STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
galKGalactokinase, GalK; Catalyzes the transfer of the gamma-phosphate of ATP to D- galactose to form alpha-D-galactose-1-phosphate (Gal-1-P). Belongs to the GHMP kinase family. GalK subfamily. (390 aa)    
Predicted Functional Partners:
galT
galactose-1-P-uridyl transferase, GalT; Best Blastp Hit: sp|P96994|GAL7_STRMU GALACTOSE-1-PHOSPHATE URIDYLYLTRANSFERASE (GAL-1-P URIDYLYLTRANSFERASE) >gi|7448853|pir||JC5312 UTP--hexose-1-phosphate uridylyltransferase (EC 2.7.7.10) - Streptococcus mutans >gi|1877423|gb|AAB49737.1| (U21942) galactose-1-P-uridyl transferase [Streptococcus mutans].
 
 
 0.999
galE
UDP-galactose 4-epimerase, GalE; Involved in the metabolism of galactose. Catalyzes the conversion of UDP-galactose (UDP-Gal) to UDP-glucose (UDP-Glc) through a mechanism involving the transient reduction of NAD (By similarity).
 
 
 0.986
galR
Best Blastp Hit: pir||JC5310 galactose repressor - Streptococcus mutans.
 
  
 0.982
lacX
Best Blastp Hit: sp|P23496|LAXP_LACLA LACX PROTEIN, PLASMID >gi|97946|pir||D23696 lacX protein - Lactococcus lactis >gi|149413|gb|AAA25184.1| (M60447) ORF [Lactococcus lactis].
 
 
 0.855
lacA
Best Blastp Hit: sp|P26423|LACA_STRMU GALACTOSE-6-PHOSPHATE ISOMERASE LACA SUBUNIT >gi|322117|pir||C43258 galactoside O-acetyltransferase (EC 2.3.1.18) - Streptococcus mutans >gi|153673|gb|AAA26904.1| (M80797) galactosidase acetyltransferase [Streptococcus mutans].
  
  
 0.826
lacD
Tagatose-1,6-bisphosphate aldolase; Best Blastp Hit: sp|P26425|LACD_STRMU TAGATOSE 1,6-DIPHOSPHATE ALDOLASE (TAGATOSE-BISPHOSPHATE ALDOLASE) (D-TAGATOSE-1,6-BISPHOSPHATE ALDOLASE) >gi|322120|pir||F43258 tagatose-1,6-bisphosphate aldolase homolog LacD - Streptococcus mutans >gi|153676|gb|AAA26907.1| (M80797) tagatose 1,6-aldolase [Streptococcus mutans].
   
  
 0.823
lacB
Best Blastp Hit: pir||D43258 galactose-6-phosphate isomerase subunit LacB - Streptococcus mutans.
  
  
 0.822
SMU_2065
Best Blastp Hit: sp|P55180|GALE_BACSU UDP-GLUCOSE 4-EPIMERASE (GALACTOWALDENASE) (UDP-GALACTOSE 4-EPIMERASE) >gi|7437225|pir||D69628 UDPglucose 4-epimerase (EC 5.1.3.2) - Bacillus subtilis >gi|1429254|emb|CAA67713.1| (X99339) UDP-glucose 4-epimerase [Bacillus subtilis] >gi|1783241|dbj|BAA11718.1| (D83026) highly homologous to UDP-glucose 4-epimerases (SwissProt:GALE_HAEIN and GALE_ECOLI); hypothetical [Bacillus subtilis] >gi|2636421|emb|CAB15912.1| (Z99123) UDP-glucose 4-epimerase [Bacillus subtilis]; Belongs to the NAD(P)-dependent epimerase/dehydratase family.
  
 
 0.808
lacC
Tagatose-6-phosphate kinase; Best Blastp Hit: sp|P26421|LACC_STRMU TAGATOSE-6-PHOSPHATE KINASE (PHOSPHOTAGATOKINASE) >gi|322119|pir||E43258 tagatose-6-phosphate kinase - Streptococcus mutans >gi|153675|gb|AAA26906.1| (M80797) tagatose 6-P kinase [Streptococcus mutans]; Belongs to the carbohydrate kinase PfkB family. LacC subfamily.
   
  
 0.789
agaL
Alpha-galactosidase; Best Blastp Hit: sp|P27756|AGAL_STRMU ALPHA-GALACTOSIDASE (MELIBIASE) >gi|322116|pir||A44819 alpha-galactosidase (EC 3.2.1.22) - Streptococcus mutans >gi|153736|gb|AAA26933.1| (M77351) a-galactosidase [Streptococcus mutans]; Belongs to the glycosyl hydrolase 36 family.
 
  
 0.726
Your Current Organism:
Streptococcus mutans
NCBI taxonomy Id: 210007
Other names: S. mutans UA159, Streptococcus mutans UA159, Streptococcus mutans str. UA159
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