node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
SMU_1657c | citB | SMU_1657c | SMU_670 | Putative nitrogen regulatory protein PII; Best Blastp Hit: emb|CAB94814.1| (AJ245582) hypothetical protein [Streptococcus thermophilus]. | Aconitate hydratase; Involved in the catabolism of short chain fatty acids (SCFA) via the tricarboxylic acid (TCA)(acetyl degradation route) and probably the 2-methylcitrate cycle I (propionate degradation route). Catalyzes the reversible isomerization of citrate to isocitrate via cis- aconitate. Could catalyze the hydration of 2-methyl-cis-aconitate to yield (2R,3S)-2-methylisocitrate. The apo form of AcnA functions as a RNA-binding regulatory protein. | 0.770 |
SMU_1657c | citZ | SMU_1657c | SMU_671 | Putative nitrogen regulatory protein PII; Best Blastp Hit: emb|CAB94814.1| (AJ245582) hypothetical protein [Streptococcus thermophilus]. | Citrate synthase; Best Blastp Hit: sp|Q59939|CISZ_STRMU CITRATE SYNTHASE >gi|1421813|gb|AAC44825.1| (U62799) citrate synthase [Streptococcus mutans]. | 0.629 |
SMU_1657c | idh | SMU_1657c | SMU_672 | Putative nitrogen regulatory protein PII; Best Blastp Hit: emb|CAB94814.1| (AJ245582) hypothetical protein [Streptococcus thermophilus]. | Best Blastp Hit: sp|Q59940|IDH_STRMU ISOCITRATE DEHYDROGENASE [NADP] (OXALOSUCCINATE DECARBOXYLASE) (IDH) (NADP+-SPECIFIC ICDH) (IDP) >gi|1421814|gb|AAC44826.1| (U62799) isocitrate dehydrogenase [Streptococcus mutans]. | 0.725 |
SMU_1657c | nrgA | SMU_1657c | SMU_1658 | Putative nitrogen regulatory protein PII; Best Blastp Hit: emb|CAB94814.1| (AJ245582) hypothetical protein [Streptococcus thermophilus]. | Putative ammonium transporter, NrgA protein; Best Blastp Hit: gb|AAF73971.1| (U81166) NrgA-like protein [Lactococcus lactis subsp. cremoris]. | 0.999 |
citB | SMU_1657c | SMU_670 | SMU_1657c | Aconitate hydratase; Involved in the catabolism of short chain fatty acids (SCFA) via the tricarboxylic acid (TCA)(acetyl degradation route) and probably the 2-methylcitrate cycle I (propionate degradation route). Catalyzes the reversible isomerization of citrate to isocitrate via cis- aconitate. Could catalyze the hydration of 2-methyl-cis-aconitate to yield (2R,3S)-2-methylisocitrate. The apo form of AcnA functions as a RNA-binding regulatory protein. | Putative nitrogen regulatory protein PII; Best Blastp Hit: emb|CAB94814.1| (AJ245582) hypothetical protein [Streptococcus thermophilus]. | 0.770 |
citB | citZ | SMU_670 | SMU_671 | Aconitate hydratase; Involved in the catabolism of short chain fatty acids (SCFA) via the tricarboxylic acid (TCA)(acetyl degradation route) and probably the 2-methylcitrate cycle I (propionate degradation route). Catalyzes the reversible isomerization of citrate to isocitrate via cis- aconitate. Could catalyze the hydration of 2-methyl-cis-aconitate to yield (2R,3S)-2-methylisocitrate. The apo form of AcnA functions as a RNA-binding regulatory protein. | Citrate synthase; Best Blastp Hit: sp|Q59939|CISZ_STRMU CITRATE SYNTHASE >gi|1421813|gb|AAC44825.1| (U62799) citrate synthase [Streptococcus mutans]. | 0.999 |
citB | fabM | SMU_670 | SMU_1746c | Aconitate hydratase; Involved in the catabolism of short chain fatty acids (SCFA) via the tricarboxylic acid (TCA)(acetyl degradation route) and probably the 2-methylcitrate cycle I (propionate degradation route). Catalyzes the reversible isomerization of citrate to isocitrate via cis- aconitate. Could catalyze the hydration of 2-methyl-cis-aconitate to yield (2R,3S)-2-methylisocitrate. The apo form of AcnA functions as a RNA-binding regulatory protein. | Putative enoyl-CoA hydratase; Catalyzes the isomerization of trans-2-decenoyl-ACP to cis-3- decenoyl-ACP (By similarity). Required for survival at low pH. | 0.791 |
