STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
aarFUbiquinone biosynthesis protein; Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis. (543 aa)    
Predicted Functional Partners:
ubiE
Ubiquinone/menaquinone biosynthesis methyltransferase; Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3- methyl-6-methoxy-1,4-benzoquinol (DMQH2).
 
  
 0.858
YPO3780
Similar to Escherichia coli hypothetical protein YigP SW:YIGP_ECOLI (P27852) (201 aa) fasta scores: E(): 0,56.9% id in 197 aa, and to Salmonella typhimurium LT2 YigP protein TR:Q9L6M5 (EMBL:AF233324) (201 aa) fasta scores: E(): 0, 56.9% id in 197 aa.
  
  
 0.850
pufX
3-demethylubiquinone-9 3-methyltransferase; O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway; Belongs to the methyltransferase superfamily. UbiG/COQ3 family.
  
 
 0.732
visC
Putative monooxygenase; Similar to Escherichia coli hypothetical VisC protein (which is required for the biosynthesis of ubiquinone) SW:VISC_ECOLI (P25535) (400 aa) fasta scores: E(): 0, 71.4% id in 402 aa, and to Escherichia coli 2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase UbiF SW:UBIF_ECOLI (P75728) (391 aa) fasta scores: E(): 0,38.2% id in 395 aa.
  
 
 0.713
b4040
4-hydroxybenzoate octaprenyltransferase; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate.
  
 
 0.651
mtta2
Sec-independent protein translocase protein TatB; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation.
  
  
 0.637
smtA
Putative methyltransferase; Catalyzes the methylation of 5-carboxymethoxyuridine (cmo5U) to form 5-methoxycarbonylmethoxyuridine (mcmo5U) at position 34 in tRNAs; Belongs to the class I-like SAM-binding methyltransferase superfamily. CmoM family.
  
 
 0.635
YPO1102
Similar to Escherichia coli hypothetical protein YfjG SW:YFJG_ECOLI (P52121) (158 aa) fasta scores: E(): 0,79.3% id in 145 aa, and to Vibrio cholerae hypothetical protein VC0849 SW:Y849_VIBCH (P52122) (144 aa) fasta scores: E(): 0, 69.0% id in 142 aa.
  
 
 
 0.634
ubiF
Similar to Escherichia coli 2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase UbiF SW:UBIF_ECOLI (P75728) (391 aa) fasta scores: E(): 0,63.8% id in 390 aa, and to Vibrio cholerae VisC-related protein VC0963 TR:Q9KTD9 (EMBL:AE004178) (397 aa) fasta scores: E(): 0, 56.9% id in 390 aa.
  
 
 0.633
mttB
Sec-independent protein translocase protein TatC; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides.
  
  
 0.627
Your Current Organism:
Yersinia pestis
NCBI taxonomy Id: 214092
Other names: Y. pestis CO92, Yersinia pestis CO92, Yersinia pestis str. CO92, Yersinia pestis strain CO92
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.