node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
YPO1458 | YPO1459 | YPO1458 | YPO1459 | Similar to Homo sapiens mitochondria enoyl-CoA hydratase ECHS1 SW:ECHM_HUMAN (P30084) (290 aa) fasta scores: E(): 1.2e-07, 27.8% id in 198 aa, and to Amycolatopsis orientalis putative vancomycin biosynthesis protein PCZA361.9 TR:O52797 (EMBL:AJ223998) (267 aa) fasta scores: E(): 1.8e-08, 27.2% id in 235 aa. | Putative enoyl-CoA hydratase; Similar to an internal region of Rattus norvegicus mitochondrial enoyl-CoA hydratase ECHS1 SW:ECHM_RAT (P14604) (290 aa) fasta scores: E(): 1.5e-13, 25.2% id in 238 aa, and to Bacillus subtilis putative polyketide biosynthesis enoyl-CoA hydratase homolog PksI SW:PKSI_BACSU (P40802) (249 aa) fasta scores: E(): 7.3e-24, 33.5% id in 248 aa. | 0.989 |
YPO1458 | fabV | YPO1458 | YPO4104 | Similar to Homo sapiens mitochondria enoyl-CoA hydratase ECHS1 SW:ECHM_HUMAN (P30084) (290 aa) fasta scores: E(): 1.2e-07, 27.8% id in 198 aa, and to Amycolatopsis orientalis putative vancomycin biosynthesis protein PCZA361.9 TR:O52797 (EMBL:AJ223998) (267 aa) fasta scores: E(): 1.8e-08, 27.2% id in 235 aa. | Conserved hypothetical protein; Involved in the final reduction of the elongation cycle of fatty acid synthesis (FAS II). Catalyzes the reduction of a carbon- carbon double bond in an enoyl moiety that is covalently linked to an acyl carrier protein (ACP). | 0.416 |
YPO1458 | fadA | YPO1458 | YPO3767 | Similar to Homo sapiens mitochondria enoyl-CoA hydratase ECHS1 SW:ECHM_HUMAN (P30084) (290 aa) fasta scores: E(): 1.2e-07, 27.8% id in 198 aa, and to Amycolatopsis orientalis putative vancomycin biosynthesis protein PCZA361.9 TR:O52797 (EMBL:AJ223998) (267 aa) fasta scores: E(): 1.8e-08, 27.2% id in 235 aa. | 3-ketoacyl-CoA thiolase; Catalyzes the final step of fatty acid oxidation in which acetyl-CoA is released and the CoA ester of a fatty acid two carbons shorter is formed. Involved in the aerobic and anaerobic degradation of long-chain fatty acids (By similarity). | 0.990 |
YPO1458 | fadB | YPO1458 | YPO3766 | Similar to Homo sapiens mitochondria enoyl-CoA hydratase ECHS1 SW:ECHM_HUMAN (P30084) (290 aa) fasta scores: E(): 1.2e-07, 27.8% id in 198 aa, and to Amycolatopsis orientalis putative vancomycin biosynthesis protein PCZA361.9 TR:O52797 (EMBL:AJ223998) (267 aa) fasta scores: E(): 1.8e-08, 27.2% id in 235 aa. | Fatty acid oxidation complex alpha subunit; Involved in the aerobic and anaerobic degradation of long- chain fatty acids via beta-oxidation cycle. Catalyzes the formation of 3-oxoacyl-CoA from enoyl-CoA via L-3-hydroxyacyl-CoA. It can also use D-3-hydroxyacyl-CoA and cis-3-enoyl-CoA as substrate. In the C-terminal section; belongs to the 3-hydroxyacyl-CoA dehydrogenase family. | 0.943 |
YPO1458 | fadI-2 | YPO1458 | YPO2746 | Similar to Homo sapiens mitochondria enoyl-CoA hydratase ECHS1 SW:ECHM_HUMAN (P30084) (290 aa) fasta scores: E(): 1.2e-07, 27.8% id in 198 aa, and to Amycolatopsis orientalis putative vancomycin biosynthesis protein PCZA361.9 TR:O52797 (EMBL:AJ223998) (267 aa) fasta scores: E(): 1.8e-08, 27.2% id in 235 aa. | Putative 3-ketoacyl-CoA thiolase; Catalyzes the final step of fatty acid oxidation in which acetyl-CoA is released and the CoA ester of a fatty acid two carbons shorter is formed. | 0.990 |
