STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ureCUrease alpha subunit; Previously sequenced as Yersinia pestis urease alpha subunit UreC SW:URE1_YERPE (Q9ZFR9) (571 aa) fasta scores: E(): 0, 100.0% id in 571 aa. Similar to Yersinia pseudotuberculosis urease alpha subunit ureC SW:URE1_YERPS (P52313) (571 aa) fasta scores: E(): 0, 99.8% id in 571 aa,and to Yersinia enterocolitica urease alpha subunit UreC SW:URE1_YEREN (P31494) (571 aa) fasta scores: E(): 0, 97.2% id in 571 aa; Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family. (572 aa)    
Predicted Functional Partners:
ureA
Urease gamma subunit; Previously sequenced as Yersinia pestis urease gamma subunit UreA SW:URE3_YERPS (P52315) (100 aa) fasta scores: E(): 0, 100.0% id in 100 aa. Identical to the Yersinia pseudotuberculosis urease gamma subunit UreA, and similar to Yersinia enterocolitica urease gamma subunit UreA SW:URE3_YEREN (P31496) (100 aa) fasta scores: E(): 0, 99.0% id in 100 aa.
 0.999
ureB
Urease beta subunit; Previously sequenced as Yersinia pestis urease beta subunit UreB SW:URE2_YERPS (P52314) (144 aa) fasta scores: E(): 0, 100.0% id in 144 aa. Identical to the Yersinia pseudotuberculosis urease gamma subunit UreB, and similar to Yersinia enterocolitica urease beta subunit UreB SW:URE2_YEREN (P31495) (163 aa) fasta scores: E(): 0, 90.7% id in 140 aa.
 0.999
ureE
Urease accessory protein; Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly. Belongs to the UreE family.
 
  
 0.998
ureF
Urease accessory protein; Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
 
 
 0.998
ureG
Urease accessory protein; Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG.
 
  
 0.991
ureD
Pfam match to entry PF01774 UreD, UreD urease accessory protein, score 266.50, E-value 3.4e-76.
 
  
 0.804
YPO1187
Putative substrate-binding periplasmic transport protein; Similar to Bacillus halodurans ABC transporter BH0251 TR:Q9KG62 (EMBL:AP001507) (419 aa) fasta scores: E(): 0, 52.6% id in 378 aa, and to Pseudomonas aeruginosa aliphatic amidase expression-regulating protein Amic or PA3364 SW:AMIC_PSEAE (P27017) (384 aa) fasta scores: E(): 2.3e-24, 28.6% id in 371 aa.
 
   
 0.479
ymoA
Modulating protein YmoA (histone-like protein); Modulates the thermoregulation of VirF, and hence the yop regulon, as well as the expression of the enterotoxin gene yst. Involved in chromosome structure and DNA topology; probably by means of compaction of DNA in conjunction with H-NS; probably requires H-NS to bind DNA (By similarity); Belongs to the Hha/YmoA/Cnu family.
      
 0.476
YPO2699
Similar to Escherichia coli hypothetical protein YbgJ SW:YBGJ_ECOLI (P75744) (218 aa) fasta scores: E(): 0,71.1% id in 218 aa, and to Haemophilus influenzae hypothetical protein HI1731 SW:YBGJ_HAEIN (P44299) (213 aa) fasta scores: E(): 0, 48.3% id in 209 aa. Contains a nonsense mutation (amber) at codon 182 which results in the deletion of 35 C-terminal amino acids. Effect on the function of the protein is unknown. The sequence has been checked and is believed to be correct.
   
 
 0.441
YPO1190
Putative ABC transport ATP-binding subunit; Similar to Bacillus halodurans ABC transporter BH0248 TR:Q9KG65 (EMBL:AP001507) (267 aa) fasta scores: E(): 0, 49.4% id in 255 aa, and to Escherichia coli high-affinity branched-chain amino acid transport ATP-binding protein LivG SW:LIVG_ECOLI (P22730) (255 aa) fasta scores: E(): 4.4e-23, 36.5% id in 252 aa.
 
  
 0.438
Your Current Organism:
Yersinia pestis
NCBI taxonomy Id: 214092
Other names: Y. pestis CO92, Yersinia pestis CO92, Yersinia pestis str. CO92, Yersinia pestis strain CO92
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