rplM protein (Yersinia pestis CO92) - STRING interaction network
"rplM" - 50S ribosomal protein L13 in Yersinia pestis CO92
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
protein homology
Your Input:
Gene Fusion
rplM50S ribosomal protein L13; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (142 aa)    
Predicted Functional Partners:
Similar to Escherichia coli 30S ribosomal protein S9 RpsI SW-RS9_ECOLI (P02363) (129 aa) fasta scores- E()- 0,92.2% id in 129 aa, and to Vibrio cholerae ribosomal protein S9 Vc0571 TR-Q9KUF0 (EMBL-AE004142) (130 aa) fasta scores- E()- 0, 86.9% id in 130 aa; Belongs to the universal ribosomal protein uS9 family (130 aa)
50S ribosomal protein L11; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors (142 aa)
50S ribosomal protein L2; One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome (274 aa)
50S ribosomal protein L16; Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (136 aa)
50S ribosomal protein L19; This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (115 aa)
50S ribosomal protein L5; This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs (179 aa)
Similar to Escherichia coli 50S ribosomal protein L27 RpmA SW-RL27_ECOLI (P02427) (84 aa) fasta scores- E()- 5e-31, 94.0% id in 84 aa, and to Vibrio cholerae ribosomal protein L27 Vc0436 TR-Q9KUS9 (EMBL-AE004131) (86 aa) fasta scores- E()- 1.2e-29, 91.6% id in 83 aa; Belongs to the bacterial ribosomal protein bL27 family (85 aa)
50S ribosomal protein L3; One of the primary rRNA binding proteins, it binds directly near the 3’-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (209 aa)
50S ribosomal protein L22; This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity) (110 aa)
50S ribosomal protein L6; This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center (177 aa)
Your Current Organism:
Yersinia pestis CO92
NCBI taxonomy Id: 214092
Other names: Y. pestis CO92, Yersinia pestis CO92, Yersinia pestis str. CO92, Yersinia pestis strain CO92
Server load: low (11%) [HD]