YPO1458 | faoA | YPO1458 | YPO2747 | Similar to Homo sapiens mitochondria enoyl-CoA hydratase ECHS1 SW:ECHM_HUMAN (P30084) (290 aa) fasta scores: E(): 1.2e-07, 27.8% id in 198 aa, and to Amycolatopsis orientalis putative vancomycin biosynthesis protein PCZA361.9 TR:O52797 (EMBL:AJ223998) (267 aa) fasta scores: E(): 1.8e-08, 27.2% id in 235 aa. | Putative fatty oxidation complex alpha subunit,enoyl-CoA hydratase; Catalyzes the formation of a hydroxyacyl-CoA by addition of water on enoyl-CoA. Also exhibits 3-hydroxyacyl-CoA epimerase and 3- hydroxyacyl-CoA dehydrogenase activities; In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family. | 0.945 |
YPO1458 | irp1 | YPO1458 | YPO1910 | Similar to Homo sapiens mitochondria enoyl-CoA hydratase ECHS1 SW:ECHM_HUMAN (P30084) (290 aa) fasta scores: E(): 1.2e-07, 27.8% id in 198 aa, and to Amycolatopsis orientalis putative vancomycin biosynthesis protein PCZA361.9 TR:O52797 (EMBL:AJ223998) (267 aa) fasta scores: E(): 1.8e-08, 27.2% id in 235 aa. | Previously sequenced as Yersinia pestis yersiniabactin biosynthetic protein Irp1 TR:Q9Z373 (EMBL:AL031866) (3163 aa) fasta scores: E(): 0, 100.0% id in 3163 aa. Similar to Yersinia enterocolitica HMWP1 protein Irp1 TR:O54511 (EMBL:Y12527) (3161 aa) fasta scores: E(): 0, 97.9% id in 3163 aa. | 0.922 |
YPO1458 | nifJ | YPO1458 | YPO2334 | Similar to Homo sapiens mitochondria enoyl-CoA hydratase ECHS1 SW:ECHM_HUMAN (P30084) (290 aa) fasta scores: E(): 1.2e-07, 27.8% id in 198 aa, and to Amycolatopsis orientalis putative vancomycin biosynthesis protein PCZA361.9 TR:O52797 (EMBL:AJ223998) (267 aa) fasta scores: E(): 1.8e-08, 27.2% id in 235 aa. | Similar to Escherichia coli probable pyruvate-flavodoxin oxidoreductase YdbK SW:NIFJ_ECOLI (P52647) (1174 aa) fasta scores: E(): 0, 80.5% id in 1177 aa, and to Klebsiella pneumoniae pyruvate-flavodoxin oxidoreductase NifJ SW:NIFJ_KLEPN (P03833) (1171 aa) fasta scores: E(): 0, 48.0% id in 1184 aa. | 0.882 |
YPO1458 | yafH | YPO1458 | YPO3244 | Similar to Homo sapiens mitochondria enoyl-CoA hydratase ECHS1 SW:ECHM_HUMAN (P30084) (290 aa) fasta scores: E(): 1.2e-07, 27.8% id in 198 aa, and to Amycolatopsis orientalis putative vancomycin biosynthesis protein PCZA361.9 TR:O52797 (EMBL:AJ223998) (267 aa) fasta scores: E(): 1.8e-08, 27.2% id in 235 aa. | Probable acyl-CoA dehydrogenase; Catalyzes the dehydrogenation of acyl-coenzymes A (acyl-CoAs) to 2-enoyl-CoAs, the first step of the beta-oxidation cycle of fatty acid degradation. Is required for the utilization of medium- and long- chain fatty acids as sole carbon sources for growth. | 0.956 |
YPO1459 | YPO1458 | YPO1459 | YPO1458 | Putative enoyl-CoA hydratase; Similar to an internal region of Rattus norvegicus mitochondrial enoyl-CoA hydratase ECHS1 SW:ECHM_RAT (P14604) (290 aa) fasta scores: E(): 1.5e-13, 25.2% id in 238 aa, and to Bacillus subtilis putative polyketide biosynthesis enoyl-CoA hydratase homolog PksI SW:PKSI_BACSU (P40802) (249 aa) fasta scores: E(): 7.3e-24, 33.5% id in 248 aa. | Similar to Homo sapiens mitochondria enoyl-CoA hydratase ECHS1 SW:ECHM_HUMAN (P30084) (290 aa) fasta scores: E(): 1.2e-07, 27.8% id in 198 aa, and to Amycolatopsis orientalis putative vancomycin biosynthesis protein PCZA361.9 TR:O52797 (EMBL:AJ223998) (267 aa) fasta scores: E(): 1.8e-08, 27.2% id in 235 aa. | 0.989 |
