STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
cddCytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis. (294 aa)    
Predicted Functional Partners:
udp
Uridine phosphorylase; Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis. Belongs to the PNP/UDP phosphorylase family.
 
 
 0.997
b2066
Uridine kinase; Similar to Escherichia coli uridine kinase SW:URK_ECOLI (P31218) (213 aa) fasta scores: E(): 0, 91.1% id in 213 aa, and to Vibrio cholerae uridine kinase vc1038 TR:Q9KT67 (EMBL:AE004185) (219 aa) fasta scores: E(): 0,75.0% id in 208 aa.
  
 
 0.976
tdk
Thymidine kinase; Similar to Escherichia coli thymidine kinase Tdk SW:KITH_ECOLI (P23331) (205 aa) fasta scores: E(): 0, 76.4% id in 191 aa, and to Vibrio cholerae thymidine kinase VC1167 TR:Q9KST9 (EMBL:AE004197) (192 aa) fasta scores: E(): 0, 72.6% id in 190 aa.
  
 
 0.975
b4384
Similar to Escherichia coli purine nucleoside phosphorylase DeoD SW:DEOD_ECOLI (P09743) (238 aa) fasta scores: E(): 0, 91.1% id in 236 aa, and to Klebsiella pneumoniae purine nucleoside phosphorylase DeoD SW:DEOD_KLEPN (Q59482) (239 aa) fasta scores: E(): 0, 88.7% id in 238 aa.
  
 
 0.955
surE
Stationary-phase survival protein; Nucleotidase with a broad substrate specificity as it can dephosphorylate various ribo- and deoxyribonucleoside 5'-monophosphates and ribonucleoside 3'-monophosphates with highest affinity to 3'-AMP. Also hydrolyzes polyphosphate (exopolyphosphatase activity) with the preference for short-chain-length substrates (P20-25). Might be involved in the regulation of dNTP and NTP pools, and in the turnover of 3'-mononucleotides produced by numerous intracellular RNases (T1, T2, and F) during the degradation of various RNAs.
  
  
 0.951
cpdB
Similar to Escherichia coli 2',3'-cyclic-nucleotide 2'-phosphodiesterase precursor CpdB SW:CN16_ECOLI (P08331) (647 aa) fasta scores: E(): 0, 76.0% id in 646 aa, and to Yersinia enterocolitica 2',3'-cyclic-nucleotide 2'-phosphodiesterase precursor CpdB SW:CN16_YEREN (P53052) (652 aa) fasta scores: E(): 0, 91.3% id in 652 aa; Belongs to the 5'-nucleotidase family.
  
 
 0.943
YPO2559
Conserved hypothetical protein; Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates.
     
 0.932
era
Putative GTP-binding protein; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
  
    0.863
deoC
Deoxyribose-phosphate aldolase; Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5- phosphate; Belongs to the DeoC/FbaB aldolase family. DeoC type 2 subfamily.
  
 
 0.713
deoC-2
Putative deoxyribose-phosphate aldolase; Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5- phosphate; Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.
  
 
 0.688
Your Current Organism:
Yersinia pestis
NCBI taxonomy Id: 214092
Other names: Y. pestis CO92, Yersinia pestis CO92, Yersinia pestis str. CO92, Yersinia pestis strain CO92
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