STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
gphPhosphoglycolate phosphatase; Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress. Belongs to the HAD-like hydrolase superfamily. CbbY/CbbZ/Gph/YieH family. (232 aa)    
Predicted Functional Partners:
ghrB
Putative D-isomer specific 2-hydroxyacid dehydrogenase; Catalyzes the NADPH-dependent reduction of glyoxylate and hydroxypyruvate into glycolate and glycerate, respectively. Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. GhrB subfamily.
 
  
  0.947
rpe
Similar to Escherichia coli ribulose-phosphate 3-epimerase Rpe SW:RPE_ECOLI (P32661) (225 aa) fasta scores: E(): 0, 88.6% id in 220 aa.
  
  
 0.918
trpS
tryptophanyl-tRNA synthetase; Catalyzes the attachment of tryptophan to tRNA(Trp). Belongs to the class-I aminoacyl-tRNA synthetase family.
  
  
 0.875
bisA
Molybdenum cofactor biosynthesis protein A; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate.
  
    0.828
nagE
Similar to Escherichia coli PTS system,N-acetylglucosamine-specific IIABC component NagE SW:PTAA_ECOLI (P09323) (648 aa) fasta scores: E(): 0, 52.6% id in 683 aa, and to Vibrio furnissii PTS permease for N-acetylglucosamine and glucose NagE TR:P96161 (EMBL:U65014) (496 aa) fasta scores: E(): 0, 69.9% id in 495 aa.
  
 
  0.739
hisB
Similar to Escherichia coli histidinol-phosphatase and imidazoleglycerol-phosphate dehydratase HisB TR:Q9S5G5 (P06987) (355 aa) fasta scores: E(): 0, 81.4% id in 355 aa,and to Salmonella typhimurium histidine biosynthesis bifunctional protein HisB [includes: histidinol-phosphatase HisB SW:HIS7_SALTY (P10368) (354 aa) fasta scores: E(): 0,78.9% id in 355 aa.
  
 
 0.707
YPO2407
Similar to Escherichia coli hypothetical protein YdiJ SW:YDIJ_ECOLI (P77748) (1018 aa) fasta scores: E(): 0,79.0% id in 1018 aa, and to Vibrio cholerae hypothetical protein VC1198 TR:Q9KSQ8 (EMBL:AE004199) (1021 aa) fasta scores: E(): 0, 62.1% id in 1018 aa.
  
 
 0.698
flgD
Putative basal-body rod modification protein; Required for flagellar hook formation. May act as a scaffolding protein.
   
   0.695
Fla
Basal-body rod modification protein FlgD; Required for flagellar hook formation. May act as a scaffolding protein.
    
   0.694
dniR
Similar to Escherichia coli membrane-bound lytic murein transglycosylase D precursor MltD SW:MLTD_ECOLI (P23931) (452 aa) fasta scores: E(): 0, 63.4% id in 470 aa.
  
   0.670
Your Current Organism:
Yersinia pestis
NCBI taxonomy Id: 214092
Other names: Y. pestis CO92, Yersinia pestis CO92, Yersinia pestis str. CO92, Yersinia pestis strain CO92
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.