YPO1459 | fabV | YPO1459 | YPO4104 | Putative enoyl-CoA hydratase; Similar to an internal region of Rattus norvegicus mitochondrial enoyl-CoA hydratase ECHS1 SW:ECHM_RAT (P14604) (290 aa) fasta scores: E(): 1.5e-13, 25.2% id in 238 aa, and to Bacillus subtilis putative polyketide biosynthesis enoyl-CoA hydratase homolog PksI SW:PKSI_BACSU (P40802) (249 aa) fasta scores: E(): 7.3e-24, 33.5% id in 248 aa. | Conserved hypothetical protein; Involved in the final reduction of the elongation cycle of fatty acid synthesis (FAS II). Catalyzes the reduction of a carbon- carbon double bond in an enoyl moiety that is covalently linked to an acyl carrier protein (ACP). | 0.413 |
YPO1459 | fadA | YPO1459 | YPO3767 | Putative enoyl-CoA hydratase; Similar to an internal region of Rattus norvegicus mitochondrial enoyl-CoA hydratase ECHS1 SW:ECHM_RAT (P14604) (290 aa) fasta scores: E(): 1.5e-13, 25.2% id in 238 aa, and to Bacillus subtilis putative polyketide biosynthesis enoyl-CoA hydratase homolog PksI SW:PKSI_BACSU (P40802) (249 aa) fasta scores: E(): 7.3e-24, 33.5% id in 248 aa. | 3-ketoacyl-CoA thiolase; Catalyzes the final step of fatty acid oxidation in which acetyl-CoA is released and the CoA ester of a fatty acid two carbons shorter is formed. Involved in the aerobic and anaerobic degradation of long-chain fatty acids (By similarity). | 0.989 |
YPO1459 | fadB | YPO1459 | YPO3766 | Putative enoyl-CoA hydratase; Similar to an internal region of Rattus norvegicus mitochondrial enoyl-CoA hydratase ECHS1 SW:ECHM_RAT (P14604) (290 aa) fasta scores: E(): 1.5e-13, 25.2% id in 238 aa, and to Bacillus subtilis putative polyketide biosynthesis enoyl-CoA hydratase homolog PksI SW:PKSI_BACSU (P40802) (249 aa) fasta scores: E(): 7.3e-24, 33.5% id in 248 aa. | Fatty acid oxidation complex alpha subunit; Involved in the aerobic and anaerobic degradation of long- chain fatty acids via beta-oxidation cycle. Catalyzes the formation of 3-oxoacyl-CoA from enoyl-CoA via L-3-hydroxyacyl-CoA. It can also use D-3-hydroxyacyl-CoA and cis-3-enoyl-CoA as substrate. In the C-terminal section; belongs to the 3-hydroxyacyl-CoA dehydrogenase family. | 0.702 |
YPO1459 | fadI-2 | YPO1459 | YPO2746 | Putative enoyl-CoA hydratase; Similar to an internal region of Rattus norvegicus mitochondrial enoyl-CoA hydratase ECHS1 SW:ECHM_RAT (P14604) (290 aa) fasta scores: E(): 1.5e-13, 25.2% id in 238 aa, and to Bacillus subtilis putative polyketide biosynthesis enoyl-CoA hydratase homolog PksI SW:PKSI_BACSU (P40802) (249 aa) fasta scores: E(): 7.3e-24, 33.5% id in 248 aa. | Putative 3-ketoacyl-CoA thiolase; Catalyzes the final step of fatty acid oxidation in which acetyl-CoA is released and the CoA ester of a fatty acid two carbons shorter is formed. | 0.988 |
YPO1459 | faoA | YPO1459 | YPO2747 | Putative enoyl-CoA hydratase; Similar to an internal region of Rattus norvegicus mitochondrial enoyl-CoA hydratase ECHS1 SW:ECHM_RAT (P14604) (290 aa) fasta scores: E(): 1.5e-13, 25.2% id in 238 aa, and to Bacillus subtilis putative polyketide biosynthesis enoyl-CoA hydratase homolog PksI SW:PKSI_BACSU (P40802) (249 aa) fasta scores: E(): 7.3e-24, 33.5% id in 248 aa. | Putative fatty oxidation complex alpha subunit,enoyl-CoA hydratase; Catalyzes the formation of a hydroxyacyl-CoA by addition of water on enoyl-CoA. Also exhibits 3-hydroxyacyl-CoA epimerase and 3- hydroxyacyl-CoA dehydrogenase activities; In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family. | 0.701 |
