLTRANSFERASE DPNII 2) (M.DPNII 2) >gi|6978344|gb|AAA88581.2| (M14339) DNA adenine methyltransferase [Streptococcus pneumoniae]; Belongs to the N(4)/N(6)-methyltransferase family. | Putative type II restriction endonuclease; Recognizes the double-stranded unmethylated sequence GATC and cleaves before G-1; Belongs to the type II restriction enzyme DpnII family. | 0.985 |
SMU_505 | dam | SMU_505 | SMU_504 | Putative adenine-specific DNA methylase; Best Blastp Hit: sp|P09358|MT22_STRPN MODIFICATION METHYLASE DPNII 2 (ADENINE-SPECIFIC METHYLTRANSFERASE DPNII 2) (M.DPNII 2) >gi|6978344|gb|AAA88581.2| (M14339) DNA adenine methyltransferase [Streptococcus pneumoniae]; Belongs to the N(4)/N(6)-methyltransferase family. | Putative site-specific DNA-methyltransferase; Best Blastp Hit: sp|P50179|ML21_LACLC MODIFICATION METHYLASE LLADCHI A (ADENINE-SPECIFIC METHYLTRANSFERASE LLADCHI A) (M.LLADCHI A) (LLAII) >gi|794256|gb|AAB06311.1| (U16027) modification methylase LlaDCHIA [Lactococcus lactis]. | 0.993 |
SMU_506 | SMU_1309c | SMU_506 | SMU_1309c | Putative type II restriction endonuclease; Recognizes the double-stranded unmethylated sequence GATC and cleaves before G-1; Belongs to the type II restriction enzyme DpnII family. | Best Blastp Hit: pir||T37628 glycerol dehydrogenase - fission yeast (Schizosaccharomyces pombe) >gi|2398802|emb|CAB11766.1| (Z99091) glycerol dehydrogenase [Schizosaccharomyces pombe]. | 0.453 |
SMU_506 | SMU_503c | SMU_506 | SMU_503c | Putative type II restriction endonuclease; Recognizes the double-stranded unmethylated sequence GATC and cleaves before G-1; Belongs to the type II restriction enzyme DpnII family. | Hypothetical protein. | 0.436 |
SMU_506 | SMU_505 | SMU_506 | SMU_505 | Putative type II restriction endonuclease; Recognizes the double-stranded unmethylated sequence GATC and cleaves before G-1; Belongs to the type II restriction enzyme DpnII family. | Putative adenine-specific DNA methylase; Best Blastp Hit: sp|P09358|MT22_STRPN MODIFICATION METHYLASE DPNII 2 (ADENINE-SPECIFIC METHYLTRANSFERASE DPNII 2) (M.DPNII 2) >gi|6978344|gb|AAA88581.2| (M14339) DNA adenine methyltransferase [Streptococcus pneumoniae]; Belongs to the N(4)/N(6)-methyltransferase family. | 0.985 |
SMU_506 | dam | SMU_506 | SMU_504 | Putative type II restriction endonuclease; Recognizes the double-stranded unmethylated sequence GATC and cleaves before G-1; Belongs to the type II restriction enzyme DpnII family. | Putative site-specific DNA-methyltransferase; Best Blastp Hit: sp|P50179|ML21_LACLC MODIFICATION METHYLASE LLADCHI A (ADENINE-SPECIFIC METHYLTRANSFERASE LLADCHI A) (M.LLADCHI A) (LLAII) >gi|794256|gb|AAB06311.1| (U16027) modification methylase LlaDCHIA [Lactococcus lactis]. | 0.965 |
SMU_506 | hup | SMU_506 | SMU_589 | Putative type II restriction endonuclease; Recognizes the double-stranded unmethylated sequence GATC and cleaves before G-1; Belongs to the type II restriction enzyme DpnII family. | Putative DNA-binding protein; Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions. Seems also to act as a fortuitous virulence factor in delayed sequelae by binding to heparan sulfate-proteoglycans in the extracellular matrix of target organs and acting as a nidus for in situ immune complex formation. | 0.625 |
SMU_506 | metB | SMU_506 | SMU_1675 | Putative type II restriction endonuclease; Recognizes the double-stranded unmethylated sequence GATC and cleaves before G-1; Belongs to the type II restriction enzyme DpnII family. | Putative cystathionine gamma-synthase; Best Blastp Hit: pir||G64047 cystathionine gamma-lyase homolog - Haemophilus influenzae (strain Rd KW20) >gi|1573037|gb|AAC21764.1| (U32694) cystathionine gamma-synthase (metB) [Haemophilus influenzae Rd] 4.4.1.1 cystathionine gamma-lyase or cystathionine beta-lyases 4.4.8.1. | 0.544 |
