STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
YPO2285Similar to the C-terminal regions of Escherichia coli D-ribose-binding periplasmic protein precursor RbsB SW:RBSB_ECOLI (P02925) (296 aa) fasta scores: E(): 7.4e-15,35.359% id in 181 aa, and Rhizobium loti ribose ABC transporter, periplasmic ribose-binding protein MLL7014 TR:BAB53199 (EMBL:AP003010) (313 aa) fasta scores: E(): 1e-34, 53.266% id in 199 aa. The CDS appears to be truncated at the N-terminus, identity with other proteins extends upstream of the start codon. Probable gene remnant; was marked partial. (208 aa)    
Predicted Functional Partners:
rbsC-2
Putative sugar ABC transporter, permease protein; Similar to Escherichia coli ribose transport system permease protein RbsC SW:RBSC_ECOLI (P04984) (321 aa) fasta scores: E(): 0, 40.8% id in 316 aa, and to Bacillus subtilis membrane transport protein RbsC TR:P96731 (EMBL:Z92953) (322 aa) fasta scores: E(): 0, 43.9% id in 321 aa.
 
 0.953
barA
Two-component regulatory protein; Similar to Escherichia coli sensor protein BarA SW:BARA_ECOLI (P26607) (918 aa) fasta scores: E(): 0, 61.6% id in 928 aa, and to Erwinia carotovora subsp. carotovora sensor/regulator protein RpfA TR:O08235 (EMBL:U62023) (929 aa) fasta scores: E(): 0, 59.7% id in 938 aa.
  
 0.950
arcB
Similar to Escherichia coli aerobic respiration control sensor protein ArcB SW:ARCB_ECOLI (P22763) (776 aa) fasta scores: E(): 0, 75.9% id in 781 aa, and to Vibrio cholerae sensor histidine kinase FexB or VC2369 TR:Q9KPJ8 (EMBL:AE004307) (785 aa) fasta scores: E(): 0, 58.8% id in 779 aa.
  
 0.945
YPO3965
Probable hybrid two-component system regulatory protein. CDS contains both sensor histidine kinase domain and response regulator receiver domain. C-terminus is similar to Rhizobium leguminosarum regulatory protein FixL TR:Q52824 (EMBL:Z70305) (641 aa) fasta scores: E(): 0,33.3% id in 519 aa, and to Pseudomonas syringae histidine protein kinase-response regulator hybrid protein CvgsY TR:Q9WWH9 (EMBL:AF133262) (671 aa) fasta scores: E(): 0,44.6% id in 383 aa.
   
 0.871
YPO0256
Two-component sensor/regulator; Similar to Salmonella typhimurium pathogenicity island regulator gene SpiR TR:P74862 (EMBL:U51927) (823 aa) fasta scores: E(): 0, 46.5% id in 826 aa and to Vibrio cholerae sensory box sensor histidine kinase/response regulator VieS VC1653 TR:Q9KRI8 (EMBL:AE004243) (1146 aa) fasta scores: E(): 0, 30.4% id in 559 aa. This CDS carries both the sensor and response regulator domains.
    
 0.861
rcsC
Two component sensor kinase/response regulator protein RcsC; Component of the Rcs signaling system, which controls transcription of numerous genes. RcsC functions as a membrane- associated protein kinase that phosphorylates RcsD in response to environmental signals. The phosphoryl group is then transferred to the response regulator RcsB.
    
 0.861
YPO3331
Putative sugar ABC transporter, permease protein; Similar to Escherichia coli ribose transport system permease protein RbsC SW:RBSC_ECOLI (P04984) (321 aa) fasta scores: E(): 2.2e-30, 34.2% id in 301 aa, and to Bacillus subtilis membrane transport protein RbsC TR:P96731 (EMBL:Z92953) (322 aa) fasta scores: E(): 7.9e-33, 35.4% id in 302 aa.
 
 0.841
YPO2583
Similar to Escherichia coli ribose transport system permease protein RbsC SW:RBSC_ECOLI (P04984) (321 aa) fasta scores: E(): 0, 45.9% id in 307 aa, and to Vibrio cholerae possible ribose ABC transporter, permease protein VCA0129 TR:Q9KN36 (EMBL:AE004354) (332 aa) fasta scores: E(): 0,44.6% id in 307 aa.
 
 0.824
YPO3332
Putative sugar ABC transporter, permease protein; Similar to Bacillus subtilis ribose transport system permease protein RbsC SW:RBSC_BACSU (P36948) (323 aa) fasta scores: E(): 5.3e-25, 31.6% id in 320 aa, and to Vibrio cholerae ribose ABC transporter, permease protein Vca0129 TR:Q9KN36 (EMBL:AE004354) (332 aa) fasta scores: E(): 1.4e-21, 29.8% id in 305 aa.
 
 0.816
rbsC
Similar to Bacillus subtilis ribose transport system permease protein RbsC SW:RBSC_BACSU (P36948) (323 aa) fasta scores: E(): 0, 48.8% id in 322 aa, and to Escherichia coli ribose transport system permease protein RbsC SW:RBSC_ECOLI (P04984) (321 aa) fasta scores: E(): 0, 47.1% id in 325 aa.
 
  0.797
Your Current Organism:
Yersinia pestis
NCBI taxonomy Id: 214092
Other names: Y. pestis CO92, Yersinia pestis CO92, Yersinia pestis str. CO92, Yersinia pestis strain CO92
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