STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
yegBPutative membrane protein; Similar to the N-terminal region of Escherichia coli multidrug resistance protein B emrB SW:EMRB_ECOLI (P27304) (512 aa) fasta scores: E(): 9.9e-30, 31.1% id in 399 aa,and to Escherichia coli hypothetical protein YegB SW:YEGB_ECOLI (P36554) (471 aa) fasta scores: E(): 0, 71.8% id in 465 aa. (465 aa)    
Predicted Functional Partners:
emrA
Similar to Escherichia coli multidrug resistance protein A EmrA SW:EMRA_ECOLI (P27303) (390 aa) fasta scores: E(): 0, 69.7% id in 389 aa, and to Haemophilus influenzae multidrug resistance protein A homolog EmrA or Hi0898 SW:EMRA_HAEIN (P44928) (390 aa) fasta scores: E(): 0, 47.8% id in 389 aa.
 
 
 0.939
yegO
AcrB/AcrD/AcrF family membrane protein; Similar to Escherichia coli hypothetical protein YegO SW:YEGO_ECOLI (P76399) (1025 aa) fasta scores: E(): 0,80.1% id in 1019 aa, and to Pseudomonas aeruginosa probable RND efflux transporter PA2526 TR:AAG05914 (EMBL:AE004680) (1036 aa) fasta scores: E(): 0, 61.7% id in 1019 aa. Similar to YPO2848 (50.6% identity in 1018 aa overlap); Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family. MdtC subfamily.
  
  
 0.853
yegN
AcrB/AcrD/AcrF family membrane protein; Similar to Pseudomonas aeruginosa multidrug efflux transporter AmrB TR:AAG05406 (EMBL:AF147719) (1045 aa) fasta scores: E(): 0, 29.8% id in 1053 aa, and to Escherichia coli hypothetical protein YegN SW:YEGN_ECOLI (P76398) (1040 aa) fasta scores: E(): 0, 81.4% id in 1039 aa. Similar to YPO2849 (50.5% identity in 1018 aa overlap); Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family. MdtB subfamily.
  
  
 0.805
yegM
Putitive HlyD family secretion protein; Similar to Escherichia coli acriflavin resistance protein E AcrE SW:ACRE_ECOLI (P24180) (385 aa) fasta scores: E(): 1.2e-26, 31.3% id in 361 aa, and to Escherichia coli hypothetical protein YegM SW:YEGM_ECOLI (P76397) (415 aa) fasta scores: E(): 0, 64.5% id in 409 aa; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
  
  
 0.751
irp1
Previously sequenced as Yersinia pestis yersiniabactin biosynthetic protein Irp1 TR:Q9Z373 (EMBL:AL031866) (3163 aa) fasta scores: E(): 0, 100.0% id in 3163 aa. Similar to Yersinia enterocolitica HMWP1 protein Irp1 TR:O54511 (EMBL:Y12527) (3161 aa) fasta scores: E(): 0, 97.9% id in 3163 aa.
  
 
 0.597
YPO1940
Putative membrane protein; Previously sequenced as Yersinia pestis hypothetical protein TR:Q9ZC50 (EMBL:AL031866) (546 aa) fasta scores: E(): 0, 100.0% id in 546 aa. Similar to Bacillus subtilis hypothetical protein YfiU TR:O31563 (EMBL:Z99108) (518 aa) fasta scores: E(): 3.8e-13, 25.3% id in 538 aa.
  
     0.496
appA
Similar to many cytochrome B fragments found in various genetic backgrounds: Urocampus carinirostris cytochrome B (fragment) CytB TR:Q9MI83 (EMBL:AF155468) (100 aa) fasta scores: E(): 1.5, 32.3% id in 65 aa, and to Apistogramma caetei cytochrome B (fragment) CytB TR:CAC16341 (EMBL:AJ297670) (115 aa) fasta scores: E(): 2,34.3% id in 67 aa.
   
  
 0.474
yhcQ
Putative HlyD family secretion protein; Forms an efflux pump with AaeB; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
  
 
 0.472
YPO0619
Putative HlyD family secretion protein; Similar to Escherichia coli hypothetical protein YjcR SW:YJCR_ECOLI (P32716) (343 aa) fasta scores: E(): 0,38.3% id in 332 aa, and to Neisseria meningitidis possible fatty acid efflux system protein NMB0318 TR:Q9K160 (EMBL:AE002389) (384 aa) fasta scores: E(): 4.2e-17, 29.4% id in 350 aa.
  
 
 0.459
bacA
Putative bacitracin resistance protein; Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin; Belongs to the UppP family.
   
  
 0.432
Your Current Organism:
Yersinia pestis
NCBI taxonomy Id: 214092
Other names: Y. pestis CO92, Yersinia pestis CO92, Yersinia pestis str. CO92, Yersinia pestis strain CO92
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