STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
idhBest Blastp Hit: sp|Q59940|IDH_STRMU ISOCITRATE DEHYDROGENASE [NADP] (OXALOSUCCINATE DECARBOXYLASE) (IDH) (NADP+-SPECIFIC ICDH) (IDP) >gi|1421814|gb|AAC44826.1| (U62799) isocitrate dehydrogenase [Streptococcus mutans]. (393 aa)    
Predicted Functional Partners:
citB
Aconitate hydratase; Involved in the catabolism of short chain fatty acids (SCFA) via the tricarboxylic acid (TCA)(acetyl degradation route) and probably the 2-methylcitrate cycle I (propionate degradation route). Catalyzes the reversible isomerization of citrate to isocitrate via cis- aconitate. Could catalyze the hydration of 2-methyl-cis-aconitate to yield (2R,3S)-2-methylisocitrate. The apo form of AcnA functions as a RNA-binding regulatory protein.
  
 0.999
citZ
Citrate synthase; Best Blastp Hit: sp|Q59939|CISZ_STRMU CITRATE SYNTHASE >gi|1421813|gb|AAC44825.1| (U62799) citrate synthase [Streptococcus mutans].
 
 
 0.999
SMU_913
Best Blastp Hit: dbj|BAB05820.1| (AP001514) NADP-specific glutamate dehydrogenase [Bacillus halodurans]; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
   
 0.949
gltA
Best Blastp Hit: dbj|BAB05447.1| (AP001513) glutamate synthase (large subunit) [Bacillus halodurans].
  
 
 0.937
ldh
Lactate dehydrogenase; Catalyzes the conversion of lactate to pyruvate. Belongs to the LDH/MDH superfamily. LDH family.
  
 
 0.897
argH
Argininosuccinate lyase; Best Blastp Hit: dbj|BAB06905.1| (AP001518) argininosuccinate lyase [Bacillus halodurans].
   
 
 0.837
purB
Adenylosuccinate lyase; Best Blastp Hit: dbj|BAB04344.1| (AP001509) adenylosuccinate lyase [Bacillus halodurans].
  
 
  0.835
cnhA
Putative carbon-nitrogen hydrolase; Best Blastp Hit: pir||E69863 conserved hypothetical protein ykrU - Bacillus subtilis >gi|2633728|emb|CAB13230.1| (Z99111) similar to hypothetical proteins [Bacillus subtilis].
  
 
  0.834
yfbQ
Putative aminotransferase; Best Blastp Hit: sp|P71348|YFBQ_HAEIN PROBABLE AMINOTRANSFERASE HI0286 >gi|1573250|gb|AAC21948.1| (U32714) aminotransferase## [Haemophilus influenzae Rd].
   
 0.825
SMU_2127
Best Blastp Hit: gb|AAD19405.1| (AF102543) succinic semialdehyde dehydrogenase [Zymomonas mobilis]; Belongs to the aldehyde dehydrogenase family.
   
 0.821
Your Current Organism:
Streptococcus mutans
NCBI taxonomy Id: 210007
Other names: S. mutans UA159, Streptococcus mutans UA159, Streptococcus mutans str. UA159
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