STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
argGSimilar to Escherichia coli argininosuccinate synthase ArgG SW:ASSY_ECOLI (P22767) (446 aa) fasta scores: E(): 0, 90.5% id in 440 aa, and to Neisseria meningitidis argininosuccinate synthase ArgG or Nma0303 TR:Q9JWM1 (EMBL:AL162752) (447 aa) fasta scores: E(): 0, 80.7% id in 440 aa; Belongs to the argininosuccinate synthase family. Type 2 subfamily. (455 aa)    
Predicted Functional Partners:
argH
Similar to Escherichia coli argininosuccinate lyase ArgH SW:ARLY_ECOLI (P11447) (457 aa) fasta scores: E(): 0,89.0% id in 456 aa, and to Vibrio cholerae argininosuccinate lyase VC2641 TR:Q9KNT9 (EMBL:AE004330) (458 aa) fasta scores: E(): 0, 74.3% id in 456 aa.
 
 
 0.998
argI
Ornithine carbamoyltransferase chain I; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
  
 
 0.997
b0033
Similar to Escherichia coli carbamoyl-phosphate synthase large chain CarB SW:CARB_ECOLI (P00968) (1072 aa) fasta scores: E(): 0, 92.6% id in 1072 aa, and to Salmonella typhimurium carbamoyl-phosphate synthase large chain CarB SW:CARB_SALTY (P14846) (1074 aa) fasta scores: E(): 0, 92.7% id in 1072 aa.
 
 
 0.995
argE
Similar to Escherichia coli acetylornithine deacetylase ArgE SW:ARGE_ECOLI (P23908) (383 aa) fasta scores: E(): 0, 77.5% id in 386 aa, and to Moritella sp 2674 acetylornithinase ArgE TR:Q9K4Z7 (EMBL:AJ252020) (381 aa) fasta scores: E(): 0, 58.4% id in 385 aa; Belongs to the peptidase M20A family. ArgE subfamily.
 
 0.993
b0032
Similar to Escherichia coli carbamoyl-phosphate synthase small chain CarA SW:CARA_ECOLI (P00907) (382 aa) fasta scores: E(): 0, 86.4% id in 381 aa, and to Salmonella typhimurium carbamoyl-phosphate synthase small chain CarA SW:CARA_SALTY (P14845) (382 aa) fasta scores: E(): 0, 86.4% id in 381 aa; Belongs to the CarA family.
  
 
 0.979
metL
Cystathionine gamma-synthase (pseudogene); PS00868 Cys/Met metabolism enzymes pyridoxal-phosphate attachment site; In the C-terminal section; belongs to the homoserine dehydrogenase family.
  
 
 0.973
thrA
Similar to Escherichia coli bifunctional aspartokinase/homoserine dehydrogenase I ThrA SW:AK1H_ECOLI (P00561) (820 aa) fasta scores: E(): 0, 82.0% id in 821 aa,and to Serratia marcescens bifunctional aspartokinase/homoserine dehydrogenase I ThrA SW:AK1H_SERMA (P27725) (819 aa) fasta scores: E(): 0, 89.9% id in 819 aa; In the C-terminal section; belongs to the homoserine dehydrogenase family.
  
 
 0.973
argA
Similar to Escherichia coli amino-acid acetyltransferase ArgA SW:ARGA_ECOLI (P08205) (443 aa) fasta scores: E(): 0, 87.3% id in 441 aa, and to Vibrio cholerae N-acetylglutamate synthase VC2316 TR:Q9KPQ0 (EMBL:AE004301) (456 aa) fasta scores: E(): 0, 65.8% id in 445 aa; Belongs to the acetyltransferase family. ArgA subfamily.
 
 
 0.972
argC
N-acetyl-gamma-glutamyl-phosphate reductase; Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde. Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
  
  
 0.959
adeK
Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family.
  
 
 0.957
Your Current Organism:
Yersinia pestis
NCBI taxonomy Id: 214092
Other names: Y. pestis CO92, Yersinia pestis CO92, Yersinia pestis str. CO92, Yersinia pestis strain CO92
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