STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
galTgalactose-1-P-uridyl transferase, GalT; Best Blastp Hit: sp|P96994|GAL7_STRMU GALACTOSE-1-PHOSPHATE URIDYLYLTRANSFERASE (GAL-1-P URIDYLYLTRANSFERASE) >gi|7448853|pir||JC5312 UTP--hexose-1-phosphate uridylyltransferase (EC 2.7.7.10) - Streptococcus mutans >gi|1877423|gb|AAB49737.1| (U21942) galactose-1-P-uridyl transferase [Streptococcus mutans]. (491 aa)    
Predicted Functional Partners:
galK
Galactokinase, GalK; Catalyzes the transfer of the gamma-phosphate of ATP to D- galactose to form alpha-D-galactose-1-phosphate (Gal-1-P). Belongs to the GHMP kinase family. GalK subfamily.
 
 
 0.999
galE
UDP-galactose 4-epimerase, GalE; Involved in the metabolism of galactose. Catalyzes the conversion of UDP-galactose (UDP-Gal) to UDP-glucose (UDP-Glc) through a mechanism involving the transient reduction of NAD (By similarity).
  
 
 0.996
SMU_2065
Best Blastp Hit: sp|P55180|GALE_BACSU UDP-GLUCOSE 4-EPIMERASE (GALACTOWALDENASE) (UDP-GALACTOSE 4-EPIMERASE) >gi|7437225|pir||D69628 UDPglucose 4-epimerase (EC 5.1.3.2) - Bacillus subtilis >gi|1429254|emb|CAA67713.1| (X99339) UDP-glucose 4-epimerase [Bacillus subtilis] >gi|1783241|dbj|BAA11718.1| (D83026) highly homologous to UDP-glucose 4-epimerases (SwissProt:GALE_HAEIN and GALE_ECOLI); hypothetical [Bacillus subtilis] >gi|2636421|emb|CAB15912.1| (Z99123) UDP-glucose 4-epimerase [Bacillus subtilis]; Belongs to the NAD(P)-dependent epimerase/dehydratase family.
  
 
 0.973
msmF
Multiple sugar-binding ABC transporter, permease protein MsmF; Involved in a binding protein-dependent transport system responsible for the uptake of melibiose, raffinose and isomaltotriose; Belongs to the binding-protein-dependent transport system permease family. MalFG subfamily.
  
    0.924
SMU_322c
Best Blastp Hit: dbj|BAA28714.1| (AB001562) glucose-1-phosphate uridylyltransferase [Streptococcus mutans].
     
 0.919
msmG
Multiple sugar-binding ABC transporter, permease protein MsmG; Involved in a binding protein-dependent transport system responsible for the uptake of melibiose, raffinose and isomaltotriose; Belongs to the binding-protein-dependent transport system permease family. MalFG subfamily.
  
    0.917
galR
Best Blastp Hit: pir||JC5310 galactose repressor - Streptococcus mutans.
 
  
 0.907
lacE
PTS system, lactose-specific enzyme IIBC EIIBC-LAC); The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The enzyme II LacEF PTS system is involved in lactose transport.
 
  
 0.819
gtfA
Sucrose phosphorylase, GtfA; Intracellular catabolism of sucrose. Production of extracellular glucans, that are thought to play a key role in the development of the dental plaque because of their ability to adhere to smooth surfaces and mediate the aggregation of bacterial cells and food debris.
  
  
 0.810
msmK
Multiple sugar-binding ABC transporter, ATP-binding protein, MsmK; Involved in a binding protein-dependent transport system responsible for the uptake of melibiose, raffinose and isomaltotriose. Probably responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily.
  
    0.771
Your Current Organism:
Streptococcus mutans
NCBI taxonomy Id: 210007
Other names: S. mutans UA159, Streptococcus mutans UA159, Streptococcus mutans str. UA159
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