STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
rlmLConserved hypothetical protein; Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA. Belongs to the methyltransferase superfamily. RlmKL family. (706 aa)    
Predicted Functional Partners:
uup
Similar to Escherichia coli ABC transporter ATP-binding protein Uup SW:UUP_ECOLI (P43672) (635 aa) fasta scores: E(): 0, 77.4% id in 637 aa, and to Haemophilus influenzae ABC transporter ATP-binding protein Uup-1 SW:UUP1_HAEIN (Q57242) (647 aa) fasta scores: E(): 0,66.3% id in 641 aa.
 
  
 0.909
rth
Undecaprenyl pyrophosphate synthetase; Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with (2E,6E)-farnesyl diphosphate (E,E-FPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30Z,34E,38E)-undecaprenyl diphosphate (di- trans,octa-cis-UPP). UPP is the precursor of glycosyl carrier lipid in the biosynthesis of bacterial cell wall polysaccharide components such as peptidoglycan and lipopolysaccharide.
   
    0.814
pnp
Polyribonucleotide nucleotidyltransferase; Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'- direction.
  
    0.794
bipA
Putative GTPase; Similar to Salmonella typhimurium GTPase BipA TR:CAC14270 (EMBL:AJ276889) (607 aa) fasta scores: E(): 0,89.1% id in 606 aa and to Escherichia coli GTP-binding protein BipA which has shown to be important for virulence of EPEC strains. SW:TYPA_ECOLI (P32132) (591 aa) fasta scores: E(): 0, 89.3% id in 591 aa.
 
   0.784
rsuA
Ribosomal small subunit pseudouridine synthase A; Responsible for synthesis of pseudouridine from uracil-516 in 16S ribosomal RNA.
  
 
 0.779
rluB
Putative RNA pseudouridylate synthase-family protein; Responsible for synthesis of pseudouridine from uracil-2605 in 23S ribosomal RNA; Belongs to the pseudouridine synthase RsuA family.
  
 
 0.778
ymfC
Putative pseudouridine synthase; Responsible for synthesis of pseudouridine from uracil-2457 in 23S ribosomal RNA; Belongs to the pseudouridine synthase RsuA family.
  
 
 0.775
gltX
glutamyl-tRNA synthetase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
  
  
 0.739
ribD
Diaminohydroxyphosphoribosylaminopyrimidine deaminase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family.
  
  
 0.718
YPO2825
Similar to Escherichia coli hypothetical protein YbcJ SW:YBCJ_ECOLI (P45571) (70 aa) fasta scores: E(): 5.9e-18, 71.4% id in 70 aa, and to Neisseria meningitidis hypothetical protein NMA0633 TR:Q9JVX7 (EMBL:AL162753) (77 aa) fasta scores: E(): 1.1e-08, 46.9% id in 64 aa.
   
   0.712
Your Current Organism:
Yersinia pestis
NCBI taxonomy Id: 214092
Other names: Y. pestis CO92, Yersinia pestis CO92, Yersinia pestis str. CO92, Yersinia pestis strain CO92
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.