citB | idh | SMU_670 | SMU_672 | Aconitate hydratase; Involved in the catabolism of short chain fatty acids (SCFA) via the tricarboxylic acid (TCA)(acetyl degradation route) and probably the 2-methylcitrate cycle I (propionate degradation route). Catalyzes the reversible isomerization of citrate to isocitrate via cis- aconitate. Could catalyze the hydration of 2-methyl-cis-aconitate to yield (2R,3S)-2-methylisocitrate. The apo form of AcnA functions as a RNA-binding regulatory protein. | Best Blastp Hit: sp|Q59940|IDH_STRMU ISOCITRATE DEHYDROGENASE [NADP] (OXALOSUCCINATE DECARBOXYLASE) (IDH) (NADP+-SPECIFIC ICDH) (IDP) >gi|1421814|gb|AAC44826.1| (U62799) isocitrate dehydrogenase [Streptococcus mutans]. | 0.999 |
citB | nrgA | SMU_670 | SMU_1658 | Aconitate hydratase; Involved in the catabolism of short chain fatty acids (SCFA) via the tricarboxylic acid (TCA)(acetyl degradation route) and probably the 2-methylcitrate cycle I (propionate degradation route). Catalyzes the reversible isomerization of citrate to isocitrate via cis- aconitate. Could catalyze the hydration of 2-methyl-cis-aconitate to yield (2R,3S)-2-methylisocitrate. The apo form of AcnA functions as a RNA-binding regulatory protein. | Putative ammonium transporter, NrgA protein; Best Blastp Hit: gb|AAF73971.1| (U81166) NrgA-like protein [Lactococcus lactis subsp. cremoris]. | 0.756 |
citB | rl19 | SMU_670 | SMU_1288 | Aconitate hydratase; Involved in the catabolism of short chain fatty acids (SCFA) via the tricarboxylic acid (TCA)(acetyl degradation route) and probably the 2-methylcitrate cycle I (propionate degradation route). Catalyzes the reversible isomerization of citrate to isocitrate via cis- aconitate. Could catalyze the hydration of 2-methyl-cis-aconitate to yield (2R,3S)-2-methylisocitrate. The apo form of AcnA functions as a RNA-binding regulatory protein. | 50S ribosomal protein L19; This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site. | 0.749 |
citB | rl5 | SMU_670 | SMU_2015 | Aconitate hydratase; Involved in the catabolism of short chain fatty acids (SCFA) via the tricarboxylic acid (TCA)(acetyl degradation route) and probably the 2-methylcitrate cycle I (propionate degradation route). Catalyzes the reversible isomerization of citrate to isocitrate via cis- aconitate. Could catalyze the hydration of 2-methyl-cis-aconitate to yield (2R,3S)-2-methylisocitrate. The apo form of AcnA functions as a RNA-binding regulatory protein. | 50S ribosomal protein L5; This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs. | 0.721 |
citB | rpmB | SMU_670 | SMU_120 | Aconitate hydratase; Involved in the catabolism of short chain fatty acids (SCFA) via the tricarboxylic acid (TCA)(acetyl degradation route) and probably the 2-methylcitrate cycle I (propionate degradation route). Catalyzes the reversible isomerization of citrate to isocitrate via cis- aconitate. Could catalyze the hydration of 2-methyl-cis-aconitate to yield (2R,3S)-2-methylisocitrate. The apo form of AcnA functions as a RNA-binding regulatory protein. | 50S ribosomal protein L28; Best Blastp Hit: dbj|BAB06219.1| (AP001515) ribosomal protein L28 [Bacillus halodurans]; Belongs to the bacterial ribosomal protein bL28 family. | 0.720 |
citB | rpmJ | SMU_670 | SMU_2003a | Aconitate hydratase; Involved in the catabolism of short chain fatty acids (SCFA) via the tricarboxylic acid (TCA)(acetyl degradation route) and probably the 2-methylcitrate cycle I (propionate degradation route). Catalyzes the reversible isomerization of citrate to isocitrate via cis- aconitate. Could catalyze the hydration of 2-methyl-cis-aconitate to yield (2R,3S)-2-methylisocitrate. The apo form of AcnA functions as a RNA-binding regulatory protein. | 50S ribosomal protein L36; Belongs to the bacterial ribosomal protein bL36 family. | 0.710 |
