STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
asdAspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. (358 aa)    
Predicted Functional Partners:
akh
Putative aspartokinase; Best Blastp Hit: sp|P94417|AK3_BACSU PROBABLE ASPARTOKINASE (ASPARTATE KINASE) >gi|7474867|pir||A69763 homoserine dehydrogenase homolog yclM - Bacillus subtilis >gi|1805449|dbj|BAA09011.1| (D50453) homologue of aspartokinase 2 alpha and beta subunits LysC of B. subtilis [Bacillus subtilis] >gi|2632680|emb|CAB12187.1| (Z99106) similar to homoserine dehydrogenase [Bacillus subtilis]; Belongs to the aspartokinase family.
 
 
 0.999
dapA
Putative dihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
 
 
 0.991
SMU_965
Best Blastp Hit: sp|P52985|DHOM_LACLA HOMOSERINE DEHYDROGENASE (HDH) >gi|2117450|pir||JC6049 homoserine dehydrogenase (EC 1.1.1.3) - Lactococcus lactis >gi|1255939|emb|CAA65713.1| (X96988) hom [Lactococcus lactis].
  
 0.964
dapB
Putative dihydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
 
  
 0.952
dapH
Putative tetrahydrodipicolinate succinylase; Catalyzes the transfer of an acetyl group from acetyl-CoA to tetrahydrodipicolinate.
  
 0.875
folE
Best Blastp Hit: sp|O33723|GCH1_STRPY GTP CYCLOHYDROLASE I (GTP-CH-I) >gi|3242315|emb|CAA04237.1| (AJ000685) GTP cyclohydrolase [Streptococcus pyogenes].
  
  
 0.830
citZ
Citrate synthase; Best Blastp Hit: sp|Q59939|CISZ_STRMU CITRATE SYNTHASE >gi|1421813|gb|AAC44825.1| (U62799) citrate synthase [Streptococcus mutans].
   
 
 0.730
pgk
Phosphoglycerate kinase; Best Blastp Hit: sp|Q9Z5C4|PGK_STAAU PHOSPHOGLYCERATE KINASE >gi|4490614|emb|CAB38646.1| (AJ133520) phosphoglycerate kinase [Staphylococcus aureus]; Belongs to the phosphoglycerate kinase family.
  
 
 0.668
gltA
Best Blastp Hit: dbj|BAB05447.1| (AP001513) glutamate synthase (large subunit) [Bacillus halodurans].
  
  
 0.650
thrB
Homoserine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily.
 
  
 0.601
Your Current Organism:
Streptococcus mutans
NCBI taxonomy Id: 210007
Other names: S. mutans UA159, Streptococcus mutans UA159, Streptococcus mutans str. UA159
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