node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
SDM17764.1 | SDN08015.1 | SAMN04489726_0189 | SAMN04489726_4802 | AefR-like transcriptional repressor, C-terminal region. | DNA-binding transcriptional regulator, AcrR family. | 0.505 |
SDM20477.1 | SDN08015.1 | SAMN04489726_0347 | SAMN04489726_4802 | Proteasome accessory factor A. | DNA-binding transcriptional regulator, AcrR family. | 0.584 |
SDM20477.1 | arc | SAMN04489726_0347 | SAMN04489726_0338 | Proteasome accessory factor A. | Proteasome-associated ATPase; ATPase which is responsible for recognizing, binding, unfolding and translocation of pupylated proteins into the bacterial 20S proteasome core particle. May be essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C-termini of the proteasomal ATPase may function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis. | 0.925 |
SDM97183.1 | SDN08015.1 | SAMN04489726_4262 | SAMN04489726_4802 | Cobalamin-independent synthase, Catalytic domain; Manually curated. | DNA-binding transcriptional regulator, AcrR family. | 0.607 |
SDM97183.1 | SDN32734.1 | SAMN04489726_4262 | SAMN04489726_6071 | Cobalamin-independent synthase, Catalytic domain; Manually curated. | Anion-transporting ATPase, ArsA/GET3 family. | 0.426 |
SDN08004.1 | SDN08015.1 | SAMN04489726_4801 | SAMN04489726_4802 | Pimeloyl-ACP methyl ester carboxylesterase. | DNA-binding transcriptional regulator, AcrR family. | 0.541 |
SDN08015.1 | SDM17764.1 | SAMN04489726_4802 | SAMN04489726_0189 | DNA-binding transcriptional regulator, AcrR family. | AefR-like transcriptional repressor, C-terminal region. | 0.505 |
SDN08015.1 | SDM20477.1 | SAMN04489726_4802 | SAMN04489726_0347 | DNA-binding transcriptional regulator, AcrR family. | Proteasome accessory factor A. | 0.584 |
SDN08015.1 | SDM97183.1 | SAMN04489726_4802 | SAMN04489726_4262 | DNA-binding transcriptional regulator, AcrR family. | Cobalamin-independent synthase, Catalytic domain; Manually curated. | 0.607 |
SDN08015.1 | SDN08004.1 | SAMN04489726_4802 | SAMN04489726_4801 | DNA-binding transcriptional regulator, AcrR family. | Pimeloyl-ACP methyl ester carboxylesterase. | 0.541 |
SDN08015.1 | SDN32734.1 | SAMN04489726_4802 | SAMN04489726_6071 | DNA-binding transcriptional regulator, AcrR family. | Anion-transporting ATPase, ArsA/GET3 family. | 0.467 |
SDN08015.1 | arc | SAMN04489726_4802 | SAMN04489726_0338 | DNA-binding transcriptional regulator, AcrR family. | Proteasome-associated ATPase; ATPase which is responsible for recognizing, binding, unfolding and translocation of pupylated proteins into the bacterial 20S proteasome core particle. May be essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C-termini of the proteasomal ATPase may function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis. | 0.445 |
SDN08015.1 | pafA | SAMN04489726_4802 | SAMN04489726_0354 | DNA-binding transcriptional regulator, AcrR family. | Proteasome accessory factor A; Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side- chain amino group of a substrate lysine. | 0.571 |
SDN32734.1 | SDM97183.1 | SAMN04489726_6071 | SAMN04489726_4262 | Anion-transporting ATPase, ArsA/GET3 family. | Cobalamin-independent synthase, Catalytic domain; Manually curated. | 0.426 |
SDN32734.1 | SDN08015.1 | SAMN04489726_6071 | SAMN04489726_4802 | Anion-transporting ATPase, ArsA/GET3 family. | DNA-binding transcriptional regulator, AcrR family. | 0.467 |
arc | SDM20477.1 | SAMN04489726_0338 | SAMN04489726_0347 | Proteasome-associated ATPase; ATPase which is responsible for recognizing, binding, unfolding and translocation of pupylated proteins into the bacterial 20S proteasome core particle. May be essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C-termini of the proteasomal ATPase may function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis. | Proteasome accessory factor A. | 0.925 |
arc | SDN08015.1 | SAMN04489726_0338 | SAMN04489726_4802 | Proteasome-associated ATPase; ATPase which is responsible for recognizing, binding, unfolding and translocation of pupylated proteins into the bacterial 20S proteasome core particle. May be essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C-termini of the proteasomal ATPase may function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis. | DNA-binding transcriptional regulator, AcrR family. | 0.445 |
arc | pafA | SAMN04489726_0338 | SAMN04489726_0354 | Proteasome-associated ATPase; ATPase which is responsible for recognizing, binding, unfolding and translocation of pupylated proteins into the bacterial 20S proteasome core particle. May be essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C-termini of the proteasomal ATPase may function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis. | Proteasome accessory factor A; Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side- chain amino group of a substrate lysine. | 0.960 |
pafA | SDN08015.1 | SAMN04489726_0354 | SAMN04489726_4802 | Proteasome accessory factor A; Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side- chain amino group of a substrate lysine. | DNA-binding transcriptional regulator, AcrR family. | 0.571 |
pafA | arc | SAMN04489726_0354 | SAMN04489726_0338 | Proteasome accessory factor A; Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side- chain amino group of a substrate lysine. | Proteasome-associated ATPase; ATPase which is responsible for recognizing, binding, unfolding and translocation of pupylated proteins into the bacterial 20S proteasome core particle. May be essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C-termini of the proteasomal ATPase may function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis. | 0.960 |