citB | sod | SMU_670 | SMU_629 | Aconitate hydratase; Involved in the catabolism of short chain fatty acids (SCFA) via the tricarboxylic acid (TCA)(acetyl degradation route) and probably the 2-methylcitrate cycle I (propionate degradation route). Catalyzes the reversible isomerization of citrate to isocitrate via cis- aconitate. Could catalyze the hydration of 2-methyl-cis-aconitate to yield (2R,3S)-2-methylisocitrate. The apo form of AcnA functions as a RNA-binding regulatory protein. | Putative manganese-type superoxide dismutase, Fe/Mn-SOD; Destroys superoxide anion radicals which are normally produced within the cells and which are toxic to biological systems. | 0.781 |
citZ | SMU_1657c | SMU_671 | SMU_1657c | Citrate synthase; Best Blastp Hit: sp|Q59939|CISZ_STRMU CITRATE SYNTHASE >gi|1421813|gb|AAC44825.1| (U62799) citrate synthase [Streptococcus mutans]. | Putative nitrogen regulatory protein PII; Best Blastp Hit: emb|CAB94814.1| (AJ245582) hypothetical protein [Streptococcus thermophilus]. | 0.629 |
citZ | citB | SMU_671 | SMU_670 | Citrate synthase; Best Blastp Hit: sp|Q59939|CISZ_STRMU CITRATE SYNTHASE >gi|1421813|gb|AAC44825.1| (U62799) citrate synthase [Streptococcus mutans]. | Aconitate hydratase; Involved in the catabolism of short chain fatty acids (SCFA) via the tricarboxylic acid (TCA)(acetyl degradation route) and probably the 2-methylcitrate cycle I (propionate degradation route). Catalyzes the reversible isomerization of citrate to isocitrate via cis- aconitate. Could catalyze the hydration of 2-methyl-cis-aconitate to yield (2R,3S)-2-methylisocitrate. The apo form of AcnA functions as a RNA-binding regulatory protein. | 0.999 |
citZ | fabM | SMU_671 | SMU_1746c | Citrate synthase; Best Blastp Hit: sp|Q59939|CISZ_STRMU CITRATE SYNTHASE >gi|1421813|gb|AAC44825.1| (U62799) citrate synthase [Streptococcus mutans]. | Putative enoyl-CoA hydratase; Catalyzes the isomerization of trans-2-decenoyl-ACP to cis-3- decenoyl-ACP (By similarity). Required for survival at low pH. | 0.609 |
citZ | idh | SMU_671 | SMU_672 | Citrate synthase; Best Blastp Hit: sp|Q59939|CISZ_STRMU CITRATE SYNTHASE >gi|1421813|gb|AAC44825.1| (U62799) citrate synthase [Streptococcus mutans]. | Best Blastp Hit: sp|Q59940|IDH_STRMU ISOCITRATE DEHYDROGENASE [NADP] (OXALOSUCCINATE DECARBOXYLASE) (IDH) (NADP+-SPECIFIC ICDH) (IDP) >gi|1421814|gb|AAC44826.1| (U62799) isocitrate dehydrogenase [Streptococcus mutans]. | 0.999 |
citZ | nrgA | SMU_671 | SMU_1658 | Citrate synthase; Best Blastp Hit: sp|Q59939|CISZ_STRMU CITRATE SYNTHASE >gi|1421813|gb|AAC44825.1| (U62799) citrate synthase [Streptococcus mutans]. | Putative ammonium transporter, NrgA protein; Best Blastp Hit: gb|AAF73971.1| (U81166) NrgA-like protein [Lactococcus lactis subsp. cremoris]. | 0.835 |
fabM | citB | SMU_1746c | SMU_670 | Putative enoyl-CoA hydratase; Catalyzes the isomerization of trans-2-decenoyl-ACP to cis-3- decenoyl-ACP (By similarity). Required for survival at low pH. | Aconitate hydratase; Involved in the catabolism of short chain fatty acids (SCFA) via the tricarboxylic acid (TCA)(acetyl degradation route) and probably the 2-methylcitrate cycle I (propionate degradation route). Catalyzes the reversible isomerization of citrate to isocitrate via cis- aconitate. Could catalyze the hydration of 2-methyl-cis-aconitate to yield (2R,3S)-2-methylisocitrate. The apo form of AcnA functions as a RNA-binding regulatory protein. | 0.791 |