STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
cysNSulfate adenylyltransferase subunit 1; May be the GTPase, regulating ATP sulfurylase activity. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily. (478 aa)    
Predicted Functional Partners:
cysC
Adenylylsulfate kinase; Catalyzes the synthesis of activated sulfate.
 
 0.999
cysD
Similar to Escherichia coli sulfate adenylyltransferase subunit 2 CysD SW:CYSD_ECOLI (P21156) (302 aa) fasta scores: E(): 0, 89.7% id in 302 aa, and to Vibrio cholerae sulfate adenylate transferase subunit 2 Vc2560 TR:Q9KP19 (EMBL:AE004324) (315 aa) fasta scores: E(): 0, 81.1% id in 302 aa.
 0.999
cysA
Sulfate transport ATP-binding protein; Part of the ABC transporter complex CysAWTP involved in sulfate/thiosulfate import. Responsible for energy coupling to the transport system.
 
 
 0.994
cysW
Similar to Escherichia coli sulfate transport system permease protein CysW SW:CYSW_ECOLI (P16702) (291 aa) fasta scores: E(): 0, 78.0% id in 291 aa, and to Vibrio cholerae sulfate ABC transporter, permease protein Vc0540 TR:Q9KUI1 (EMBL:AE004140) (287 aa) fasta scores: E(): 0, 60.9% id in 271 aa.
  
 
 0.994
cysP
Similar to Escherichia coli thiosulfate-binding protein precursor CysP SW:CYSP_ECOLI (P16700) (338 aa) fasta scores: E(): 0, 74.1% id in 343 aa, and to Salmonella typhimurium thiosulfate-binding protein precursor CysP SW:CYSP_SALTY (P41031) (338 aa) fasta scores: E(): 0, 74.5% id in 329 aa. Similar to YPO0079 (47.7% identity in 321 aa overlap).
  
 
 0.994
sbp1
Similar to Escherichia coli sulfate-binding protein precursor Sbp involved in sulphate transport: SW:SUBI_ECOLI (P06997) (329 aa) fasta scores: E(): 0, 83.3% id in 329 aa.
  
 
 0.993
cysT
Sulfate transport system permease protein CysT; Part of the ABC transporter complex (TC 3.A.1.6.1) involved in sulfate/thiosulfate import; Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
  
 
 0.992
amtA
Inositol monophosphatase family protein; Converts adenosine-3',5'-bisphosphate (PAP) to AMP. Belongs to the inositol monophosphatase superfamily. CysQ family.
 
 
 0.963
cysJ
Sulfite reductase [NADPH] flavoprotein alpha-component; Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L-cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH -> FAD -> FMN to the hemoprotein component; Belongs to the NADPH-dependent sulphite reductase flavoprotein subunit CysJ family. In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.
  
  
 0.947
cysI
Phosphoadenosine phosphosulfate reductase (pseudogene); Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L-cysteine from sulfate. Belongs to the nitrite and sulfite reductase 4Fe-4S domain family.
  
  
 0.943
Your Current Organism:
Yersinia pestis
NCBI taxonomy Id: 214092
Other names: Y. pestis CO92, Yersinia pestis CO92, Yersinia pestis str. CO92, Yersinia pestis strain CO92
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