node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
SMU_1046c | folE | SMU_1046c | SMU_968 | Putative GTP pyrophosphokinase; Best Blastp Hit: dbj|BAB06568.1| (AP001516) GTP pyrophosphokinase [Bacillus halodurans]. | Best Blastp Hit: sp|O33723|GCH1_STRPY GTP CYCLOHYDROLASE I (GTP-CH-I) >gi|3242315|emb|CAA04237.1| (AJ000685) GTP cyclohydrolase [Streptococcus pyogenes]. | 0.800 |
SMU_1046c | nrdD | SMU_1046c | SMU_2074 | Putative GTP pyrophosphokinase; Best Blastp Hit: dbj|BAB06568.1| (AP001516) GTP pyrophosphokinase [Bacillus halodurans]. | Best Blastp Hit: gb|AAD00215.1| (U73336) anaerobic ribonucleotide reductase [Lactococcus lactis subsp. cremoris]. | 0.900 |
SMU_1046c | pykF | SMU_1046c | SMU_1190 | Putative GTP pyrophosphokinase; Best Blastp Hit: dbj|BAB06568.1| (AP001516) GTP pyrophosphokinase [Bacillus halodurans]. | Pyruvate kinase; Best Blastp Hit: gb|AAF25804.1|AF172173_2 (AF172173) pyruvate kinase [Streptococcus thermophilus]. | 0.901 |
SMU_1046c | relA | SMU_1046c | SMU_2044 | Putative GTP pyrophosphokinase; Best Blastp Hit: dbj|BAB06568.1| (AP001516) GTP pyrophosphokinase [Bacillus halodurans]. | Putative stringent response protein, ppGpp synthetase; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | 0.908 |
SMU_917c | folE | SMU_917c | SMU_968 | Putative 6-pyruvoyl tetrahydropterin synthase; Best Blastp Hit: pir||C72425 hypothetical protein TM0038 - Thermotoga maritima (strain MSB8) >gi|4980523|gb|AAD35132.1|AE001691_6 (AE001691) 6-pyruvoyl tetrahydrobiopterin synthase, putative [Thermotoga maritima]. | Best Blastp Hit: sp|O33723|GCH1_STRPY GTP CYCLOHYDROLASE I (GTP-CH-I) >gi|3242315|emb|CAA04237.1| (AJ000685) GTP cyclohydrolase [Streptococcus pyogenes]. | 0.988 |
asd | folE | SMU_989 | SMU_968 | Aspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. | Best Blastp Hit: sp|O33723|GCH1_STRPY GTP CYCLOHYDROLASE I (GTP-CH-I) >gi|3242315|emb|CAA04237.1| (AJ000685) GTP cyclohydrolase [Streptococcus pyogenes]. | 0.830 |
asd | pykF | SMU_989 | SMU_1190 | Aspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. | Pyruvate kinase; Best Blastp Hit: gb|AAF25804.1|AF172173_2 (AF172173) pyruvate kinase [Streptococcus thermophilus]. | 0.572 |
folA | folC | SMU_970 | SMU_967 | Putative dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | Putative folyl-polyglutamate synthetase; Best Blastp Hit: sp|Q05865|FOLC_BACSU FOLYLPOLYGLUTAMATE SYNTHASE (FOLYLPOLY-GAMMA-GLUTAMATE SYNTHETASE) (FPGS) >gi|421496|pir||B40646 folyl-polyglutamate synthetase folC - Bacillus subtilis >gi|142936|gb|AAB59021.1| (L04520) folyl-polyglutamate synthetase [Bacillus subtilis] >gi|2635273|emb|CAB14768.1| (Z99118) folyl-polyglutamate synthetase [Bacillus subtilis]. | 0.860 |
folA | folE | SMU_970 | SMU_968 | Putative dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | Best Blastp Hit: sp|O33723|GCH1_STRPY GTP CYCLOHYDROLASE I (GTP-CH-I) >gi|3242315|emb|CAA04237.1| (AJ000685) GTP cyclohydrolase [Streptococcus pyogenes]. | 0.986 |
folA | folK | SMU_970 | SMU_971 | Putative dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | Putative 2-amino-4-hydroxy-6-hydroxymethylpteridine pyrophosphokinase; Best Blastp Hit: dbj|BAB03814.1| (AP001507) 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase [Bacillus halodurans]. | 0.999 |
folA | folP | SMU_970 | SMU_969 | Putative dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. | 0.999 |
folC | folA | SMU_967 | SMU_970 | Putative folyl-polyglutamate synthetase; Best Blastp Hit: sp|Q05865|FOLC_BACSU FOLYLPOLYGLUTAMATE SYNTHASE (FOLYLPOLY-GAMMA-GLUTAMATE SYNTHETASE) (FPGS) >gi|421496|pir||B40646 folyl-polyglutamate synthetase folC - Bacillus subtilis >gi|142936|gb|AAB59021.1| (L04520) folyl-polyglutamate synthetase [Bacillus subtilis] >gi|2635273|emb|CAB14768.1| (Z99118) folyl-polyglutamate synthetase [Bacillus subtilis]. | Putative dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | 0.860 |
