STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
YPO1288Putative D-isomer specific 2-hydroxyacid dehydrogenase family protein; Similar to Streptomyces coelicolor putative dehydrogenase SCE65.14C TR:Q9RKF9 (EMBL:AL133236) (344 aa) fasta scores: E(): 0, 35.7% id in 297 aa, and to Bacillus subtilis D-3-phosphoglycerate dehydrogenase SerA SW:SERA_BACSU (P35136) (525 aa) fasta scores: E(): 5.7e-31,36.1% id in 291 aa; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (321 aa)    
Predicted Functional Partners:
serC
Phosphoserine aminotransferase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.
  
 0.920
YPO1289
Similar to Streptomyces coelicolor hypothetical protein SCF41.20c TR:Q9RJU9 (EMBL:AL117387) (390 aa) fasta scores: E(): 0, 54.7% id in 380 aa.
  
    0.833
nifJ
Similar to Escherichia coli probable pyruvate-flavodoxin oxidoreductase YdbK SW:NIFJ_ECOLI (P52647) (1174 aa) fasta scores: E(): 0, 80.5% id in 1177 aa, and to Klebsiella pneumoniae pyruvate-flavodoxin oxidoreductase NifJ SW:NIFJ_KLEPN (P03833) (1171 aa) fasta scores: E(): 0, 48.0% id in 1184 aa.
  
 
 0.833
YPO1287
Putative short chain oxidoreductase; Similar to Gluconobacter oxydans gluconate 5-dehydrogenase Gno SW:GNO_GLUOX (P50199) (256 aa) fasta scores: E(): 9e-27, 37.5% id in 256 aa, and to Thermotoga maritima oxidoreductase, short chain dehydrogenase/reductase family TM0297 TR:Q9WYD3 (EMBL:AE001711) (257 aa) fasta scores: E(): 5.4e-32, 48.4% id in 248 aa.
    0.813
metL
Cystathionine gamma-synthase (pseudogene); PS00868 Cys/Met metabolism enzymes pyridoxal-phosphate attachment site; In the C-terminal section; belongs to the homoserine dehydrogenase family.
  
 0.790
thrA
Similar to Escherichia coli bifunctional aspartokinase/homoserine dehydrogenase I ThrA SW:AK1H_ECOLI (P00561) (820 aa) fasta scores: E(): 0, 82.0% id in 821 aa,and to Serratia marcescens bifunctional aspartokinase/homoserine dehydrogenase I ThrA SW:AK1H_SERMA (P27725) (819 aa) fasta scores: E(): 0, 89.9% id in 819 aa; In the C-terminal section; belongs to the homoserine dehydrogenase family.
  
 0.790
b2066
Uridine kinase; Similar to Escherichia coli uridine kinase SW:URK_ECOLI (P31218) (213 aa) fasta scores: E(): 0, 91.1% id in 213 aa, and to Vibrio cholerae uridine kinase vc1038 TR:Q9KT67 (EMBL:AE004185) (219 aa) fasta scores: E(): 0,75.0% id in 208 aa.
   
  0.777
rplP
50S ribosomal protein L16; Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs; Belongs to the universal ribosomal protein uL16 family.
   
   0.737
rplF
50S ribosomal protein L6; This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center; Belongs to the universal ribosomal protein uL6 family.
    
   0.729
rpmA
Similar to Escherichia coli 50S ribosomal protein L27 RpmA SW:RL27_ECOLI (P02427) (84 aa) fasta scores: E(): 5e-31, 94.0% id in 84 aa, and to Vibrio cholerae ribosomal protein L27 Vc0436 TR:Q9KUS9 (EMBL:AE004131) (86 aa) fasta scores: E(): 1.2e-29, 91.6% id in 83 aa; Belongs to the bacterial ribosomal protein bL27 family.
   
   0.723
Your Current Organism:
Yersinia pestis
NCBI taxonomy Id: 214092
Other names: Y. pestis CO92, Yersinia pestis CO92, Yersinia pestis str. CO92, Yersinia pestis strain CO92
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