node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
SO_1769 | aptA | SO_1769 | SO_3497 | Glutamate decarboxylase. | Beta-alanine-pyruvate transaminase AptA; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | 0.823 |
SO_1769 | panC | SO_1769 | SO_0869 | Glutamate decarboxylase. | Pantoate--beta-alanine ligase PanC; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family. | 0.946 |
SO_1769 | puuE | SO_1769 | SO_1276 | Glutamate decarboxylase. | GABA aminotransferase PLP-dependent PuuE; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | 0.950 |
aptA | SO_1769 | SO_3497 | SO_1769 | Beta-alanine-pyruvate transaminase AptA; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | Glutamate decarboxylase. | 0.823 |
aptA | panC | SO_3497 | SO_0869 | Beta-alanine-pyruvate transaminase AptA; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | Pantoate--beta-alanine ligase PanC; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family. | 0.916 |
aptA | puuE | SO_3497 | SO_1276 | Beta-alanine-pyruvate transaminase AptA; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | GABA aminotransferase PLP-dependent PuuE; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | 0.928 |
cmk | panC | SO_2403 | SO_0869 | Cytidylate kinase Cmk. | Pantoate--beta-alanine ligase PanC; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family. | 0.908 |
coaA | dfp | SO_0215 | SO_4249 | Pantothenate kinase CoaA. | Coenzyme A biosynthesis bifunctional protein CoaBC; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | 0.935 |
coaA | panC | SO_0215 | SO_0869 | Pantothenate kinase CoaA. | Pantoate--beta-alanine ligase PanC; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family. | 0.916 |
dfp | coaA | SO_4249 | SO_0215 | Coenzyme A biosynthesis bifunctional protein CoaBC; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | Pantothenate kinase CoaA. | 0.935 |
dfp | panB | SO_4249 | SO_0870 | Coenzyme A biosynthesis bifunctional protein CoaBC; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | 3-methyl-2-oxobutanoate hydroxymethyltransferase PanB; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family. | 0.580 |
dfp | panC | SO_4249 | SO_0869 | Coenzyme A biosynthesis bifunctional protein CoaBC; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | Pantoate--beta-alanine ligase PanC; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family. | 0.906 |
dfp | panE | SO_4249 | SO_3817 | Coenzyme A biosynthesis bifunctional protein CoaBC; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | 2-dehydropantoate 2-reductase PanE; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid. | 0.407 |
panB | dfp | SO_0870 | SO_4249 | 3-methyl-2-oxobutanoate hydroxymethyltransferase PanB; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family. | Coenzyme A biosynthesis bifunctional protein CoaBC; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | 0.580 |
panB | panC | SO_0870 | SO_0869 | 3-methyl-2-oxobutanoate hydroxymethyltransferase PanB; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family. | Pantoate--beta-alanine ligase PanC; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family. | 0.999 |
panB | panE | SO_0870 | SO_3817 | 3-methyl-2-oxobutanoate hydroxymethyltransferase PanB; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family. | 2-dehydropantoate 2-reductase PanE; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid. | 0.981 |
panB | trpD | SO_0870 | SO_3021 | 3-methyl-2-oxobutanoate hydroxymethyltransferase PanB; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family. | Anthranilate phosphoribosyltransferase TrpD; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA). | 0.810 |
panC | SO_1769 | SO_0869 | SO_1769 | Pantoate--beta-alanine ligase PanC; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family. | Glutamate decarboxylase. | 0.946 |
panC | aptA | SO_0869 | SO_3497 | Pantoate--beta-alanine ligase PanC; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family. | Beta-alanine-pyruvate transaminase AptA; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | 0.916 |
panC | cmk | SO_0869 | SO_2403 | Pantoate--beta-alanine ligase PanC; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family. | Cytidylate kinase Cmk. | 0.908 |