STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pagPPutative exported protein; Transfers a palmitate residue from the sn-1 position of a phospholipid to the N-linked hydroxymyristate on the proximal unit of lipid A or its precursors. (199 aa)    
Predicted Functional Partners:
arnT
Dolichyl-phosphate-mannose-protein mannosyltransferase-family protein; Catalyzes the transfer of the L-Ara4N moiety of the glycolipid undecaprenyl phosphate-alpha-L-Ara4N to lipid A. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides. Belongs to the glycosyltransferase 83 family.
  
  
 0.979
lpxT
Putative membrane protein; Involved in the modification of the lipid A domain of lipopolysaccharides (LPS). Transfers a phosphate group from undecaprenyl pyrophosphate (C55-PP) to lipid A to form lipid A 1- diphosphate. Contributes to the recycling of undecaprenyl phosphate (C55-P); Belongs to the LpxT phosphotransferase family.
  
 
 0.973
msbB
Lipid A biosynthesis acyltransferase; Catalyzes the transfer of myristate from myristoyl-acyl carrier protein (ACP) to Kdo(2)-(lauroyl)-lipid IV(A) to form Kdo(2)- lipid A.
     
 0.972
lpxK
Tetraacyldisaccharide 4'-kinase; Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA).
   
 
 0.953
YPO2377
Putative membrane protein; Similar to Escherichia coli hypothetical protein YjdB SW:YJDB_ECOLI (P30845) (547 aa) fasta scores: E(): 0,51.0% id in 533 aa, and to Salmonella typhimurium hypothetical protein YjdB SW:YJDB_SALTY (P36555) (547 aa) fasta scores: E(): 0, 49.9% id in 529 aa.
   
 
 0.951
yhjW
Similar to Escherichia coli membrane-protein YhjW SW:YHJW_ECOLI (P37661) (574 aa) fasta scores: E(): 0, 63.4% id in 555 aa, and to Pseudomonas aeruginosa hypothetical protein PAa3310 TR:AAG06698 (EMBL:AE004753) (551 aa) fasta scores: E(): 1.5e-27, 27.6% id in 572 aa.
  
 
 0.943
kdtA
3-deoxy-D-manno-octulosonic-acid transferase; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family.
     
 0.937
phoP
Response regulator protein; Similar to the previously sequenced Yersinia pestis PhoP protein TR:P74992 (EMBL:Y08758) (223 aa) fasta scores: E(): 0, 100.0% id in 223 aa, to Yersinia pseudotuberculosis PhoP protein TR:P74991 (EMBL:X66587) (223 aa) fasta scores: E(): 0, 99.1% id in 223 aa, to Yersinia enterocolitica PhoP protein TR:O87919 (EMBL:AJ011832) (200 aa) fasta scores: E(): 0, 98.5% id in 200 aa, and to Escherichia coli transcriptional regulatory protein PhoP SW:PHOP_ECOLI (P23836) (223 aa) fasta scores: E(): 0, 81.1% id in 222 aa.
   
  
 0.689
YPO0142
Putative membrane protein; Similar to Escherichia coli hypothetical 79.5 kDa protein in mrcA-pckA intergenic region YrfF SW:YRFF_ECOLI (P45800) (711 aa) fasta scores: E(): 0, 53.6% id in 715 aa and to Proteus mirabilis UmoB TR:O86988 (EMBL:U66822) (702 aa) fasta scores: E(): 0, 43.4% id in 719 aa.
  
     0.680
phoQ
Sensor protein kinase; Similar to Escherichia coli membrane bound two component sensor protein PhoQ SW:PHOQ_ECOLI (P23837) (486 aa) fasta scores: E(): 0, 62.1% id in 478 aa, and to Salmonella typhimurium PhoQ protein TR:Q9L3L1 (EMBL:AJ272210) (487 aa) fasta scores: E(): 0, 62.4% id in 473 aa.
      
 0.651
Your Current Organism:
Yersinia pestis
NCBI taxonomy Id: 214092
Other names: Y. pestis CO92, Yersinia pestis CO92, Yersinia pestis str. CO92, Yersinia pestis strain CO92
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