STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
efeBConserved hypothetical protein; Involved in the recovery of exogenous heme iron. Extracts iron from heme while preserving the tetrapyrrol ring intact (By similarity). (434 aa)    
Predicted Functional Partners:
efeO
Putative exported protein; Involved in Fe(2+) uptake. Could be an iron-binding and/or electron-transfer component (By similarity).
 
  
 0.999
efeU
Putative membrane protein; Uptake of Fe(2+) ions across the membrane.
 
  
 0.991
YPO1941
Putative membrane protein; Previously sequenced as Yersinia pestis hypothetical protein TR:Q9ZC51 (EMBL:AL031866) (639 aa) fasta scores: E(): 0, 100.0% id in 639 aa. Similar to Campylobacter jejuni putative integral membrane protein Cj1658 TR:Q9PM19 (EMBL:AL139079) (696 aa) fasta scores: E(): 0, 31.9% id in 706 aa.
 
  
 0.850
YPO1784
Similar to Escherichia coli copper resistance protein C precursor PcoC SW:COPC_ECOLI (Q47454) (126 aa) fasta scores: E(): 4.7e-09, 36.6% id in 123 aa, and to Escherichia coli hypothetical 13.4 kDa protein in pphA-holE intergenic region precursor protein YobA SW:YOBA_ECOLI (P76279) (124 aa) fasta scores: E(): 2.8e-21, 50.8% id in 122 aa.
 
  
 0.762
pdxH
Pyridoxamine 5'-phosphate oxidase; Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).
      
 0.629
nifJ
Similar to Escherichia coli probable pyruvate-flavodoxin oxidoreductase YdbK SW:NIFJ_ECOLI (P52647) (1174 aa) fasta scores: E(): 0, 80.5% id in 1177 aa, and to Klebsiella pneumoniae pyruvate-flavodoxin oxidoreductase NifJ SW:NIFJ_KLEPN (P03833) (1171 aa) fasta scores: E(): 0, 48.0% id in 1184 aa.
     
 0.564
hmuS
Hemin transport protein; Part of the binding-protein-dependent transport system for hemin.
   
  
 0.541
feoA
Similar to Escherichia coli ferrous iron transport protein A, the function of which is not known, FeoA SW:FEOA_ECOLI (P33649) (75 aa) fasta scores: E(): 5.8e-19,77.5% id in 71 aa.
      
 0.485
feoC
Conserved hypothetical protein; May function as a transcriptional regulator that controls feoABC expression.
      
 0.478
feoB
Ferrous iron transport protein B; Probable transporter of a GTP-driven Fe(2+) uptake system. Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. FeoB GTPase (TC 9.A.8) family.
   
  
 0.430
Your Current Organism:
Yersinia pestis
NCBI taxonomy Id: 214092
Other names: Y. pestis CO92, Yersinia pestis CO92, Yersinia pestis str. CO92, Yersinia pestis strain CO92
Server load: low (40%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.