STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
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[Homology]
Score
kdpAPutative potassium-transporting ATPase A chain; Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane. (562 aa)    
Predicted Functional Partners:
kdpC
Putative potassium-transporting ATPase C chain; Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP-binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB/KdpC/ATP ternary complex.
 0.999
kdpB
Putative potassium-transporting ATPase B chain; Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system. Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IA subfamily.
 
 
 0.999
kdpD
Similar to Escherichia coli sensor protein KdpD SW:KDPD_ECOLI (P21865) (894 aa) fasta scores: E(): 0, 71.2% id in 891 aa, and to Clostridium acetobutylicum sensor protein KdpD SW:KDPD_CLOAB (P94608) (900 aa) fasta scores: E(): 0, 36.1% id in 914 aa.
 
  
 0.979
kdpE
Similar to Escherichia coli kdp operon transcriptional regulatory protein KdpE SW:KDPE_ECOLI (P21866) (225 aa) fasta scores: E(): 0, 75.0% id in 208 aa,and to Pseudomonas aeruginosa two-component response regulator KdpE TR:AAG05026 (EMBL:AE004591) (230 aa) fasta scores: E(): 0, 51.7% id in 209 aa. CDS is truncated at the N-terminus in comparison to other orthologues. Upstream inframe amino acids are similar to the N-terminus of orthologues, but there is no translational start.
 
  
 0.841
rstB
Two-component regulatory system, sensor kinase protein; Similar to Escherichia coli sensor protein RstB SW:RSTB_ECOLI (P18392) (433 aa) fasta scores: E(): 0, 69.5% id in 419 aa, and to Escherichia coli sensor protein CpxA SW:CPXA_ECOLI (P08336) (457 aa) fasta scores: E(): 2.5e-27,28.4% id in 450 aa.
  
  
 0.754
kup
Potassium transport protein; Responsible for the low-affinity transport of potassium into the cell, with the probable concomitant uptake of protons (symport system); Belongs to the HAK/KUP transporter (TC 2.A.72) family.
   
  
 0.699
htpX
Putative heat shock protein; Similar to Escherichia coli probable protease HtpX SW:HTPX_ECOLI (P23894) (293 aa) fasta scores: E(): 0, 87.0% id in 293 aa, and to Vibrio cholerae heat shock protein HtpX vc1117 TR:Q9KSY9 (EMBL:AE004192) (287 aa) fasta scores: E(): 0, 69.9% id in 292 aa; Belongs to the peptidase M48B family.
      
 0.507
Your Current Organism:
Yersinia pestis
NCBI taxonomy Id: 214092
Other names: Y. pestis CO92, Yersinia pestis CO92, Yersinia pestis str. CO92, Yersinia pestis strain CO92
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