SMU_506 | ruvA | SMU_506 | SMU_2088 | Putative type II restriction endonuclease; Recognizes the double-stranded unmethylated sequence GATC and cleaves before G-1; Belongs to the type II restriction enzyme DpnII family. | Putative Holliday junction DNA helicase RuvA; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB. | 0.621 |
dam | SMU_503c | SMU_504 | SMU_503c | Putative site-specific DNA-methyltransferase; Best Blastp Hit: sp|P50179|ML21_LACLC MODIFICATION METHYLASE LLADCHI A (ADENINE-SPECIFIC METHYLTRANSFERASE LLADCHI A) (M.LLADCHI A) (LLAII) >gi|794256|gb|AAB06311.1| (U16027) modification methylase LlaDCHIA [Lactococcus lactis]. | Hypothetical protein. | 0.436 |
dam | SMU_505 | SMU_504 | SMU_505 | Putative site-specific DNA-methyltransferase; Best Blastp Hit: sp|P50179|ML21_LACLC MODIFICATION METHYLASE LLADCHI A (ADENINE-SPECIFIC METHYLTRANSFERASE LLADCHI A) (M.LLADCHI A) (LLAII) >gi|794256|gb|AAB06311.1| (U16027) modification methylase LlaDCHIA [Lactococcus lactis]. | Putative adenine-specific DNA methylase; Best Blastp Hit: sp|P09358|MT22_STRPN MODIFICATION METHYLASE DPNII 2 (ADENINE-SPECIFIC METHYLTRANSFERASE DPNII 2) (M.DPNII 2) >gi|6978344|gb|AAA88581.2| (M14339) DNA adenine methyltransferase [Streptococcus pneumoniae]; Belongs to the N(4)/N(6)-methyltransferase family. | 0.993 |
dam | SMU_506 | SMU_504 | SMU_506 | Putative site-specific DNA-methyltransferase; Best Blastp Hit: sp|P50179|ML21_LACLC MODIFICATION METHYLASE LLADCHI A (ADENINE-SPECIFIC METHYLTRANSFERASE LLADCHI A) (M.LLADCHI A) (LLAII) >gi|794256|gb|AAB06311.1| (U16027) modification methylase LlaDCHIA [Lactococcus lactis]. | Putative type II restriction endonuclease; Recognizes the double-stranded unmethylated sequence GATC and cleaves before G-1; Belongs to the type II restriction enzyme DpnII family. | 0.965 |
hup | SMU_506 | SMU_589 | SMU_506 | Putative DNA-binding protein; Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions. Seems also to act as a fortuitous virulence factor in delayed sequelae by binding to heparan sulfate-proteoglycans in the extracellular matrix of target organs and acting as a nidus for in situ immune complex formation. | Putative type II restriction endonuclease; Recognizes the double-stranded unmethylated sequence GATC and cleaves before G-1; Belongs to the type II restriction enzyme DpnII family. | 0.625 |
hup | ruvA | SMU_589 | SMU_2088 | Putative DNA-binding protein; Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions. Seems also to act as a fortuitous virulence factor in delayed sequelae by binding to heparan sulfate-proteoglycans in the extracellular matrix of target organs and acting as a nidus for in situ immune complex formation. | Putative Holliday junction DNA helicase RuvA; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB. | 0.472 |
metB | SMU_506 | SMU_1675 | SMU_506 | Putative cystathionine gamma-synthase; Best Blastp Hit: pir||G64047 cystathionine gamma-lyase homolog - Haemophilus influenzae (strain Rd KW20) >gi|1573037|gb|AAC21764.1| (U32694) cystathionine gamma-synthase (metB) [Haemophilus influenzae Rd] 4.4.1.1 cystathionine gamma-lyase or cystathionine beta-lyases 4.4.8.1. | Putative type II restriction endonuclease; Recognizes the double-stranded unmethylated sequence GATC and cleaves before G-1; Belongs to the type II restriction enzyme DpnII family. | 0.544 |