STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
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Gene Fusion
Cooccurrence
Coexpression
Experiments
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[Homology]
Score
bisAMolybdenum cofactor biosynthesis protein A; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate. (326 aa)    
Predicted Functional Partners:
chlA3
Molybdenum cofactor biosynthesis protein C; Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP); Belongs to the MoaC family.
 
 0.999
chlA5
Molybdopterin [mpt] converting factor, subunit 2; Converts molybdopterin precursor Z into molybdopterin. This requires the incorporation of two sulfur atoms into precursor Z to generate a dithiolene group. The sulfur is provided by MoaD (By similarity); Belongs to the MoaE family.
 
 
 0.979
chlA4
Similar to Escherichia coli molybdopterin [mpt] converting factor, subunit 1 MoaD SW:MOAD_ECOLI (P30748) (81 aa) fasta scores: E(): 2.9e-23, 71.6% id in 81 aa, and to Vibrio cholerae molybdenum cofactor biosynthesis protein D vc1027 TR:Q9KT78 (EMBL:AE004184) (81 aa) fasta scores: E(): 2.4e-17, 63.0% id in 81 aa.
 
 
 0.969
folE
Similar to Escherichia coli GTP cyclohydrolase I SW:GCH1_ECOLI (P27511) (221 aa) fasta scores: E(): 0, 90.0% id in 219 aa, and to Vibrio cholerae GTP cyclohydrolase Vca0616 TR:Q9KLX5 (EMBL:AE004391) (230 aa) fasta scores: E(): 0, 70.2% id in 218 aa.
    
  0.940
ribA
GTP cyclohydrolase II; Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.
   
 
  0.933
bisB
Molybdopterin biosynthesis protein; Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP. Belongs to the MoeA family.
 
 0.931
chlG
Similar to Escherichia coli molybdopterin biosynthesis protein Mog SW:MOG_ECOLI (P28694) (195 aa) fasta scores: E(): 0, 87.2% id in 195 aa, and to Haemophilus influenzae molybdopterin biosynthesis protein Mog SW:MOG_HAEIN (P44645) (197 aa) fasta scores: E(): 0,75.4% id in 187 aa.
 
 
 0.924
barA
Two-component regulatory protein; Similar to Escherichia coli sensor protein BarA SW:BARA_ECOLI (P26607) (918 aa) fasta scores: E(): 0, 61.6% id in 928 aa, and to Erwinia carotovora subsp. carotovora sensor/regulator protein RpfA TR:O08235 (EMBL:U62023) (929 aa) fasta scores: E(): 0, 59.7% id in 938 aa.
  
 0.839
gph
Phosphoglycolate phosphatase; Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress. Belongs to the HAD-like hydrolase superfamily. CbbY/CbbZ/Gph/YieH family.
  
    0.828
nrdD
Similar to Escherichia coli anaerobic ribonucleoside-triphosphate reductase NrdD SW:NRDD_ECOLI (P28903) (712 aa) fasta scores: E(): 0, 86.0% id in 709 aa,and to Salmonella typhimurium anaerobic ribonucleoside-triphosphate reductase NrdD TR:Q9L646 (EMBL:AF242390) (712 aa) fasta scores: E(): 0, 87.2% id in 709 aa.
   
 
 0.820
Your Current Organism:
Yersinia pestis
NCBI taxonomy Id: 214092
Other names: Y. pestis CO92, Yersinia pestis CO92, Yersinia pestis str. CO92, Yersinia pestis strain CO92
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