node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
YPO4065 | rluB | YPO4065 | YPO2213 | Similar to Escherichia coli hypothetical protein YibL SW:YIBL_ECOLI (P36564) (120 aa) fasta scores: E(): 2.9e-21, 61.2% id in 116 aa, and to the C-terminus of Vibrio cholerae hypothetical protein VCA0010 TR:Q9KNF4 (EMBL:AE004344) (145 aa) fasta scores: E(): 5.7e-10, 33.1% id in 118 aa. | Putative RNA pseudouridylate synthase-family protein; Responsible for synthesis of pseudouridine from uracil-2605 in 23S ribosomal RNA; Belongs to the pseudouridine synthase RsuA family. | 0.538 |
YPO4065 | rluC | YPO4065 | YPO1591 | Similar to Escherichia coli hypothetical protein YibL SW:YIBL_ECOLI (P36564) (120 aa) fasta scores: E(): 2.9e-21, 61.2% id in 116 aa, and to the C-terminus of Vibrio cholerae hypothetical protein VCA0010 TR:Q9KNF4 (EMBL:AE004344) (145 aa) fasta scores: E(): 5.7e-10, 33.1% id in 118 aa. | Ribosomal large subunit pseudouridine synthase C; Responsible for synthesis of pseudouridine from uracil at positions 955, 2504 and 2580 in 23S ribosomal RNA; Belongs to the pseudouridine synthase RluA family. | 0.522 |
cmk | engA | YPO1391 | YPO2875 | Cytidylate kinase; Similar to Escherichia coli cytidylate kinase Cmk SW:KCY_ECOLI (P23863) (227 aa) fasta scores: E(): 0, 84.5% id in 226 aa, and to Vibrio cholerae cytidylate kinase VC1916 TR:Q9KQT2 (EMBL:AE004267) (229 aa) fasta scores: E(): 0, 67.0% id in 224 aa. | Putative GTP-binding protein; GTPase that plays an essential role in the late steps of ribosome biogenesis; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family. | 0.993 |
cmk | rluB | YPO1391 | YPO2213 | Cytidylate kinase; Similar to Escherichia coli cytidylate kinase Cmk SW:KCY_ECOLI (P23863) (227 aa) fasta scores: E(): 0, 84.5% id in 226 aa, and to Vibrio cholerae cytidylate kinase VC1916 TR:Q9KQT2 (EMBL:AE004267) (229 aa) fasta scores: E(): 0, 67.0% id in 224 aa. | Putative RNA pseudouridylate synthase-family protein; Responsible for synthesis of pseudouridine from uracil-2605 in 23S ribosomal RNA; Belongs to the pseudouridine synthase RsuA family. | 0.862 |
engA | cmk | YPO2875 | YPO1391 | Putative GTP-binding protein; GTPase that plays an essential role in the late steps of ribosome biogenesis; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family. | Cytidylate kinase; Similar to Escherichia coli cytidylate kinase Cmk SW:KCY_ECOLI (P23863) (227 aa) fasta scores: E(): 0, 84.5% id in 226 aa, and to Vibrio cholerae cytidylate kinase VC1916 TR:Q9KQT2 (EMBL:AE004267) (229 aa) fasta scores: E(): 0, 67.0% id in 224 aa. | 0.993 |
engA | rlmL | YPO2875 | YPO1418 | Putative GTP-binding protein; GTPase that plays an essential role in the late steps of ribosome biogenesis; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family. | Conserved hypothetical protein; Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA. Belongs to the methyltransferase superfamily. RlmKL family. | 0.486 |
engA | rlmN | YPO2875 | YPO2882 | Putative GTP-binding protein; GTPase that plays an essential role in the late steps of ribosome biogenesis; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family. | Conserved hypothetical protein; Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs. m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity; Belongs to the radical SAM superfamily. RlmN family. | 0.577 |
engA | rluB | YPO2875 | YPO2213 | Putative GTP-binding protein; GTPase that plays an essential role in the late steps of ribosome biogenesis; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family. | Putative RNA pseudouridylate synthase-family protein; Responsible for synthesis of pseudouridine from uracil-2605 in 23S ribosomal RNA; Belongs to the pseudouridine synthase RsuA family. | 0.908 |
rbaB | rlmL | YPO2708 | YPO1418 | ATP-dependent RNA helicase; DEAD-box RNA helicase involved in the assembly of the 50S ribosomal subunit at low temperature. Exhibits RNA-stimulated ATP hydrolysis and RNA unwinding activity; Belongs to the DEAD box helicase family. SrmB subfamily. | Conserved hypothetical protein; Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA. Belongs to the methyltransferase superfamily. RlmKL family. | 0.576 |
rbaB | rlmN | YPO2708 | YPO2882 | ATP-dependent RNA helicase; DEAD-box RNA helicase involved in the assembly of the 50S ribosomal subunit at low temperature. Exhibits RNA-stimulated ATP hydrolysis and RNA unwinding activity; Belongs to the DEAD box helicase family. SrmB subfamily. | Conserved hypothetical protein; Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs. m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity; Belongs to the radical SAM superfamily. RlmN family. | 0.433 |
