STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
argHSimilar to Escherichia coli argininosuccinate lyase ArgH SW:ARLY_ECOLI (P11447) (457 aa) fasta scores: E(): 0,89.0% id in 456 aa, and to Vibrio cholerae argininosuccinate lyase VC2641 TR:Q9KNT9 (EMBL:AE004330) (458 aa) fasta scores: E(): 0, 74.3% id in 456 aa. (457 aa)    
Predicted Functional Partners:
argG
Similar to Escherichia coli argininosuccinate synthase ArgG SW:ASSY_ECOLI (P22767) (446 aa) fasta scores: E(): 0, 90.5% id in 440 aa, and to Neisseria meningitidis argininosuccinate synthase ArgG or Nma0303 TR:Q9JWM1 (EMBL:AL162752) (447 aa) fasta scores: E(): 0, 80.7% id in 440 aa; Belongs to the argininosuccinate synthase family. Type 2 subfamily.
 
 
 0.998
argB
Acetylglutamate kinase; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate.
 
 
 0.984
argA
Similar to Escherichia coli amino-acid acetyltransferase ArgA SW:ARGA_ECOLI (P08205) (443 aa) fasta scores: E(): 0, 87.3% id in 441 aa, and to Vibrio cholerae N-acetylglutamate synthase VC2316 TR:Q9KPQ0 (EMBL:AE004301) (456 aa) fasta scores: E(): 0, 65.8% id in 445 aa; Belongs to the acetyltransferase family. ArgA subfamily.
 
 
 0.971
argC
N-acetyl-gamma-glutamyl-phosphate reductase; Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde. Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
 
  
 0.963
fumA
Fumarate hydratase, class I; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family.
  
 
 0.960
purB
Similar to Escherichia coli adenylosuccinate lyase PurB SW:PUR8_ECOLI (P25739) (456 aa) fasta scores: E(): 0,88.6% id in 456 aa, and to Vibrio cholerae adenylosuccinate lyase Vc1126 TR:Q9KSY0 (EMBL:AE004193) (456 aa) fasta scores: E(): 0, 78.5% id in 456 aa.
    
 0.951
mdh
Malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate.
   
 0.951
gltA
Citrate synthase GltA; Similar to Escherichia coli citrate synthase GltA SW:CISY_ECOLI (P00891) (427 aa) fasta scores: E(): 0, 86.7% id in 427 aa, and to Vibrio cholerae citrate synthase VC2092 TR:Q9KQA8 (EMBL:AE004283) (431 aa) fasta scores: E(): 0, 78.0% id in 422 aa.
  
 
 0.948
argM
Succinylornithine aminotransferase; Catalyzes the transamination of N(2)-succinylornithine and alpha-ketoglutarate into N(2)-succinylglutamate semialdehyde and glutamate. Can also act as an acetylornithine aminotransferase. Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. AstC subfamily.
 
  
 0.947
fumC
Fumarate hydratase, class II; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
   
 
0.946
Your Current Organism:
Yersinia pestis
NCBI taxonomy Id: 214092
Other names: Y. pestis CO92, Yersinia pestis CO92, Yersinia pestis str. CO92, Yersinia pestis strain CO92
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