STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
fruIBest Blastp Hit: dbj|BAB04547.1| (AP001510) PTS system, fructose-specific enzyme II, BC component [Bacillus halodurans]. (655 aa)    
Predicted Functional Partners:
pfkB
Putative fructose-1-phosphate kinase; Best Blastp Hit: sp|O31714|K1PF_BACSU 1-PHOSPHOFRUCTOKINASE (FRUCTOSE 1-PHOSPHATE KINASE) >gi|7434216|pir||A69627 fructose 1-phosphate kinase fruB - Bacillus subtilis >gi|2633810|emb|CAB13312.1| (Z99111) fructose-1-phosphate kinase [Bacillus subtilis] >gi|3282124|gb|AAC24914.1| (AF012285) fructose-1-phosphate kinase [Bacillus subtilis]; Belongs to the carbohydrate kinase PfkB family. LacC subfamily.
 
 
 0.999
fruP
Putative fructose-1-phosphate kinase; Best Blastp Hit: dbj|BAB04546.1| (AP001510) fructose 1-phosphate kinase [Bacillus halodurans]; Belongs to the carbohydrate kinase PfkB family. LacC subfamily.
 
 
 0.998
fruD
Best Blastp Hit: pir||H69626 PTS fructose-specific enzyme IIBC component fruA - Bacillus subtilis >gi|2633811|emb|CAB13313.1| (Z99111) phosphotransferase system (PTS) fructose-specific enzyme IIBC component [Bacillus subtilis] >gi|3282125|gb|AAC24915.1| (AF012285) fructose PTS IIABC [Bacillus subtilis].
 
0.992
ptsH
Phosphoenolpyruvate:sugar phosphotransferase system HPr; General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The phosphoryl group from phosphoenolpyruvate (PEP) is transferred to the phosphoryl carrier protein HPr by enzyme I. Phospho-HPr then transfers it to the PTS EIIA domain.
  
 
 0.990
lacC
Tagatose-6-phosphate kinase; Best Blastp Hit: sp|P26421|LACC_STRMU TAGATOSE-6-PHOSPHATE KINASE (PHOSPHOTAGATOKINASE) >gi|322119|pir||E43258 tagatose-6-phosphate kinase - Streptococcus mutans >gi|153675|gb|AAA26906.1| (M80797) tagatose 6-P kinase [Streptococcus mutans]; Belongs to the carbohydrate kinase PfkB family. LacC subfamily.
 
  
 0.976
mtlA2
PTS system, mannitol-specific enzyme IIA; The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The enzyme II CmtAB PTS system is involved in D-mannitol transport.
 
  
 0.972
fruR
Putative transcriptional regulator of sugar metabolism; Best Blastp Hit: dbj|BAB04545.1| (AP001510) transcriptional repressor [Bacillus halodurans].
 
  
 0.972
ptsG
Putative PTS system, glucose-specific IIABC component; Best Blastp Hit: gb|AAD00281.1| (U78600) putative ptsG## protein [Streptococcus mutans].
 
  
 0.969
fruC
Best Blastp Hit: dbj|BAB04547.1| (AP001510) PTS system, fructose-specific enzyme II, BC component [Bacillus halodurans].
 
 
0.962
pttB
Best Blastp Hit: pir||B82263 PTS system, trehalose-specific IIBC component VC0910 [imported] - Vibrio cholerae (group O1 strain N16961) >gi|9655367|gb|AAF94072.1| (AE004175) PTS system, trehalose-specific IIBC component [Vibrio cholerae].
  
  
 0.953
Your Current Organism:
Streptococcus mutans
NCBI taxonomy Id: 210007
Other names: S. mutans UA159, Streptococcus mutans UA159, Streptococcus mutans str. UA159
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