STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
speABiosynthetic arginine decarboxylase; Catalyzes the biosynthesis of agmatine from arginine. (659 aa)    
Predicted Functional Partners:
aguA
Similar to Pseudomonas aeruginosa conserved hypothetical protein PA0292 TR:AAG03681 (EMBL:AE004467) (368 aa) fasta scores: E(): 0, 57.5% id in 358 aa, and to eukaryotic Arabidopsis thaliana hypothetical protein T22D6_110 TR:Q9LEZ0 (EMBL:AL357612) (383 aa) fasta scores: E(): 0, 51.4% id in 368 aa.
 
  
 0.984
argH
Similar to Escherichia coli argininosuccinate lyase ArgH SW:ARLY_ECOLI (P11447) (457 aa) fasta scores: E(): 0,89.0% id in 456 aa, and to Vibrio cholerae argininosuccinate lyase VC2641 TR:Q9KNT9 (EMBL:AE004330) (458 aa) fasta scores: E(): 0, 74.3% id in 456 aa.
     
 0.945
fsrB
Flavohemoprotein; Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress; Belongs to the globin family. Two-domain flavohemoproteins subfamily.
   
 
  0.532
YPO1201
Putative amino acid decarboxylase; Similar to Escherichia coli biodegradative arginine decarboxylase AdiA or Adi SW:ADIA_ECOLI (P28629) (755 aa) fasta scores: E(): 0, 52.4% id in 757 aa, and to Vibrio cholerae ornithine decarboxylase, inducible VCA1063 TR:Q9KKN9 (EMBL:AE004431) (720 aa) fasta scores: E(): 0,34.0% id in 633 aa.
     
 0.506
YPO0938
Putative carbon-nitrogen hydrolase; Similar to Pseudomonas aeruginosa probable hydratase PA0293 TR:AAG03682 (EMBL:AE004467) (292 aa) fasta scores: E(): 0, 63.9% id in 291 aa, and to eukaryoyic Lycopersicon esculentum (Tomato) beta-alanine synthase TR:Q9XGI9 (EMBL:Y19104) (300 aa) fasta scores: E(): 0, 60.1% id in 288 aa.
 
   
 0.505
fabD
Similar to Escherichia coli malonyl CoA-acyl carrier protein transacylase FabD or TfpA SW:FABD_ECOLI (P25715) (308 aa) fasta scores: E(): 0, 78.5% id in 307 aa, and to Salmonella typhimurium malonyl CoA-acyl carrier protein transacylase SW:FABD_SALTY (O85140) (308 aa) fasta scores: E(): 0, 79.7% id in 306 aa.
   
    0.485
metK
S-adenosylmethionine synthetase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
  
  
 0.478
YPO0928
Putative Rieske protein; Similar to Pseudomonas putida benzene 1,2-dioxygenase system ferredoxin component BedB SW:BEDB_PSEPU (Q07947) (107 aa) fasta scores: E(): 6.6e-12,35.8% id in 106 aa, and to Acinetobacter sp ADP1 hypothetical protein TR:O24846 (EMBL:AF009672) (101 aa) fasta scores: E(): 1.9e-19, 42.6% id in 101 aa.
       0.470
lysA
Diaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine.
  
  
 0.466
YPO1463
Putative acyl transferase; Similar to Bacillus subtilis malonyl CoA-acyl carrier protein transacylase FabD SW:FABD_BACSU (P71019) (317 aa) fasta scores: E(): 4.5e-28, 36.2% id in 290 aa,and to Bacillus subtilis putative polyketide synthesis protein PksC TR:O34825 (EMBL:Z99112) (288 aa) fasta scores: E(): 0, 45.1% id in 275 aa.
   
    0.435
Your Current Organism:
Yersinia pestis
NCBI taxonomy Id: 214092
Other names: Y. pestis CO92, Yersinia pestis CO92, Yersinia pestis str. CO92, Yersinia pestis strain CO92
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