YPO1459 | irp1 | YPO1459 | YPO1910 | Putative enoyl-CoA hydratase; Similar to an internal region of Rattus norvegicus mitochondrial enoyl-CoA hydratase ECHS1 SW:ECHM_RAT (P14604) (290 aa) fasta scores: E(): 1.5e-13, 25.2% id in 238 aa, and to Bacillus subtilis putative polyketide biosynthesis enoyl-CoA hydratase homolog PksI SW:PKSI_BACSU (P40802) (249 aa) fasta scores: E(): 7.3e-24, 33.5% id in 248 aa. | Previously sequenced as Yersinia pestis yersiniabactin biosynthetic protein Irp1 TR:Q9Z373 (EMBL:AL031866) (3163 aa) fasta scores: E(): 0, 100.0% id in 3163 aa. Similar to Yersinia enterocolitica HMWP1 protein Irp1 TR:O54511 (EMBL:Y12527) (3161 aa) fasta scores: E(): 0, 97.9% id in 3163 aa. | 0.922 |
YPO1459 | nifJ | YPO1459 | YPO2334 | Putative enoyl-CoA hydratase; Similar to an internal region of Rattus norvegicus mitochondrial enoyl-CoA hydratase ECHS1 SW:ECHM_RAT (P14604) (290 aa) fasta scores: E(): 1.5e-13, 25.2% id in 238 aa, and to Bacillus subtilis putative polyketide biosynthesis enoyl-CoA hydratase homolog PksI SW:PKSI_BACSU (P40802) (249 aa) fasta scores: E(): 7.3e-24, 33.5% id in 248 aa. | Similar to Escherichia coli probable pyruvate-flavodoxin oxidoreductase YdbK SW:NIFJ_ECOLI (P52647) (1174 aa) fasta scores: E(): 0, 80.5% id in 1177 aa, and to Klebsiella pneumoniae pyruvate-flavodoxin oxidoreductase NifJ SW:NIFJ_KLEPN (P03833) (1171 aa) fasta scores: E(): 0, 48.0% id in 1184 aa. | 0.881 |
YPO1459 | yafH | YPO1459 | YPO3244 | Putative enoyl-CoA hydratase; Similar to an internal region of Rattus norvegicus mitochondrial enoyl-CoA hydratase ECHS1 SW:ECHM_RAT (P14604) (290 aa) fasta scores: E(): 1.5e-13, 25.2% id in 238 aa, and to Bacillus subtilis putative polyketide biosynthesis enoyl-CoA hydratase homolog PksI SW:PKSI_BACSU (P40802) (249 aa) fasta scores: E(): 7.3e-24, 33.5% id in 248 aa. | Probable acyl-CoA dehydrogenase; Catalyzes the dehydrogenation of acyl-coenzymes A (acyl-CoAs) to 2-enoyl-CoAs, the first step of the beta-oxidation cycle of fatty acid degradation. Is required for the utilization of medium- and long- chain fatty acids as sole carbon sources for growth. | 0.889 |
fabV | YPO1458 | YPO4104 | YPO1458 | Conserved hypothetical protein; Involved in the final reduction of the elongation cycle of fatty acid synthesis (FAS II). Catalyzes the reduction of a carbon- carbon double bond in an enoyl moiety that is covalently linked to an acyl carrier protein (ACP). | Similar to Homo sapiens mitochondria enoyl-CoA hydratase ECHS1 SW:ECHM_HUMAN (P30084) (290 aa) fasta scores: E(): 1.2e-07, 27.8% id in 198 aa, and to Amycolatopsis orientalis putative vancomycin biosynthesis protein PCZA361.9 TR:O52797 (EMBL:AJ223998) (267 aa) fasta scores: E(): 1.8e-08, 27.2% id in 235 aa. | 0.416 |
fabV | YPO1459 | YPO4104 | YPO1459 | Conserved hypothetical protein; Involved in the final reduction of the elongation cycle of fatty acid synthesis (FAS II). Catalyzes the reduction of a carbon- carbon double bond in an enoyl moiety that is covalently linked to an acyl carrier protein (ACP). | Putative enoyl-CoA hydratase; Similar to an internal region of Rattus norvegicus mitochondrial enoyl-CoA hydratase ECHS1 SW:ECHM_RAT (P14604) (290 aa) fasta scores: E(): 1.5e-13, 25.2% id in 238 aa, and to Bacillus subtilis putative polyketide biosynthesis enoyl-CoA hydratase homolog PksI SW:PKSI_BACSU (P40802) (249 aa) fasta scores: E(): 7.3e-24, 33.5% id in 248 aa. | 0.413 |