folC | folE | SMU_967 | SMU_968 | Putative folyl-polyglutamate synthetase; Best Blastp Hit: sp|Q05865|FOLC_BACSU FOLYLPOLYGLUTAMATE SYNTHASE (FOLYLPOLY-GAMMA-GLUTAMATE SYNTHETASE) (FPGS) >gi|421496|pir||B40646 folyl-polyglutamate synthetase folC - Bacillus subtilis >gi|142936|gb|AAB59021.1| (L04520) folyl-polyglutamate synthetase [Bacillus subtilis] >gi|2635273|emb|CAB14768.1| (Z99118) folyl-polyglutamate synthetase [Bacillus subtilis]. | Best Blastp Hit: sp|O33723|GCH1_STRPY GTP CYCLOHYDROLASE I (GTP-CH-I) >gi|3242315|emb|CAA04237.1| (AJ000685) GTP cyclohydrolase [Streptococcus pyogenes]. | 0.971 |
folC | folK | SMU_967 | SMU_971 | Putative folyl-polyglutamate synthetase; Best Blastp Hit: sp|Q05865|FOLC_BACSU FOLYLPOLYGLUTAMATE SYNTHASE (FOLYLPOLY-GAMMA-GLUTAMATE SYNTHETASE) (FPGS) >gi|421496|pir||B40646 folyl-polyglutamate synthetase folC - Bacillus subtilis >gi|142936|gb|AAB59021.1| (L04520) folyl-polyglutamate synthetase [Bacillus subtilis] >gi|2635273|emb|CAB14768.1| (Z99118) folyl-polyglutamate synthetase [Bacillus subtilis]. | Putative 2-amino-4-hydroxy-6-hydroxymethylpteridine pyrophosphokinase; Best Blastp Hit: dbj|BAB03814.1| (AP001507) 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase [Bacillus halodurans]. | 0.986 |
folC | folP | SMU_967 | SMU_969 | Putative folyl-polyglutamate synthetase; Best Blastp Hit: sp|Q05865|FOLC_BACSU FOLYLPOLYGLUTAMATE SYNTHASE (FOLYLPOLY-GAMMA-GLUTAMATE SYNTHETASE) (FPGS) >gi|421496|pir||B40646 folyl-polyglutamate synthetase folC - Bacillus subtilis >gi|142936|gb|AAB59021.1| (L04520) folyl-polyglutamate synthetase [Bacillus subtilis] >gi|2635273|emb|CAB14768.1| (Z99118) folyl-polyglutamate synthetase [Bacillus subtilis]. | Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. | 0.995 |
folE | SMU_1046c | SMU_968 | SMU_1046c | Best Blastp Hit: sp|O33723|GCH1_STRPY GTP CYCLOHYDROLASE I (GTP-CH-I) >gi|3242315|emb|CAA04237.1| (AJ000685) GTP cyclohydrolase [Streptococcus pyogenes]. | Putative GTP pyrophosphokinase; Best Blastp Hit: dbj|BAB06568.1| (AP001516) GTP pyrophosphokinase [Bacillus halodurans]. | 0.800 |
folE | SMU_917c | SMU_968 | SMU_917c | Best Blastp Hit: sp|O33723|GCH1_STRPY GTP CYCLOHYDROLASE I (GTP-CH-I) >gi|3242315|emb|CAA04237.1| (AJ000685) GTP cyclohydrolase [Streptococcus pyogenes]. | Putative 6-pyruvoyl tetrahydropterin synthase; Best Blastp Hit: pir||C72425 hypothetical protein TM0038 - Thermotoga maritima (strain MSB8) >gi|4980523|gb|AAD35132.1|AE001691_6 (AE001691) 6-pyruvoyl tetrahydrobiopterin synthase, putative [Thermotoga maritima]. | 0.988 |
folE | asd | SMU_968 | SMU_989 | Best Blastp Hit: sp|O33723|GCH1_STRPY GTP CYCLOHYDROLASE I (GTP-CH-I) >gi|3242315|emb|CAA04237.1| (AJ000685) GTP cyclohydrolase [Streptococcus pyogenes]. | Aspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. | 0.830 |
folE | folA | SMU_968 | SMU_970 | Best Blastp Hit: sp|O33723|GCH1_STRPY GTP CYCLOHYDROLASE I (GTP-CH-I) >gi|3242315|emb|CAA04237.1| (AJ000685) GTP cyclohydrolase [Streptococcus pyogenes]. | Putative dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | 0.986 |
folE | folC | SMU_968 | SMU_967 | Best Blastp Hit: sp|O33723|GCH1_STRPY GTP CYCLOHYDROLASE I (GTP-CH-I) >gi|3242315|emb|CAA04237.1| (AJ000685) GTP cyclohydrolase [Streptococcus pyogenes]. | Putative folyl-polyglutamate synthetase; Best Blastp Hit: sp|Q05865|FOLC_BACSU FOLYLPOLYGLUTAMATE SYNTHASE (FOLYLPOLY-GAMMA-GLUTAMATE SYNTHETASE) (FPGS) >gi|421496|pir||B40646 folyl-polyglutamate synthetase folC - Bacillus subtilis >gi|142936|gb|AAB59021.1| (L04520) folyl-polyglutamate synthetase [Bacillus subtilis] >gi|2635273|emb|CAB14768.1| (Z99118) folyl-polyglutamate synthetase [Bacillus subtilis]. | 0.971 |