node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
YPO1610 | aroA | YPO1610 | YPO1390 | Similar to Neisseria meningitidis shikimate dehydrogenase AroE TR:P95381 (EMBL:U82834) (269 aa) fasta scores: E(): 1.3e-08, 26.4% id in 239 aa, and to Deinococcus radiodurans shikimate 5-dehydrogenase, putative Dr0077 TR:Q9RY73 (EMBL:AE001871) (273 aa) fasta scores: E(): 0, 57.7% id in 267 aa. | 3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. | 0.866 |
YPO1610 | aroB | YPO1610 | YPO0152 | Similar to Neisseria meningitidis shikimate dehydrogenase AroE TR:P95381 (EMBL:U82834) (269 aa) fasta scores: E(): 1.3e-08, 26.4% id in 239 aa, and to Deinococcus radiodurans shikimate 5-dehydrogenase, putative Dr0077 TR:Q9RY73 (EMBL:AE001871) (273 aa) fasta scores: E(): 0, 57.7% id in 267 aa. | 3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ); Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family. | 0.702 |
YPO1610 | aroE | YPO1610 | YPO0246 | Similar to Neisseria meningitidis shikimate dehydrogenase AroE TR:P95381 (EMBL:U82834) (269 aa) fasta scores: E(): 1.3e-08, 26.4% id in 239 aa, and to Deinococcus radiodurans shikimate 5-dehydrogenase, putative Dr0077 TR:Q9RY73 (EMBL:AE001871) (273 aa) fasta scores: E(): 0, 57.7% id in 267 aa. | Shikimate 5-dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). | 0.934 |
YPO1610 | aroK | YPO1610 | YPO0151 | Similar to Neisseria meningitidis shikimate dehydrogenase AroE TR:P95381 (EMBL:U82834) (269 aa) fasta scores: E(): 1.3e-08, 26.4% id in 239 aa, and to Deinococcus radiodurans shikimate 5-dehydrogenase, putative Dr0077 TR:Q9RY73 (EMBL:AE001871) (273 aa) fasta scores: E(): 0, 57.7% id in 267 aa. | Shikimate kinase I; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family. | 0.982 |
YPO1610 | aroQ | YPO1610 | YPO3660 | Similar to Neisseria meningitidis shikimate dehydrogenase AroE TR:P95381 (EMBL:U82834) (269 aa) fasta scores: E(): 1.3e-08, 26.4% id in 239 aa, and to Deinococcus radiodurans shikimate 5-dehydrogenase, putative Dr0077 TR:Q9RY73 (EMBL:AE001871) (273 aa) fasta scores: E(): 0, 57.7% id in 267 aa. | Putative class II dehydroquinase; Catalyzes a trans-dehydration via an enolate intermediate. Belongs to the type-II 3-dehydroquinase family. | 0.970 |
YPO1610 | menF | YPO1610 | YPO2528 | Similar to Neisseria meningitidis shikimate dehydrogenase AroE TR:P95381 (EMBL:U82834) (269 aa) fasta scores: E(): 1.3e-08, 26.4% id in 239 aa, and to Deinococcus radiodurans shikimate 5-dehydrogenase, putative Dr0077 TR:Q9RY73 (EMBL:AE001871) (273 aa) fasta scores: E(): 0, 57.7% id in 267 aa. | Menaquinone-specific isochorismate synthase; Catalyzes the conversion of chorismate to isochorismate. | 0.841 |
accB | aroQ | YPO3659 | YPO3660 | Biotin carboxyl carrier protein of acetyl-CoA carboxylase; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. | Putative class II dehydroquinase; Catalyzes a trans-dehydration via an enolate intermediate. Belongs to the type-II 3-dehydroquinase family. | 0.784 |
accB | rplM | YPO3659 | YPO3563 | Biotin carboxyl carrier protein of acetyl-CoA carboxylase; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. | 50S ribosomal protein L13; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly. | 0.828 |
accB | tig | YPO3659 | YPO3158 | Biotin carboxyl carrier protein of acetyl-CoA carboxylase; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. | Trigger factor; Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase; Belongs to the FKBP-type PPIase family. Tig subfamily. | 0.504 |
aroA | YPO1610 | YPO1390 | YPO1610 | 3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. | Similar to Neisseria meningitidis shikimate dehydrogenase AroE TR:P95381 (EMBL:U82834) (269 aa) fasta scores: E(): 1.3e-08, 26.4% id in 239 aa, and to Deinococcus radiodurans shikimate 5-dehydrogenase, putative Dr0077 TR:Q9RY73 (EMBL:AE001871) (273 aa) fasta scores: E(): 0, 57.7% id in 267 aa. | 0.866 |
aroA | aroB | YPO1390 | YPO0152 | 3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. | 3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ); Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family. | 0.994 |
aroA | aroE | YPO1390 | YPO0246 | 3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. | Shikimate 5-dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). | 0.991 |
aroA | aroK | YPO1390 | YPO0151 | 3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. | Shikimate kinase I; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family. | 0.994 |
aroA | aroQ | YPO1390 | YPO3660 | 3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. | Putative class II dehydroquinase; Catalyzes a trans-dehydration via an enolate intermediate. Belongs to the type-II 3-dehydroquinase family. | 0.627 |
aroA | menF | YPO1390 | YPO2528 | 3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. | Menaquinone-specific isochorismate synthase; Catalyzes the conversion of chorismate to isochorismate. | 0.575 |
aroB | YPO1610 | YPO0152 | YPO1610 | 3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ); Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family. | Similar to Neisseria meningitidis shikimate dehydrogenase AroE TR:P95381 (EMBL:U82834) (269 aa) fasta scores: E(): 1.3e-08, 26.4% id in 239 aa, and to Deinococcus radiodurans shikimate 5-dehydrogenase, putative Dr0077 TR:Q9RY73 (EMBL:AE001871) (273 aa) fasta scores: E(): 0, 57.7% id in 267 aa. | 0.702 |
aroB | aroA | YPO0152 | YPO1390 | 3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ); Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family. | 3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. | 0.994 |
aroB | aroE | YPO0152 | YPO0246 | 3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ); Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family. | Shikimate 5-dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). | 0.983 |
aroB | aroK | YPO0152 | YPO0151 | 3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ); Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family. | Shikimate kinase I; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family. | 0.999 |
aroB | aroQ | YPO0152 | YPO3660 | 3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ); Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family. | Putative class II dehydroquinase; Catalyzes a trans-dehydration via an enolate intermediate. Belongs to the type-II 3-dehydroquinase family. | 0.994 |