rbaB | rluB | YPO2708 | YPO2213 | ATP-dependent RNA helicase; DEAD-box RNA helicase involved in the assembly of the 50S ribosomal subunit at low temperature. Exhibits RNA-stimulated ATP hydrolysis and RNA unwinding activity; Belongs to the DEAD box helicase family. SrmB subfamily. | Putative RNA pseudouridylate synthase-family protein; Responsible for synthesis of pseudouridine from uracil-2605 in 23S ribosomal RNA; Belongs to the pseudouridine synthase RsuA family. | 0.659 |
rbaB | rluC | YPO2708 | YPO1591 | ATP-dependent RNA helicase; DEAD-box RNA helicase involved in the assembly of the 50S ribosomal subunit at low temperature. Exhibits RNA-stimulated ATP hydrolysis and RNA unwinding activity; Belongs to the DEAD box helicase family. SrmB subfamily. | Ribosomal large subunit pseudouridine synthase C; Responsible for synthesis of pseudouridine from uracil at positions 955, 2504 and 2580 in 23S ribosomal RNA; Belongs to the pseudouridine synthase RluA family. | 0.651 |
rbaB | rppH | YPO2708 | YPO0786 | ATP-dependent RNA helicase; DEAD-box RNA helicase involved in the assembly of the 50S ribosomal subunit at low temperature. Exhibits RNA-stimulated ATP hydrolysis and RNA unwinding activity; Belongs to the DEAD box helicase family. SrmB subfamily. | Conserved hypothetical protein; Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage; Belongs to the Nudix hydrolase family. RppH subfamily. | 0.598 |
rlmL | engA | YPO1418 | YPO2875 | Conserved hypothetical protein; Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA. Belongs to the methyltransferase superfamily. RlmKL family. | Putative GTP-binding protein; GTPase that plays an essential role in the late steps of ribosome biogenesis; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family. | 0.486 |
rlmL | rbaB | YPO1418 | YPO2708 | Conserved hypothetical protein; Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA. Belongs to the methyltransferase superfamily. RlmKL family. | ATP-dependent RNA helicase; DEAD-box RNA helicase involved in the assembly of the 50S ribosomal subunit at low temperature. Exhibits RNA-stimulated ATP hydrolysis and RNA unwinding activity; Belongs to the DEAD box helicase family. SrmB subfamily. | 0.576 |
rlmL | rluB | YPO1418 | YPO2213 | Conserved hypothetical protein; Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA. Belongs to the methyltransferase superfamily. RlmKL family. | Putative RNA pseudouridylate synthase-family protein; Responsible for synthesis of pseudouridine from uracil-2605 in 23S ribosomal RNA; Belongs to the pseudouridine synthase RsuA family. | 0.778 |
rlmL | rluC | YPO1418 | YPO1591 | Conserved hypothetical protein; Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA. Belongs to the methyltransferase superfamily. RlmKL family. | Ribosomal large subunit pseudouridine synthase C; Responsible for synthesis of pseudouridine from uracil at positions 955, 2504 and 2580 in 23S ribosomal RNA; Belongs to the pseudouridine synthase RluA family. | 0.585 |
rlmL | trmB | YPO1418 | YPO0951 | Conserved hypothetical protein; Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA. Belongs to the methyltransferase superfamily. RlmKL family. | Putative methyltransferase; Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA; Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family. | 0.424 |
rlmL | xth | YPO1418 | YPO2168 | Conserved hypothetical protein; Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA. Belongs to the methyltransferase superfamily. RlmKL family. | Similar to Escherichia coli exodeoxyribonuclease III XthA SW:EX3_ECOLI (P09030) (268 aa) fasta scores: E(): 0,80.1% id in 266 aa, and to Salmonella typhimurium exodeoxyribonuclease III XthA SW:EX3_SALTY (Q9Z612) (268 aa) fasta scores: E(): 0, 78.6% id in 266 aa. | 0.597 |
rlmN | engA | YPO2882 | YPO2875 | Conserved hypothetical protein; Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs. m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity; Belongs to the radical SAM superfamily. RlmN family. | Putative GTP-binding protein; GTPase that plays an essential role in the late steps of ribosome biogenesis; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family. | 0.577 |