STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
thiQThiamine transport ATP-binding protein; Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Thiamine importer (TC 3.A.1.19.1) family. (227 aa)    
Predicted Functional Partners:
thiP
Similar to Escherichia coli thiamine ABC transporter, permease protein ThiP SW:THIP_ECOLI (P31549) (536 aa) fasta scores: E(): 0, 74.0% id in 516 aa, and to Vibrio cholerae putative thiamine ABC transporter, permease protein VC2538 TR:Q9KP41 (EMBL:AE004323) (530 aa) fasta scores: E(): 0, 46.5% id in 512 aa.
 
 
 0.998
tbpA
Thiamine-binding periplasmic protein; Similar to Escherichia coli thiamine ABC transpoter,periplasmic binding protein protein TbpA SW:TBPA_ECOLI (P31550) (327 aa) fasta scores: E(): 0, 72.4% id in 323 aa,and to Vibrio cholerae thiamine ABC transporter,periplasmic thiamin-binding protein VC2539 TR:Q9KP40 (EMBL:AE004323) (330 aa) fasta scores: E(): 0, 68.0% id in 319 aa.
 
 
  0.989
thiK
Conserved hypothetical protein; Catalyzes the phosphorylation of thiamine to thiamine phosphate.
 
   
 0.645
sfuB
Similar to Serratia marcescens iron(III)-transport system permease SfuB SW:SFUB_SERMA (P21409) (527 aa) fasta scores: E(): 0, 78.8% id in 533 aa, and to Yersinia enterocolitica iron transport system protein YfuB TR:Q56926 (EMBL:Z47200) (528 aa) fasta scores: E(): 0, 87.1% id in 528 aa.
 
 
 0.637
YPO3049
Putative binding protein-dependent transport system, inner-membrane component; Similar to Streptomyces coelicolor putative membrane protein sc10a5.29C TR:O54120 (EMBL:AL021529) (589 aa) fasta scores: E(): 0, 30.8% id in 574 aa.
  
 
 0.633
thiE
Thiamine-phosphate pyrophosphorylase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family.
   
  
 0.628
panF
Similar to Escherichia coli sodium/pantothenate symporter PanF SW:PANF_ECOLI (P16256) (483 aa) fasta scores: E(): 0, 82.8% id in 470 aa, and to Haemophilus influenzae sodium/pantothenate symporter PanF or Hi0975 SW:PANF_HAEIN (P44963) (484 aa) fasta scores: E(): 0, 63.1% id in 472 aa; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
   
  
 0.586
rpsK
30S ribosomal protein S11; Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine- Dalgarno cleft in the 70S ribosome; Belongs to the universal ribosomal protein uS11 family.
  
     0.546
b0051
Dimethyladenosine transferase; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.
  
    0.544
bioF
8-amino-7-oxononanoate synthase; Catalyzes the decarboxylative condensation of pimeloyl-[acyl- carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide.
      
 0.530
Your Current Organism:
Yersinia pestis
NCBI taxonomy Id: 214092
Other names: Y. pestis CO92, Yersinia pestis CO92, Yersinia pestis str. CO92, Yersinia pestis strain CO92
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