STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
dalDPutative mannitol dehydrogenase; Similar to Klebsiella pneumoniae D-arabinitol dehydrogenase DalD TR:O52720 (EMBL:AF045245) (455 aa) fasta scores: E(): 0, 64.4% id in 449 aa, and to Rhodobacter sphaeroides mannitol 2-dehydrogenase MtlK SW:MTLK_RHOSH (P33216) (476 aa) fasta scores: E(): 0, 34.0% id in 438 aa. (463 aa)    
Predicted Functional Partners:
mtlA
Similar to Escherichia coli PTS system,mannitol-specific IIABC component MtlA SW:PTMA_ECOLI (P00550) (637 aa) fasta scores: E(): 0, 81.7% id in 638 aa,and to Klebsiella pneumoniae PTS system, mannitol-specific IIABC component MtlA SW:PTMA_KLEPN (Q9XBM7) (635 aa) fasta scores: E(): 0, 81.1% id in 635 aa.
  
 
 0.971
fpr-2
Fpr protein; Similar to Salmonella typhimurium PTS system,fructose-specific IIa/FPr component FruB SW:PTFA_SALTY (P17127) (376 aa) fasta scores: E(): 0, 71.0% id in 376 aa,and to Escherichia coli PTS system, fructose-specific IIa/FPr component FruB SW:PTFA_ECOLI (P24217) (376 aa) fasta scores: E(): 0, 69.4% id in 376 aa.
  
 
 0.868
YPO0405
Similar to e.g. Escherichia coli phosphoenolpyruvate-protein phosphotransferase PtsI,SW:PT1_ECOLI (P08839) (575 aa) fasta scores: E(): 0, 36.0% id in 583 aa, but has both N- and C-terminal extensions. Also similar to Escherichia coli phosphoenolpyruvate-protein phosphotransferase PtsA,SW:PT1A_ECOLI (P32670) (711 aa) fasta scores: E(): 0, 64.5% id in 726 aa and to Escherichia coli putative phosphoenolpyruvate-protein phosphotransferase YpdD,SW:YPDD_ECOLI (P77439) (831 aa) fasta scores: E(): 0, 41.5% id in 853 aa.
  
 
 0.732
uxaA
Similar to Escherichia coli altronate hydrolase UxaA SW:UXAA_ECOLI (P42604) (495 aa) fasta scores: E(): 0, 78.8% id in 496 aa, and to Bacillus subtilis altronate hydrolase SW:UXAA_BACSU (O34673) (497 aa) fasta scores: E(): 0, 58.8% id in 497 aa.
 
 
 0.729
fruA
Similar to Escherichia coli PTS system,fructose-specific IIBC component FruA or PtsF SW:PTFB_ECOLI (P20966) (563 aa) fasta scores: E(): 0, 77.2% id in 569 aa,and to Vibrio cholerae PTS system, fructose-specific IIBC component VCA0516 TR:Q9KM72 (EMBL:AE004382) (580 aa) fasta scores: E(): 0, 65.7% id in 531 aa.
  
 
 0.707
uxuA
Mannonate dehydratase; Catalyzes the dehydration of D-mannonate; Belongs to the mannonate dehydratase family.
 
 
 0.668
uxaC
Uronate isomerase; Similar to Escherichia coli uronate isomerase UxaC SW:UXAC_ECOLI (P42607) (470 aa) fasta scores: E(): 0, 83.2% id in 469 aa, and to Bacillus subtilis uronate isomerase UxaC SW:UXAC_BACSU (O34808) (473 aa) fasta scores: E(): 0,52.1% id in 468 aa.
 
 
 0.655
manC
Similar to Yersinia pseudotuberculosis mannose-1-phosphate guanylyltransferase ManC TR:Q9RCB1 (EMBL:AJ251712) (468 aa) fasta scores: E(): 0, 99.8% id in 468 aa, and to Yersinia enterocolitica mannose-1-phosphate guanylyltransferase RfbM or ManC TR:Q56874 (EMBL:U46859) (465 aa) fasta scores: E(): 0, 80.7% id in 462 aa, and identical to the previously sequenced Yersinia pestis mannose-1-phosphate guanylyltransferase ManC TR:Q9RCC5 (EMBL:AJ251713) (468 aa) fasta scores: E(): 0, 100.0% id in 468 aa; Belongs to the mannose-6-phosphate isomerase type 2 family.
    
 0.593
YPO2324
Putative transcriptional regulatory protein; Similar to Klebsiella pneumoniae repressor DalR TR:O52721 (EMBL:AF045245) (313 aa) fasta scores: E(): 0,44.9% id in 312 aa, and to Bacillus subtilis deoxyribonucleoside regulator DeoR SW:DEOR_BACSU (P39140) (313 aa) fasta scores: E(): 2.9e-17, 26.6% id in 316 aa.
 
    0.580
xylB
Xylulose kinase; Similar to Escherichia coli xylulose kinase XylB SW:XYLB_ECOLI (P09099) (484 aa) fasta scores: E(): 0, 72.0% id in 482 aa, and to Klebsiella pneumoniae xylulose kinase XylB SW:XYLB_KLEPN (P29444) (483 aa) fasta scores: E(): 0,66.4% id in 482 aa.
 
  
 0.561
Your Current Organism:
Yersinia pestis
NCBI taxonomy Id: 214092
Other names: Y. pestis CO92, Yersinia pestis CO92, Yersinia pestis str. CO92, Yersinia pestis strain CO92
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