STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
cpdPPutative 3',5'-cyclic-nucleotide phosphodiesterase; Probable periplasmic protein cyclic-nucleotide phosphodiesterase. Similar to Vibrio fischeri 3',5'-cyclic-nucleotide phosphodiesterase CpdP SW:CPDP_VIBFI (Q56686) (330 aa) fasta scores: E(): 0, 46.6% id in 328 aa, and to Schizosaccharomyces pombe 3',5'-cyclic-nucleotide phosphodiesterase Cgs2 SW:CNA1_SCHPO (P36599) (346 aa) fasta scores: E(): 9.1e-16,28.0% id in 336 aa; Belongs to the cAMP phosphodiesterase class-II family. (343 aa)    
Predicted Functional Partners:
icc
Icc protein homologue; Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes.
     
 0.944
cyaB
Adenylate cyclase 2; Belongs to a family of thermophilic adenylate cyclases. Similar to Aeromonas hydrophila adenylate cyclase 2 CyaB TR:O69199 (EMBL:AJ223730) (190 aa) fasta scores: E(): 8.9e-33, 50.9% id in 175 aa.
  
  
  0.941
cya
Adenylate cyclase; Previously sequenced as Yersinia pestis adenylate cyclase Cya SW:CYAA_YERPE (P40127) (850 aa) fasta scores: E(): 0, 99.3% id in 850 aa. Sequence varies from the database entry at 5 residues. CDS is similar to Escherichia coli adenylate cyclase CyaA SW:CYAA_ECOLI (P00936) (848 aa) fasta scores: E(): 0, 83.5% id in 831 aa.
     
 0.936
amn
Putative AMP nucleosidase; Catalyzes the hydrolysis of the N-glycosidic bond of AMP to form adenine and ribose 5-phosphate. Involved in regulation of AMP concentrations.
   
 
  0.933
YPO1033
Similar to Escherichia coli hypothetical protein YgdH SW:YGDH_ECOLI (P37350) (454 aa) fasta scores: E(): 0,82.6% id in 454 aa, and to Vibrio cholerae hypothetical protein VC0899 TR:Q9KTK3 (EMBL:AE004173) (457 aa) fasta scores: E(): 0, 69.9% id in 455 aa.
   
 
  0.932
phr
Similar to Escherichia coli deoxyribodipyrimidine photolyase PhrB SW:PHR_ECOLI (P00914) (472 aa) fasta scores: E(): 0, 60.2% id in 475 aa, and to Vibrio cholerae deoxyribodipyrimidine photolyase VCA0057 TR:Q9KNA8 (EMBL:AE004349) (469 aa) fasta scores: E(): 0, 51.4% id in 477 aa; Belongs to the DNA photolyase family.
  
    0.796
YPO2884
Putative exported protein; No significant database matches.
  
    0.572
YPO2697
Similar to Escherichia coli hypothetical protein YbgI SW:YBGI_ECOLI (P75743) (247 aa) fasta scores: E(): 0,69.2% id in 247 aa, and to C-terminal region of Haemophilus influenzae protein HI0105 SW:YBGI_HAEIN (Q57354) (279 aa) fasta scores: E(): 0, 60.7% id in 252 aa.
  
    0.561
YPO2857
Putative exported protein; Poor database matches. Similar to Escherichia coli hypothetical protein YkfE TR:BAA77890 (EMBL:D83536) (157 aa) fasta scores: E(): 9.2e-08, 31.6% id in 152 aa.
  
     0.517
YPO1192
Conserved hypothetical protein; Weakly similar to others of unknown function Bacillus halodurans BH2933 protein BH2933 TR:Q9K8S0 (EMBL:AP001517) (269 aa) fasta scores: E(): 2e-09, 26.8% id in 284 aa, and to Nostoc sp. GSV224 hypothetical protein TR:Q9RAH0 (EMBL:AF204805) (265 aa) fasta scores: E(): 0.12,22.3% id in 292 aa.
  
    0.497
Your Current Organism:
Yersinia pestis
NCBI taxonomy Id: 214092
Other names: Y. pestis CO92, Yersinia pestis CO92, Yersinia pestis str. CO92, Yersinia pestis strain CO92
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.